Results 1 to 10 of about 122,058 (148)

Molecular mechanisms of thiazide-like diuretics-mediated inhibition of the human Na-Cl cotransporter [PDF]

open access: yesNature Communications
Thiazide-type and thiazide-like diuretics are structurally distinct first-line antihypertensive drugs that target the sodium-chloride cotransporter (NCC) in the kidney.
Chien-Ling Lee   +2 more
doaj   +2 more sources

Association between changes in loop diuretic dose and outcomes in acute heart failure

open access: yesESC Heart Failure, 2023
Aims Little is known about the association between the starting of or dose changes in loop diuretics during acute heart failure (AHF) hospitalization and post‐discharge outcomes. We investigated the clinical impact of starting loop diuretics and changing
Yuta Seko   +27 more
doaj   +1 more source

Tactics of antihypertensive therapy during COVID-19 pandemic

open access: yesТерапевтический архив, 2021
Results of foreign and Russian studies indicate a higher mortality rate of patients with concomitant cardiovascular diseases (CVD) due to the new coronavirus infection COVID-19.
Valery I. Podzolkov   +4 more
doaj   +1 more source

All diuretics used in the treatment of hypertension are not the same

open access: yesTürk Kardiyoloji Derneği Arşivi, 2017
Summary– Diuretics have been used for years to treat hypertension as both a monotherapy and in combination. Hydrochlorothiazide, indapamide, and chlorthalidone have frequently been considered in the same category as thiazide diuretics, but there is no ...
Serkan Asil, Enver Atalar
doaj   +1 more source

Diuretics and Hypokalemia [PDF]

open access: yesActa Medica Iranica, 1970
We have studied hypokalemic action of different diuretics in a cooperative study on 28 patients and our results are as follows: I. 28 patients (18 male and 10 female) were the subject of our present study. 2. E. C. G.
Ali A. Handjani   +2 more
doaj   +2 more sources

Diuretics in primary hypertension – Reloaded

open access: yesIndian Heart Journal, 2016
Diuretics have long been cherished as drugs of choice for uncomplicated primary hypertension. Robust mortality and morbidity data is available for diuretics to back this strategy.
Sundeep Mishra
doaj   +1 more source

Impact of Albumin Binding Function on Pharmacokinetics and Pharmacodynamics of Furosemide

open access: yesMedicina, 2022
Background and Objectives: Albumin binding of the loop diuretic furosemide forms the basis for its transport to the kidney and subsequent tubular secretion, which is a prerequisite for its therapeutic effects.
Gerd Klinkmann   +6 more
doaj   +1 more source

Long-term amlodipine-based combination therapy attenuates seasonal variation of blood pressure in hypertensive patients

open access: yesClinical and Experimental Hypertension, 2021
Objectives: This study was to investigate whether long-term amlodipine-based combination therapy attenuates seasonal variation of office blood pressure (BP) in hypertensive patients.
Hua-song Xia   +4 more
doaj   +1 more source

The incidence and risk factors analysis of acute kidney injury in hospitalized patients received diuretics: A single-center retrospective study

open access: yesFrontiers in Pharmacology, 2022
Diuretics have been one of the well-known nephrotoxic drugs which can lead to acute kidney injury (AKI). However, there are few real-world studies on the incidence of AKI in hospitalized patients received diuretics.
Ruiqiu Zhang   +8 more
doaj   +1 more source

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