Results 51 to 60 of about 132,183 (303)

HFrEF pharmacological treatment: diuretics

, 2018
Diuretics are an important part of the therapy for heart failure with reduced ejection fraction (HFrEF). These agents lead to amelioration of clinical symptoms and improvement in haemodynamics. There is little evidence, however, to support an association
Mariell Jessup, Rhondalyn Forde-McLean
core   +1 more source

Longitudinal Echocardiographic Surveillance of Aortic Dilation in a Phenotype‐Enriched Turner Syndrome Cohort

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Turner syndrome (TS) is associated with thoracic aortopathy and increased risk for aortic dissection, yet the natural history of aortic dilation is not well understood. We performed a retrospective longitudinal study of individuals with TS who participated in the TS Society of the United States Healthy Heart Project between 2003 and 2023 ...
Dylan Doerner, Matthew R. Johnson, Sara Mansoorshahi, Rakesh Kathiresan, Katelyn Abel, Jonathan G. You, Emilio Quezada, Siddharth K. Prakash   +7 more
wiley   +1 more source

Lower Extremity Injuries and Revision Surgery Rates are Increased in Patients With Anorexia Nervosa and Bulimia Nervosa Compared With Controls

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To compare lower extremity soft tissue injury and revision surgery rates for patients with anorexia nervosa (AN) and bulimia nervosa (BN) compared with matched controls. Methods This retrospective cohort study used a deidentified claims database.
Jackson G. Woodrow, David G. Deckey, Eugenia Lin, Jack M. Haglin, Joshua S. Bingham, Karan A. Patel, Callie M. Davies, Steven K. Poon   +7 more
wiley   +1 more source

Diuretics

, 2018
Despite being among the most ancient medications in a historic perspective, diuretics also hold the merit of representing an evergreen challenge for research and related drugs development.
Ferri C., Del Pinto R.
core   +1 more source

Trends in 25 years of antihypertensive agent utilization in Croatia – an alert for scientific community and healthcare providers

British Journal of Clinical Pharmacology, EarlyView.
Aims Hypertension is a leading modifiable risk factor for cardiovascular mortality worldwide. This study aimed to evaluate 25‐year trends in antihypertensive agent (AHA) utilization in Croatia between 2000 and 2024. Methods We conducted a national, population‐based analysis using IMS and IQVIA pharmaceutical databases.
Andrej Belančić, Marta Kučan Štiglić, Ana Jelaković, Bojan Jelaković, Dinko Vitezić   +4 more
wiley   +1 more source

Establishment of diuretic activity indicators for (3-thio-4-R-4-H-1,2,4-triazole-5-yl)(phenyl)methanols and their derivatives

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2018
Diuretic drugs are drugs that, by blocking the transport systems of the renal tubules, promote the removal of excess electrolytes and water from the body, normalization of the internal environment.
A. M. Rud, A. G. Kaplaushenko, Ye. S. Pruglo, Yu. S. Frolova   +3 more
doaj   +1 more source

Blood pressure effects of SGLT2 inhibitors and GLP‐1 receptor agonists: Mechanisms, trial evidence and Real‐world data

British Journal of Clinical Pharmacology, EarlyView.
SGLT2 inhibitors and GLP‐1 receptor agonists modestly lower blood pressure across diverse patient populations, including those without diabetes. These effects appear largely independent of glycaemic control and offer additive value in high‐risk patients with overlapping comorbidities.
Andrej Belančić, Yusuf Ziya Sener, Marijana Vučković, Joseph Edgar Blais, Almir Fajkić, Emina Sher, Mislav Radić, Josipa Radić   +7 more
wiley   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Mediterranean Basin Erica Species: Traditional Uses, Phytochemistry and Pharmacological Properties

Molecules
Erica species native to the Mediterranean basin are the principal Ericas that have found use in traditional medicine. Examples include treatments for urinary tract disorders, inflammatory conditions, gastrointestinal ailments and weight loss. This review
Khadijah A. Jabal, Maria Pigott, Helen Sheridan, John J. Walsh   +3 more
doaj   +1 more source

Diuretics

Journal of Cardiovascular Pharmacology and Therapeutics, 2013
Diuretics have been recommended as first-line treatment of hypertension and are also valuable in the management of hypervolemia and electrolyte disorders. This review summarizes the key features of the most commonly used diuretics. We then provide an update of clinical trials for diuretics during the past 5 years.
George C, Roush, Ramdeep, Kaur, Michael E, Ernst   +2 more
openaire   +2 more sources