Background Lung adenocarcinoma (LUAD) is a prevalent malignancy with poor survival outcomes, underscoring the need for better biomarkers and therapeutic targets. Dickkopf-1 (DKK1), a secreted Wnt pathway inhibitor, is dysregulated in many cancers and can
Yanhong Wang +7 more
doaj +1 more source
Определение полиморфизмов гена dkk1 у больных с диагнозом остеоартрит
Остеоартрит (OA) характеризуется прогрессивным разрушением суставного хряща при совместном сужении межхрящевого пространства. Исследования патогенеза OA показали, что Wnt-b-катениновый сигнал может играть важную роль в развитии OA.
Габдулина, Г.Х. +2 more
core +1 more source
Epigenetic Activation of the KDM6B-DKK1 Axis Promotes Colorectal Cancer Peritoneal Metastasis Through Wnt/β-Catenin-Associated EMT. [PDF]
Zhai Z, Chen J, Yang Y, Li M.
europepmc +1 more source
Secreted frizzled-related protein 3 is associated with metabolic disturbances in gestational diabetes. [PDF]
Ueland T +8 more
europepmc +1 more source
Unraveling the roles of DKK1 and S100P in pancreatic ductal adenocarcinoma: Insights from machine learning, single-cell/spatial transcriptomics, and functional validation. [PDF]
Mao Y +8 more
europepmc +1 more source
Single-cell transcriptomic analysis reveals fatty acid metabolic heterogeneity and identifies DKK1 as a candidate prognostic factor in osteosarcoma. [PDF]
Wang L, Gao M, Liang Z.
europepmc +1 more source
Myeloid cell reprogramming combined with zoledronic acid effectively suppresses bone metastasis. [PDF]
Luo Y +8 more
europepmc +1 more source

