Results 91 to 100 of about 27,737 (256)

Cesni‐cel (ARI0002h) in ultra‐high‐risk multiple myeloma with plasma cell leukaemia or central nervous system involvement

British Journal of Haematology, EarlyView.
ARI0002h induced response in 15/17 patients with plasma cell leukaemia (PCL)/central nervous system (CNS)‐multiple myeloma (MM) (87% achieved ≥ very good partial response [VGPR]) with a median progression‐free survival (PFS)/overall survival (OS) of 10.5 and 15.9 months respectively.
Carlos Jimenez‐Mira, Natalia Tovar, Núria Martínez‐Cibrián, Verónica González‐Calle, Nil Albiol, Nieves López‐Muñoz, Aina Oliver‐Caldés, Azucena González, José Miguel Mateos, Marta Español‐Rego, Laura Rosiñol, Manel Juan, Paola Charry, José María Sanchez‐Pina, Sergio Navarro, Daniel Munárriz, Lucía López‐Corral, Valentín Ortiz‐Maldonado, Sara Varea, Eulalia Olesti, Julio Delgado, Álvaro Urbano‐Ispizua, Joaquín Martínez‐López, María Victoria Mateos, Luis Gerardo Rodríguez‐Lobato, Carlos Fernández de Larrea   +25 more
wiley   +1 more source

Toughness characterization of DLC and Ti doped DLC [PDF]

, 2010
As DLC and DLC based ceramic thin films are increasingly finding their way in engineering applications, thin film toughness assessment becomes important. However, it has not been thoroughly explored.
Tey, Xiang Wei.
core  

Scaffold‐free three‐dimensional culture of chronic lymphocytic leukaemia preserves B–T‐cell cross‐talk and enables drug response profiling

British Journal of Haematology, EarlyView.
Summary Chronic lymphocytic leukaemia (CLL) presents a complex biological and clinical landscape, strongly influenced by the tumour microenvironment (TME). To better capture this heterogeneity, we have developed patient‐derived lymphoma spheroids from CLL samples (CLL‐PDLS), which recapitulate the cross‐talk between malignant cells and the autologous ...
Heribert Playa‐Albinyana, Ariadna Giró, Juan A. Piñeyroa, Ferran Araujo‐Ayala, Cèlia Dobaño‐López, Sara Otín‐Sánchez, Elías Campo, Christine Bezombes, Patricia Pérez‐Galán, Dolors Colomer   +9 more
wiley   +1 more source

Inhibition of kynurenine 3‐monooxygenase (KMO) reduces fentanyl and sucrose intake and relapse‐like behaviour in rats

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Opioid use disorder, particularly involving fentanyl, poses major challenges due to high relapse rates and limited effectiveness of pharmacotherapies. The kynurenine pathway has emerged as a target for addiction treatment through its modulation of glutamatergic and dopaminergic neurotransmission.
Carlos Núñez‐de la Calle, Lluna Careaga, Stefanie Malan‐Müller, Álvaro del Río‐García, Yaiza Trueba, Leticia Gil de Biedma‐Elduayen, Nuria Morales‐Puerto, Rebeca Vidal, Åsa Wiman, Sophie Erhardt, María Dolores Gutiérrez‐López, Esther O'Shea, María Isabel Colado   +12 more
wiley   +1 more source

A DLC FILM FABRICATION METHOD [PDF]

, 2016
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core  

Fluorinated DLC for tribological applications [PDF]

, 2009
Diamond-like carbon (DLC) can be lubricious with a frictional coefficient comparable to Teflon (e.g. 0.1). Hydrogen terminated DLC may be more lubricious than pure carbon DLC, but fluorinated DLC can be super lubricious with frictional coefficient less ...
Kan, Ming Chi, Sung, James C., Sung, Michael   +2 more
core   +1 more source

Os títulos de contos que crianças (re)contam: uma “poética” da brevidade sem a angústia da influência

Forma Breve, 2019
Se ninguém nega a importância da literatura na escola, já o modo como se ensina a conhecer a língua dos textos literários e, sobretudo, o papel que a escrita pode ter neste processo é polémico e discutível (Tauveron, 2005; Pereira, 2008; 2014).
Luísa Álvares Pereira, Rosa Lídia Coimbra, Eduardo Calil   +2 more
doaj   +1 more source

A Zeolitic Pyrimidine Framework (ZPF) Nanoplatform Co‐Delivers a DNAzyme and a Protein Prodrug for Cascade‐Activated Tumour Therapy

Cell Proliferation, EarlyView.
A zeolitic framework co‐delivers a DNAzyme and a protein prodrug to tumour cells and executes a self‐amplifying therapeutic cascade: the DNAzyme elevates tumour oxidative stress to activate a caged RNase A prodrug. This spatiotemporally controlled synergy converts a genetic input into potent enzymatic cytotoxicity, suppressing tumour growth.
Yan Huang, Xingjie Hu, Jinli Sun, Min Yin, Nan Chen   +4 more
wiley   +1 more source

Laser micromachining of sputtered DLC films [PDF]

, 2006
DLC films with different thicknesses (from 100 nm to 1.9 μm) were deposited using sputtering of graphite target in pure argon atmosphere without substrate heating. Film microstructures (sp2/sp3 ratio) and mechanical properties (modulus, hardness, stress)
Zhang, Sam, Fu, YQ, Zhang, S, Milne, WI, Luo, J. K., Flewitt, AJ, Luo, JK, ,, Ong, SE, Ong, Soon-Eng, Milne, William, Fu, Yong Qing, Flewitt, Andrew   +12 more
core   +1 more source

Publicações recebidas

Ágora, 2020
João Manuel Nunes Torrão
doaj   +1 more source