Results 231 to 240 of about 107,340 (312)

A Radioresistant‐Tumor‐Targeted Nanoparticle for X‐Ray‐Controlled Nitric Oxide Release to Potentiate Radiotherapy

Advanced Science, EarlyView.
The PBTN targets GRP78 and, upon X‐ray irradiation, generates ONOO− to induce immunogenic cell death, thereby activating CD8+ T cells and establishing a systemic antitumor immune response. ABSTRACT Nitric oxide (NO) treated radioresistant tumors by relieving hypoxia and blocking DNA repair, but its nonselective toxicity has precluded therapeutic use ...
Wanze Zhang, Xiaoyan Yin, Ting Wang, Hongfu Zhao, Zhipeng Zhao, Jinbao Wang, Cheng Tao, Xuanchu Ge, Yanze Li, Linlin Liu, Fuxin Xue   +10 more
wiley   +1 more source

Automated deep learning segmentation and planning for left-sided breast radiotherapy with minimised adaptations based on dose, TCP and NTCP criteria. [PDF]

Phys Imaging Radiat Oncol
van Acht N, Ciobotaru A, van der Sangen M, Theuws J, Bluemink J, Hurkmans C.   +5 more
europepmc   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

Advanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang, Ya‐Ning Wang, Da Lin, Jia‐Yang Xu, Feng‐Yuan Qi, Hui‐Ling Cui, Hui‐Jie Lu, Min Qiao, Edward Topp, Dong Zhu, Matthias C. Rillig, Yong‐Guan Zhu   +11 more
wiley   +1 more source

A dorsal hippocampus-prodynorphinergic dorsolateral septum-to-lateral hypothalamus circuit mediates contextual gating of feeding. [PDF]

Neuron
Goode TD, Bernstein MX, Totty MS, Alipio JB, Vicidomini C, Pathak D, Besnard A, Chizari D, Sachdev N, Kritzer MD, Chung A, Duan X, Macosko E, Hicks SC, Zweifel LS, Sahay A.   +15 more
europepmc   +1 more source

Microscale Mapping of Fiber Strain and Damage in Composite Wrinkled Laminates Using Computed Tomography Assisted Wide‐Angle X‐Ray Scattering

Advanced Science, EarlyView.
This study combines full‐field tomography with diffraction mapping to quantify radial (ε002$\varepsilon _{002}$) and axial (ε100$\varepsilon _{100}$) lattice strain in wrinkled carbon‐fiber specimens for the first time. Radial microstrain gradients (−14.5 µεMPa$\varepsilon \mathrm{MPa}$−1) are found to signal damage‐prone zones ahead of failure, which ...
Hoang Minh Luong, James Trevarthen, Igor Dolbnya, Wadwan Singhapong, Nicholas Pilato, Richard Butler, Jiraphant Srisuriyachot, Alexander J. G. Lunt   +7 more
wiley   +1 more source

Digital Leadership Scale for Clinical Nurses: Development and Validation of an Instrument. [PDF]

JMIR Nurs
Lee JH, Jung SY.
europepmc   +1 more source

13 IBOGA ALKALOIDSの合成研究 : dl-Ibogamine,dl-Epiibogamine dl-Ibogaine,dl-Epiibogaine,dl-Tabernanthine,dl-Epitabernanthineの全合成

Symposium on the Chemistry of Natural Products, symposium papers, 1969
Ban, Y., Ikezaki, M., Wakamatsu, T., Oishi, T.   +3 more
openaire   +1 more source

Dual‐Responsive Dynamic Covalent Bond‐Based Assembly of Lipid‐Nanozyme Systems via Multi‐Target Synergy and Efficient Target Enrichment for Ischemic Stroke Therapy

Advanced Science, EarlyView.
This system adopts a biomimetic phospholipid structure, covalently binding iNOS inhibitors, neuroprotective agent PCA and vitamin E derivatives through pH/ROS dual‐responsive bonds, and assembles them with Prussian blue nanozyme to form PBB@AHA. It can efficiently penetrate the blood‐brain barrier and simultaneously release multiple active components ...
Mengcheng Guo, Qingran Guan, Guanyu Qiao, Lixue Zhang, Man Liu, Zhen Li, Qingbiao Yang, Meili Shen, Linlin Liu, Yapeng Li   +9 more
wiley   +1 more source

Correction to: Rethinking the system of post-exposure prophylaxis against rabies in veterinary practice

Discover Applied Sciences
Krishna Prasad Acharya, Sarita Phuyal, Jiyeon Oh, Dong Keon Yon, Francesco Branda   +4 more
doaj   +1 more source

Motor-to-Limbic Design of Direct Synaptic Communication between Dopamine Neurons in the Midbrain. [PDF]

J Neurosci
Hammer-Bahador N, Tian G, Fischer B, Stojanovic S, Beier K, Roeper J.   +5 more
europepmc   +1 more source