Results 51 to 60 of about 75,518 (220)

Transductive Multi-View Zero-Shot Learning [PDF]

, 2015
(c) 2012. The copyright of this document resides with its authors.
Fu, Y, Gong, S, Hospedales, TM, Xiang, T
core   +4 more sources

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Endogenous “Time Bomb” – Mislocalized Phospholipase A2 as a Critical Mediator of Ultra‐Rapid Mortality in Sepsis and Acute Lung Injury

Advanced Science, EarlyView.
Phospholipase A2 (PLA2), a dormant enzyme, becomes lethal when activated—collapsing lungs in minutes. Our dual therapy (DOPS + varespladib) boosts survival from 0% to >90% in sepsis/ALI. A breakthrough for acute lung injury treatment. ABSTRACT This study reveals that phospholipase A2 (PLA2), normally stable and nontoxic, can be activated specifically ...
Jianyu Wang, Zhongxing Xu, Lin Wang, Xin Sui, Yuan Luo, Xiuli Zhao, Jun Yang, Yongan Wang   +7 more
wiley   +1 more source

Health related quality of life and comorbidity. A descriptive analysis comparing EQ-5D dimensions of patients in the German disease management program for type 2 diabetes and patients in routine care

BMC Health Services Research, 2011
Background The co-occurance of multiple medical conditions has a negative impact on health related quality of life (HRQoL) for patients with type 2 diabetes. These patients demand for intensified care programs.
Kunz Cornelia, Szecsenyi Joachim, Natanzon Iris, Urban Elisabeth, Miksch Antje, Ose Dominik, Freund Tobias   +6 more
doaj   +1 more source

Beyond Transconductance: Cell‐Polymer Coupling Determines Fidelity in Action Potential Recording via Electrolyte‐Gated Polymer Transistors

Advanced Science, EarlyView.
High electrical performance alone does not guarantee efficient bioelectronic signal transduction. Despite excellent mixed ionic‐electronic conduction, recordings from cardiomyocytes reveal that p(g2T‐TT)‐based OECTs predominantly transduce field potential FP‐like signals due to weak cell‐polymer coupling.
Giulia Zoe Zemignani, Elena Mancinelli, Gabriele Tullii, Aleksandr Khudiakov, Cristiano Bortolotti, Shubham Tanwar, Peter J. Schwartz, Luca Sala, Maria Rosa Antognazza, Mario Caironi, Adrica Kyndiah   +10 more
wiley   +1 more source

Cationic micelle-based siRNA delivery for efficient colon cancer gene therapy

Nanoscale Research Letters, 2019
Small interfering RNA (siRNA)-based gene therapy has provided an alternative strategy for cancer therapy. One of the key components within gene therapy process is the delivery system.
Yongping Lu, Lei Zhong, Zhongliang Jiang, Haixia Pan, Yuanfa Zhang, Guonian Zhu, Lan Bai, Rongsheng Tong, Jianyou Shi, Xingmei Duan   +9 more
doaj   +1 more source

Cosmic rays from AGN, the knee energy mass scale and dark matter particles [PDF]

, 2011
Following the possibility of a new mass scale at the 3 PeV knee energy of the cosmic ray energy spectrum, the author suggests that the mass for the dark matter particle should be 8.1 TeV, using GLMR supersymmetry theory .
Tomozawa, Yukio
core  

Alzheimer's Disease Risk Factor APOE4 Exerts Dimorphic Effects on Female Bone

Advanced Science, EarlyView.
In aging bone, osteocytes accumulate neurodegenerative risk factor Apolipoprotein E (APOE). A humanized version of the Alzheimer's disease risk allele APOE4 altered the mouse bone transcriptome and proteome, with effects in female bone surpassing the brain, including bone fragility due to suppressed osteocytic maintenance of bone quality, identifying ...
Charles A. Schurman, Gurcharan Kaur, Serra Kaya, Joanna Bons, Carlos Galicia Aguirre, Qi Liu, Christina D. King, Kenneth A. Wilson, Harrison L. Baker, Mikayla Hady, Nadja Maldonado Luna, Gregor Bieri, Saul A. Villeda, Lisa M. Ellerby, Birgit Schilling, Tamara Alliston   +15 more
wiley   +1 more source

DATUM in Action [PDF]

, 2012
This collaborative research data management planning project (hereafter the RDMP project) sought to help a collaborative group of researchers working on an EU FP7 staff exchange project (hereafter the EU project) to define and implement good research ...
Childs, Sue, McLeod, Julie
core  

In Situ Polymerized Composite Electrolytes for High‐Performance Solid‐State Lithium Batteries: A Review

Advanced Science, EarlyView.
This review systematically explores the recent advances in in situ polymerized composite polymer electrolytes (CPEs) for solid‐state lithium batteries. It covers the fundamentals of reaction mechanisms, monomer chemistry, and their impact on interfacial stability, ionic conductivity, and electrochemical performance.
Jialin Li, Yufen Yan, Xiaoju Wang, Yuhui Huang, Zhen Huang, Lingjie Zhang, Ningzhong Bao, Zijian Hong, Yongjun Wu, Dali Ji   +9 more
wiley   +1 more source