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Bacterial Infection Promotes DNA Hypermethylation

Journal of Dental Research, 2007
Maternal oral infection, caused by bacteria such as C. rectus or P. gingivalis, has been implicated as a potential source of placental and fetal infection and inflammatory challenge, which increases the relative risk for pre-term delivery and growth restriction.
Y A, Bobetsis   +8 more
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DNA transfer in bacterial conjugation

Journal of Molecular Biology, 1966
Chromosome transfer from Hfr to F − cells was analyzed by labeling the DNA of the Hfr cells with [ 3 H]thymine prior to mating, and/or by labeling any DNA made during mating. The F − cells were either starved of adenine or heavily irradiated with ultraviolet light, with the aim of preventing them from synthesizing DNA.
J D, Gross, L G, Caro
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Arrest of Bacterial DNA Replication

Annual Review of Microbiology, 1992
The chromosomes of both gram-positive and gram-negative bacteria contain sites that arrest the progression of DNA replication forks. These replication-arrest sites limit the end of the replication cycle to a particular region of the chromosome, called the terminus region.
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Bacterial CpG-DNA Licenses TLR9

2002
The family of Toll-like receptors (TLRs) plays an important role in the innate immune response to pathogens. TLRs sense pathogen associated molecular patterns (PAMP) and lead to the stimulation of immune cells. In man, so far ten members (TLR1-10) have been reported.
S, Bauer, H, Wagner
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Bacterial DNA in Clarkia fossils

Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences, 1991
For the growing number of investigators who study ancient DNA, the most stimulating paper published during 1990 reported the determination of a chloroplast DNA sequence from a plant compression fossil found in a Miocene deposit at Clarkia, Idaho (Golenberg et al. 1990). During August 1990, S.P.
Sidow, A.   +2 more
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DNA uptake during bacterial transformation

Nature Reviews Microbiology, 2004
Naturally competent bacteria are able to take up exogenous DNA and undergo genetic transformation. The transport of DNA from the extracellular milieu into the cytoplasm is a complex process, and requires proteins that are related to those involved in the assembly of type IV pili and type II secretion systems, as well as a DNA translocase complex at the
Inês, Chen, David, Dubnau
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Untangling bacterial DNA topoisomerases functions

Biochemical Society Transactions
Topoisomerases are the main enzymes capable of resolving the topological constraints imposed by DNA transactions such as transcription or replication. All bacteria possess topoisomerases of different types. Although bacteria with circular replicons should encounter similar DNA topology issues, the distribution of topoisomerases varies from one ...
Céline Borde   +2 more
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Preparation of Bacterial Plasmid DNA

Current Protocols in Neuroscience, 1998
AbstractThe protocols in this unit describe methods for preparing bacterial plasmid DNA free from chromosomal DNA. The first is an alkaline lysis miniprep suitable for screening a moderate number of bacterial colonies by restriction endonuclease cleavage and agarose gel electrophoresis.
J, Engebrecht, J S, Heilig, R, Brent
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Bacterial Dna in Mixed Cholesterol Gallstones

American Journal of Gastroenterology, 1999
Numerous investigators have proposed a role for bacteria in biliary lithogenesis. We hypothesized that bacterial DNA is present in gallstones, and that categorical differences exist between gallstone type and the frequency of bacterial sequences.Polymerase chain reaction (PCR) was used to amplify bacterial 16S rRNA and uidA (encoding Escherichia coli ...
Haigh, WG, Tarr, PI, Lee, DK, Lee, SP
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Bacterial DNA strand compositional asymmetry

Trends in Microbiology, 1999
Genes that deviate strongly in codon usage from the average gene but are relatively similar in codon usage to ribosomal protein (RP) genes are viewed as highly expressed22xKarlin, S., Campbell, A.M., and Mrazek, J. Annu. Rev. Genet. 1998; 32: 185–225Crossref | PubMed | Scopus (229)See all References, 23xKarlin, S., Mrazek, J., and Campbell, A.M.
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