Results 191 to 200 of about 506,971 (266)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Fungal contamination, mycotoxins, histamine, and allergen-related immunoreactivity in edible insects and insect-fortified complementary foods. [PDF]

Front Fungal Biol
Imbumi M, Okoth S, Audenaert K, De Steur H, Gellynck X, Tanga CM, De Saeger S, Kimiywe J, Raes K.   +8 more
europepmc   +1 more source

Identification and characterisation of calcitonin receptor isoforms expressed in glioblastoma derived glioma stem and U‐87 MG cells

FEBS Open Bio, EarlyView.
Glioblastoma cells express calcitonin receptor variants (CT receptor isoforms) that may help them survive stress. Using qPCR, transcript‐specific long‐read nanopore sequencing, immunofluorescence co‐localisation and comparative sequence analysis, this study identifies a novel alternatively spliced CALCR transcript that encodes the CTb receptor isoform ...
Pragya Gupta, Sebastian GB Furness, Tahereh Gharbi, Ric De Paoli‐Iseppi, Shweta S. Joshi, Michael Clark, David L. Hare, Peter Wookey   +7 more
wiley   +1 more source

Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank

FEBS Open Bio, EarlyView.
Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer, Pawel Rubach, Zbigniew Dauter, Wojciech Dec, Dariusz Brzezinski, Marta Kulik, Wladek Minor, Mariusz Jaskolski   +7 more
wiley   +1 more source

Nanorulers for Super-Resolution Microscopy. [PDF]

Chembiochem
Beliu G, Szalai AM, Acuna G, Chizhik A, Gallea JI, Enderlein J.   +5 more
europepmc   +1 more source

Glutaminolysis Blockade-Empowered Bimodal Nanodepot for Spatially Complementary Sono-Thermal Ablation via PANoptosis and STING Activation Against Large Tumors. [PDF]

Adv Sci (Weinh)
Liu YM, Qin J, Wu SY, Zhu XZ, Cai YF, Sun PY, Yang H, Wang XY, Li S, Wang D, Zhu HD.   +10 more
europepmc   +1 more source

Linking germline telomere removal to global programmed DNA elimination in <i>Tetrahymena</i> genome differentiation. [PDF]

Elife
Nagao K, Lemoine A, Noto T, Mochizuki K.
europepmc   +1 more source

Dual recognition drives site-directed G-quadruplex stabilization: Oligonucleotide design in G4 ligand-oligonucleotide conjugates. [PDF]

Mol Ther Nucleic Acids
Abrahamsson A, Khwaja S, Chaudhari N, Vertueux S, Berner A, Aasumets K, Kumar C, Stietz L, Baladi T, Dahlén A, Wanrooij S, Chorell E.   +11 more
europepmc   +1 more source

Multilocus DNA Barcoding Resolves Area-Based Genetic Variation in Freshwater Shrimps (<i>Macrobrachium</i> sp. and <i>Caridina</i> sp.) from Saline and Non-Saline Habitats in Northeastern Thailand. [PDF]

Biology (Basel)
Saengprajak J, Pakdeenarong N.
europepmc   +1 more source