Results 121 to 130 of about 860,536 (318)

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

Molecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera, Laura Vela‐Martín, Pablo Fernández‐Navarro, José Luis López‐Lorenzo, Javier Cornago, Pilar Llamas, Eduardo Pérez‐Gómez, José Luis Marín‐Rubio, Manuel Fresno, Javier Santos, José Fernández‐Piqueras, María Villa‐Morales   +11 more
wiley   +1 more source

Environmental DNA analysis of echinoderms and other invertebrates present in the Venice lagoon [PDF]

, 2022
openQuest’elaborato di tesi si basa sul lavoro inerente alla messa a punto di un protocollo sperimentale di DNA ambientale per l’identificazione di echinodermi ed altri invertebrati, a partire da campioni di acqua filtrata prelevati in vari siti della ...
MARTINO, FRANCESCO
core  

Consequences of environmental DNA pooling

, 2020
DNA-based techniques are increasingly used to assess biodiversity both above- and belowground. Most effort has focussed on bioinformatics and sample collection, whereas less is known about the consequences of mixing collected environmental DNA (eDNA), post-extraction and pre-PCR.
Ralph Wainer, Hayley Ridgway, Eirian Jones, Duane Peltzer, Ian Dickie   +4 more
openaire   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

The First International eDNA Workshop in Hong Kong: A beginner's guide for the next‐generation eDNA researcher [PDF]

The field of environmental DNA (eDNA) has rapidly advanced in recent years, providing a non-invasive and time-saving method for assessing biodiversity. The First International Environmental DNA (eDNA) Workshop in Hong Kong was held from 16 to 27 October ...
Hellström, Micaela, Seymour, Mathew, Wang, Zhi, Leray, Matthieu, Moffitt, Jessica, Zeng, Xiaoyi, How, Chun Ming, Guibert, Isis, Jeunen, Gert‐Jan, Ip, Jack Chi Ho, Zhao, Meihong, Elbrect, Vasco, Qian, Cheng, Qin, Xian, Tse, Cham Man, Cutracci, Maxine, Lau, Anthony, Liu, Zifang, Wang, Yifu   +18 more
core   +1 more source

Unveiling the potential of eDNA/eRNA approaches for monitoring the critically endangered Yangtze finless porpoise

Global Ecology and Conservation
Assessing the population distribution and dynamics of the critically endangered Yangtze finless porpoise (Neophocaena asiaeorientalis) is essential for informing conservation strategies.
Juan Tan, Yili Qi, Qing Wang, Xiaowu Chen, Chenhong Li   +4 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

LiBird: A new universal primer enhancing avian environmental DNA metabarcoding

Avian Research
In recent years, global avian diversity has been in continuous decline. Traditional monitoring methods are often constrained by detectability limitations and observational challenges, which makes it difficult to fully characterize community structures ...
Linyan Liang, Yuzhi Wang, Xueqiang Lu, Yongqi Feng, Xunqiang Mo, Dongsheng Zhang, Chenhong Li   +6 more
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source