Results 141 to 150 of about 860,536 (318)

Optimization of pore size and filter material for better enrichment of environmental DNA

Frontiers in Environmental Science
In the study of environmental DNA (eDNA), the rate of water filtration and the amount of DNA obtained are of general interest to researchers. We compared the PCTE filters with different pore sizes in enriching total DNA and fish eDNA from water samples ...
Qianqian Liu, Qianqian Liu, Juan Tan, Juan Tan, Juan Tan, Min Wang, Ni Xin, Ni Xin, Rui Qi, Hui Wang, Hui Wang   +10 more
doaj   +1 more source

From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care

Molecular Oncology, EarlyView.
Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard, Flavie Bénard, Eva Billat, Margaux Le Guyon, Victoria Maltret, Laura Merlet, Chloé Astrid Walter, Tony Avril, Eric Chevet   +8 more
wiley   +1 more source

qPCR‐Based Environmental DNA (eDNA) Detection of Cryptic Arboreal Species Interaction With Artificial Habitat Structures

Environmental DNA
Effective restoration of anthropogenically impacted sites requires continued monitoring of faunal species return, but restoration sites often lack mature habitat structures that many species rely on.
Austin M. Guthrie, Christine E. Cooper, Philip W. Bateman, Mieke van derHeyde, Paul Bullock, Paul Nevill   +5 more
doaj   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Development of a molecular tool to identify brown bullhead catfish (Ameiurus nebulosus) from environmental DNA in water [PDF]

, 2020
The aim of this work was to develop a molecular tool to positively identify brown bullhead catfish using environmental DNA (eDNA) that is suspended within the water column. The project had five main objectives: 1) to develop a protocol for the collection
Hicks, Brendan J., Cursons, Ray
core  

Interferon beta drives therapy resistance in a patient‐derived model of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant, Tise Suzuki, Kiera McGivney, V. S. S. Abhinav Ayyadevara, Sharon Asariah, Jay Deng, Ethan Nyein, Jacqueline Coats, Gary Yu, Yevgeniya J. Ioffe, Christian Hurtz, Juli J. Unternaehrer   +11 more
wiley   +1 more source

Far away from home? Ancient DNA shows the presence of bicolored shrew (Crocidura leucodon) in Bronze Age Denmark

Ecology and Evolution
An excavation of an Early Iron Age village near Aalborg in Denmark uncovered the jaws and skull fragments from a small mammal that were morphologically identified to the genus Crocidura (white‐toothed shrews).
Mahsa Mousavi‐Derazmahalleh, Niels Haue, Marie Kanstrup, Jørgen T. Laursen, Sherralee S. Lukehurst, Jacob Kveiborg, Morten E. Allentoft   +6 more
doaj   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

Molecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla, Jyoti Lamichhane, Cameron Lewis, Peter Breslin, Jiwang Zhang   +4 more
wiley   +1 more source

Assessment of Bacterial Community Structure, Associated Functional Role, and Water Health in Full-Scale Municipal Wastewater Treatment Plants

Toxics
The present study collected wastewater samples from fourteen (14) full-scale wastewater treatment plants (WWTPs) at different treatment stages, namely, primary, secondary, and tertiary, to understand the impact of WWTP processes on the bacterial ...
Inderjeet Tyagi, Kaomud Tyagi, Faheem Ahamad, Rakesh Bhutiani, Vikas Kumar   +4 more
doaj   +1 more source

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source