Results 141 to 150 of about 1,505,314 (311)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Decoding Biodiversity in Baiyangdian Lake: A DNA Barcode Reference Library for Aquatic Insects

open access: yesInsects
Freshwater ecosystems are among the most vulnerable habitats worldwide, and reliable biodiversity assessment is essential for their conservation. Baiyangdian Lake, the largest freshwater lake in northern China, has undergone severe ecological degradation
Ya-Jun Qiao   +8 more
doaj   +1 more source

Screening of micro-organisms for Venturia inaequalis control by means of DGGE [PDF]

open access: yes, 2006
Venturia inaequalis causes apple scab. The control of the disease in organic apple production depends on the use of copper which will be restricted in future for environmental reasons.
Köhl, Jürgen   +2 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Environmental DNA (e-DNA) extraction from soil v1

open access: yes
Soil harbors diverse microorganisms, including fungi that play crucial environmental roles but can also harm plants, animals, and humans through infections or spore exposure. In 2022, the WHO released several pathogenic fungi, including Fusarium group, Mucorales and Eumycetoma agents, which are prevalent in Thailand's agricultural soils and have caused
Nuttapon Pombubpa   +5 more
openaire   +1 more source

Insights into a long life without cancer: The case of the bowhead whale

open access: yesMolecular Oncology, EarlyView.
Long‐lived, large‐bodied organisms have evolved powerful anticancer mechanisms that preserve cellular and tissue integrity across extended lifespans. A recent study by Firsanov et al. shows that greater genome stability is a key factor underlying the remarkable longevity and cancer resistance of one such species, the bowhead whale.
Inés Paniagua, Johanna A. Joyce
wiley   +1 more source

Validation of an eDNA‐based workflow for monitoring inter‐ and intra‐specific CytB haplotype diversity of alpine amphibians

open access: yesEnvironmental DNA
Environmental DNA (eDNA) analysis is a promising tool for monitoring wild animal populations and, more recently, their genetic variability. In this study, we used the mitochondrial Cytochrome B gene to develop and apply new eDNA metabarcoding assays ...
Lucia Zanovello   +8 more
doaj   +1 more source

The impact of molecular biology on assessment of water quality: advantages and limitations of current techniques [PDF]

open access: yes, 1997
The advent of molecular biology has had a dramatic impact on all aspects of biology, not least applied microbial ecology. Microbiological testing of water has traditionally depended largely on culture techniques.
Saunders, J.R., Saunders, V.A.
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

The unseen world: environmental microbial sequencing and identification methods for ecologists [PDF]

open access: yes, 2014
Archaea, bacteria, microeukaryotes, and the viruses that infect them (collectively “microorganisms”) are foundational components of all ecosystems, inhabiting almost every imaginable environment and comprising the majority of the planet’s organismal and ...
Aronson, Emma   +4 more
core   +1 more source

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