Results 21 to 30 of about 201,987 (218)

Core histones govern echinocandin susceptibility in Candida glabrata

Microbiology Spectrum
The dynamic chromatin structure regulates many biological processes including gene expression, DNA repair, and genome stability in eukaryotic cells.
Aditi Pareek, Rupinder Kaur
doaj   +1 more source

Internal Transcribed Spacer (ITS) as Dna Barcoding to Identify Fungal Species: a Review

Squalen, 2016
Despite the fact that fungi are important sources of both bioactive compounds and mycotoxins, and that they are very ubiquitous in our environment, their species identification is hampered by incomplete and often unclear literature.
Nurrahmi Dewi Fajarningsih
doaj   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

DNA- and RNA- Derived Fungal Communities in Subsurface Aquifers Only Partly Overlap but React Similarly to Environmental Factors

Microorganisms, 2019
Recent advances in high-throughput sequencing (HTS) technologies have revolutionized our understanding of microbial diversity and composition in relation to their environment.
Ali Nawaz, Witoon Purahong, Martina Herrmann, Kirsten Küsel, François Buscot, Tesfaye Wubet   +5 more
doaj   +1 more source

Evaluating the Impact of DNA Extraction Method on the Representation of Human Oral Bacterial and Fungal Communities. [PDF]

PLoS ONE, 2017
The application of high-throughput, next-generation sequencing technologies has greatly improved our understanding of the human oral microbiome. While deciphering this diverse microbial community using such approaches is more accurate than traditional ...
Anna Vesty, Kristi Biswas, Michael W Taylor, Kim Gear, Richard G Douglas   +4 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

SWI/SNF complex-mediated chromatin remodeling in Candida glabrata promotes immune evasion

iScience
Summary: Immune evasion is critical for fungal virulence. However, how the human opportunistic pathogen Candida glabrata (Cg) accomplishes this is unknown. Here, we present the first genome-wide nucleosome map of the macrophage-internalized Cg consisting
Kundan Kumar, Aditi Pareek, Rupinder Kaur   +2 more
doaj   +1 more source

Lipid Nanoparticle Co‐Delivery of mRNA and a Small Molecule Drug for Oral Cancer Chemoimmunotherapy

Advanced Materials, EarlyView.
Co‐encapsulation of p53 mRNA and the small molecule ciclopirox within a lipid nanoparticle yields an all‐in‐one chemoimmunotherapy for oral squamous cell carcinoma. The platform engages caspase‐driven apoptosis in cancer cells while repolarizing tumor‐associated macrophages, achieving tumor reduction in both p53‐susceptible and p53‐resistant models and
Marshall S. Padilla, Jacqueline J. Li, Qunzhou Zhang, Korey Patwari, Shihong Shi, Hannah M. Yamagata, Ryann A. Joseph, Briyanna N. Hymms, Sridatta V. Teerdhala, Emily Fitzgerald, Ori Z. Chalom, Kushol Gupta, Mohamad‐Gabriel Alameh, Drew Weissman, Anh D. Le, Michael J. Mitchell   +15 more
wiley   +1 more source

Protocol for determination of phosphatidylinositol 3-phosphate levels and localization in Candida glabrata by confocal microscopy

STAR Protocols
Summary: Phosphatidylinositol 3-phosphate (PI3P) levels govern membrane trafficking in Candida glabrata. Here, we present a confocal imaging-based protocol for PI3P localization analysis using the GFP-FYVE (found in Fab1, YOTB, Vac1, and EEA1) fusion ...
Fizza Askari, Rupinder Kaur
doaj   +1 more source

Monitoring Fungal Communities With the Global Spore Sampling Project

Frontiers in Ecology and Evolution, 2020
The kingdom Fungi is a megadiverse group represented in all ecosystem types. The global diversity and distribution of fungal taxa are poorly known, in part due to the limitations related to traditional fruit-body survey methods.
Otso Ovaskainen, Otso Ovaskainen, Nerea Abrego, Panu Somervuo, Isabella Palorinne, Bess Hardwick, Bess Hardwick, Juha-Matti Pitkänen, Juha-Matti Pitkänen, Nigel R. Andrew, Pascal A. Niklaus, Niels Martin Schmidt, Niels Martin Schmidt, Sebastian Seibold, Sebastian Seibold, Juliane Vogt, Evgeny V. Zakharov, Paul D. N. Hebert, Tomas Roslin, Tomas Roslin, Natalia V. Ivanova   +20 more
doaj   +1 more source