Results 51 to 60 of about 2,149,898 (257)

Engineering Antigen Density on M13 Bacteriophage for Personalized Nanovaccine

Advanced Healthcare Materials, EarlyView.
Increasing antigen density on the phage capsid impacts phage uptake and antigen cross‐presentation by antigen‐presenting cells, leading to enhanced activation of antitumor CD8+ T cells in the draining lymph nodes. These activated CD8+ T cells subsequently recognize the antigen‐expressing tumors and mediate their specific cytotoxic killing, thereby ...
Shengnan Huang, Allison Madow, Jack Rudrum, Huaiyao Peng, Hao Nghi Luu, Peiyan Dong, Jifa Qi, Angela M. Belcher   +7 more
wiley   +1 more source

Fungal entomopathogens: new insights on their ecology [PDF]

, 2009
An important mechanism for insect pest control should be the use of fungal entomopathogens. Even though these organisms have been studied for more than 100 y, their effective use in the field remains elusive.
Vega, F. E., Maniania, N. K., Goettel, Mark S., Roy, H. E., Goettel, M. S., Monzón, Arnulfo, Keller, S., Rangel, D. E. N., Chandler, Dave, Jackson, Mark A., Rangel, Drauzio E.N., Keller, Siegfried, Roy, Helen, Koike, M., Blackwell, M. S. A., Monzon, A., Chandler, David, Chandler, D., Keller, Siegrried, Blackwell, Meredith, Maniania, Nguya K., Pell, Judith K., Pell, J. K., Vega, Fernando E., Jackson, M. A., Ownley, Bonnie H., Koike, Masanori, Roy, Helen E., Ownley, B. H., Pell, Judith, Blackwell, Martin   +30 more
core   +1 more source

Succession of wood-inhabiting fungal communities [PDF]

, 2013
Dead wood constitutes an important substrate for biodiversity in boreal forests. As the wood decays, fungal communities develop and species associations are formed.
Ottosson, Elisabet
core   +1 more source

Protocol for determination of phosphatidylinositol 3-phosphate levels and localization in Candida glabrata by confocal microscopy

STAR Protocols
Summary: Phosphatidylinositol 3-phosphate (PI3P) levels govern membrane trafficking in Candida glabrata. Here, we present a confocal imaging-based protocol for PI3P localization analysis using the GFP-FYVE (found in Fab1, YOTB, Vac1, and EEA1) fusion ...
Fizza Askari, Rupinder Kaur
doaj   +1 more source

Evaluating the Impact of DNA Extraction Method on the Representation of Human Oral Bacterial and Fungal Communities. [PDF]

PLoS ONE, 2017
The application of high-throughput, next-generation sequencing technologies has greatly improved our understanding of the human oral microbiome. While deciphering this diverse microbial community using such approaches is more accurate than traditional ...
Anna Vesty, Kristi Biswas, Michael W Taylor, Kim Gear, Richard G Douglas   +4 more
doaj   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

Advanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang, Yupo Wu, Jiachang Hou, Lixia Gao, Longqi Pan, Cuicui Shen, Chuanji Zhao, Feng Gao, Yi Zhang, Li Ren, Xiaoping Fang, Xiaoling Dun, Shengyi Liu, Lijiang Liu   +13 more
wiley   +1 more source

Methods for integrated air sampling and DNA analysis for detection of airborne fungal spores

, 2001
Integrated air sampling and PCR-based methods for detecting airborne fungal spores, using Penicillium roqueforti as a model fungus, are described. P. roqueforti spores were collected directly into Eppendorf
Roger H. Williams, Williams, R. H., Ward, E., McCartney, H. A., Elaine Ward, H. Alastair McCartney   +5 more
core   +1 more source

A quantitative PCR approach to determine gene copy number [PDF]

, 2008
Here, we report on the use of quantitative PCR (qPCR) to determine gene copy number in filamentous fungi. Using the sequenced dothideomycete Stagonospora nodorum, qPCR was used to unequivocally confirm the presence of single, two and three copy regions ...
Hane, J., Oliver, Richard, Peter S. Solomon, Solomon, Peter S., Ipcho, S., Hane, J.K., Solomon, P., Ipcho, Simon V.S., Tan, K.C., Ipcho, S.V.S., Tan, Kar-Chun, James K. Hane, Oliver, R.P., Richard P. Oliver, Hane, James K., Kar-Chun Tan, Oliver, Richard P., Solomon, P.S., Simon V.S. Ipcho   +18 more
core   +1 more source

Aspartyl proteases target host actin nucleator complex protein to limit epithelial innate immunity

EMBO Reports
Epithelial-immune cell communication is pivotal to control microbial infections. We show that glycosylphosphatidylinositol-linked aspartyl proteases (Yapsins) of the human opportunistic pathogenic yeast Candida glabrata (Cg) thwart epithelial cell (EC ...
Sandip Patra, Rupinder Kaur
doaj   +1 more source

Reusable Biosensor for Easy RNA Detection from Unfiltered Saliva

Sensors
Biosensors are transforming point-of-care diagnostics by simplifying the detection process and enabling rapid, accurate testing. This study introduces a novel, reusable biosensor designed for direct viral RNA detection from unfiltered saliva, targeting ...
Paweł Wityk, Agata Terebieniec, Robert Nowak, Jacek Łubiński, Martyna Mroczyńska-Szeląg, Tomasz Wityk, Dorota Kostrzewa-Nowak   +6 more
doaj   +1 more source