Results 61 to 70 of about 2,856,737 (303)

Core histones govern echinocandin susceptibility in Candida glabrata

Microbiology Spectrum
The dynamic chromatin structure regulates many biological processes including gene expression, DNA repair, and genome stability in eukaryotic cells.
Aditi Pareek, Rupinder Kaur
doaj   +1 more source

DNA- and RNA- Derived Fungal Communities in Subsurface Aquifers Only Partly Overlap but React Similarly to Environmental Factors

Microorganisms, 2019
Recent advances in high-throughput sequencing (HTS) technologies have revolutionized our understanding of microbial diversity and composition in relation to their environment.
Ali Nawaz, Witoon Purahong, Martina Herrmann, Kirsten Küsel, François Buscot, Tesfaye Wubet   +5 more
doaj   +1 more source

Spatial structure of fungal DNA assemblages revealed with eDNA metabarcoding in a forest river network in western Japan [PDF]

Metabarcoding and Metagenomics, 2019
Growing evidence has revealed high diversity and spatial heterogeneity of fungal communities in local habitats of terrestrial ecosystems. Recently, the analysis of environmental DNA has been undertaken to study the biodiversity of organisms, such as ...
Shunsuke Matsuoka, Yoriko Sugiyama, Hirotoshi Sato, Izumi Katano, Ken Harada, Hideyuki Doi   +5 more
doaj   +3 more sources

Liquid biopsy for infectious diseases: Sequencing of cell-free plasma to detect pathogen DNA in patients with invasive fungal disease

bioRxiv, 2018
Diagnosis of life-threatening deep-seated infections currently requires invasive sampling of the infected tissue to provide a microbiologic diagnosis. These procedures can lead to high morbidity in patients and add to healthcare costs. Here we describe a
David K. Hong, T. Blauwkamp, Mickey Kertesz, S. Bercovici, Cynthia Y. Truong, N. Banaei   +5 more
semanticscholar   +1 more source

A pan-cancer mycobiome analysis reveals fungal involvement in gastrointestinal and lung tumors

Cell, 2022
SUMMARY Fungal microorganisms (mycobiota) comprise a small but immunoreactive component of the human microbiome, yet little is known about their role in human cancers. Pan-cancer analysis of multiple body sites revealed tumor-specific mycobiomes at up to
Anders B. Dohlman, J. Klug, Marissa Mesko, I. H. Gao, S. Lipkin, Xiling Shen, I. Iliev   +6 more
semanticscholar   +1 more source

General Fungal DNA Extraction v2

, 2023
This is a routine protocol for extracting DNA from various fungi. This extraction method is suitable for follow-up molecular work such as PCR amplification.
Angie Macias, Matthew T Kasson, Brian Lovett   +2 more
openaire   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Rad53- and Chk1-Dependent DNA Damage Response Pathways Cooperatively Promote Fungal Pathogenesis and Modulate Antifungal Drug Susceptibility

mBio, 2019
Genome instability is detrimental for living things because it induces genetic disorder diseases and transfers incorrect genome information to descendants.
Kwang-Woo Jung, Yeonseon Lee, E. Huh, Soo Chan Lee, Sangyong Lim, Yong-Sun Bahn   +5 more
semanticscholar   +1 more source

SWI/SNF complex-mediated chromatin remodeling in Candida glabrata promotes immune evasion

iScience
Summary: Immune evasion is critical for fungal virulence. However, how the human opportunistic pathogen Candida glabrata (Cg) accomplishes this is unknown. Here, we present the first genome-wide nucleosome map of the macrophage-internalized Cg consisting
Kundan Kumar, Aditi Pareek, Rupinder Kaur   +2 more
doaj   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source