Results 81 to 90 of about 323,377 (241)

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

Aggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky, Olesya V. Stepanenko, Olga V. Stepanenko, Anna I. Sulatskaya   +3 more
wiley   +1 more source

The biotechnology of higher fungi - current state and perspectives [PDF]

, 2014
This review article concisely describes methodology of biotechnological processes with the use of cultures of higher fungi, their application in bioremediation and to obtain biologically active preparations.
Turło, Jadwiga
core   +1 more source

Identification of bioactive compounds and molecular targets of Fuke Huahuang formulation to treat vaginitis

Animal Models and Experimental Medicine, EarlyView.
Fuke Huahuang formulation (FHF) is used to treat vaginitis, and it exerts a promising anti‐inflammatory effect in clinical use. However, the detailed components and mechanisms of FHF for treating vaginitis remain unreported, and further preclinical evaluation is required to reveal its potential pharmacological activities against vaginitis.
Huiyu Liu, Jie Mo, Cheng Liang, Qingting Chen, Bin Yang, Jiaqi Liu   +5 more
wiley   +1 more source

GC Content of the Rumen Fungal DNA [PDF]

Annales de Zootechnie, 1995
Kostyukovsky, V, Kohda, C, Nakai, Y, Ando, T, Inamoto, T, Ogimoto, K   +5 more
openaire   +4 more sources

DNA damage induced by hydroquinone can be prevented by fungal detoxification

Toxicology Reports, 2014
Hydroquinone is a benzene metabolite with a wide range of industrial applications, which has potential for widespread human exposure; however, the toxicity of hydroquinone on human cells remains unclear. The aims of this study are to investigate the cytotoxicity and genotoxicity of hydroquinone in human primary fibroblasts and human colon cancer cells (
Pereira, Pedro, Enguita, Francisco J., Ferreira, João, Leitão, Ana Lúcia   +3 more
openaire   +5 more sources

Bioinspired Cationic Antimicrobial Polymers

Angewandte Chemie International Edition, EarlyView.
A review about membrane active cationic polymers with antimicrobial properties. A focus is laid on polymeric architecture, stimuli‐responsive antimicrobial polymers, as well as synergistic effects of polymers, and other compounds. Abstract Antibiotics are an essential tool of modern medicine, which is critically endangered by the spread of ...
Heliya Javadi, Anne‐Catherine Lehnen, Matthias Hartlieb   +2 more
wiley   +1 more source

Unraveling the ancient fungal DNA from the Iceman gut

BMC Genomics
AbstractHere, we explore the possible ancient fungal species in the gut of Ötzi, the Iceman, a naturally mummified human found in the Tyrolean Alps (border between Italy and Austria). While ancient DNA (aDNA) has been extensively used to study human, animal, and plant evolution, this research focuses on ancient microbial diversity, specifically fungi ...
Nikolay Oskolkov, Anna Sandionigi, Anders Göterström, Fabiana Canini, Benedetta Turchetti, Laura Zucconi, Tanja Mimmo, Pietro Buzzini, Luigimaria Borruso   +8 more
openaire   +2 more sources

Antibiotic Sensitivity of Vibrio spp. and Shewanella algae Isolated From Brood and Egg of Mud Crab Hatchery

Animal Research and One Health, EarlyView.
Vibrio alginolyticus NBRC 15630, Vibrio parahaemolyticus ATCC 17802, Shewanella algae DW01, and Shewanella algae ATCC 51192 bacterial strains were found in the Mud crab brood and egg samples. All isolates were found to be sensitive to cefotaxime, chloramphenicol, gentamicin, and nitrofurantoin antibiotics.
Abul Farah Md. Hasanuzzaman, Nurunnahar Nadira, Anup Sardar, Sabia Islam   +3 more
wiley   +1 more source

A rust fungal effector binds plant DNA and modulates transcription

Scientific Reports, 2018
AbstractThe basidiomycete Melampsora larici-populina causes poplar rust disease by invading leaf tissues and secreting effector proteins through specialized infection structures known as haustoria. The mechanisms by which rust effectors promote pathogen virulence are poorly understood.
Cécile Lorrain, Isabel Desgagné-Penix, Benjamin Petre, Benjamin Petre, Bulbul Ahmed, Hugo Germain, Ingrid Benerice Sanchez, Ingrid Benerice Sanchez, Mélodie B. Plourde, Sébastien Duplessis, Karen Cristine Gonçalves dos Santos   +10 more
openaire   +7 more sources

Emergence of Staphylococcus aureus Resistance to Antimicrobial Peptides Nisin, NZ2114 and Bacitracin Involves Multiple Phenotypic Changes

Animal Research and One Health, EarlyView.
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao, Xingyuan Ma, Ping Tian, Lianbin Li, Zafir Muhammad, Xiaokun Wang, Xuemei Xue, Jinhe Xiao, Liangjun Zheng, F. A. El‐Gohary, Xin Zhao, Junning Pu, Huping Xue   +12 more
wiley   +1 more source