Results 11 to 20 of about 171,193 (280)
Plant viral intergenic DNA sequence repeats with transcription enhancing activity [PDF]
Virology Journal, 2005 Background The geminivirus and nanovirus families of DNA plant viruses have proved to be a fertile source of viral genomic sequences, clearly demonstrated by the large number of sequence entries within public DNA sequence databases.
Cazzonelli Christopher I +2 more
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Structure of the intergenic spacers in chicken ribosomal DNA [PDF]
Genetics Selection Evolution, 2019 Background Ribosomal DNA (rDNA) repeats are situated in the nucleolus organizer regions (NOR) of chromosomes and transcribed into rRNA for ribosome biogenesis. Thus, they are an essential component of eukaryotic genomes. rDNA repeat units consist of rRNA
Alexander Dyomin +10 more
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A discrete class of intergenic DNA dictates meiotic DNA break hotspots in fission yeast.
PLoS Genetics, 2007 Meiotic recombination is initiated by DNA double-strand breaks (DSBs) made by Spo11 (Rec12 in fission yeast), which becomes covalently linked to the DSB ends.
Gareth A Cromie +5 more
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Arabidopsis DNA Replication Initiates in Intergenic, AT-Rich Open Chromatin [PDF]
Plant Physiology, 2020 The selection and firing of DNA replication origins play key roles in ensuring that eukaryotes accurately replicate their genomes. This process is not well documented in plants due in large measure to difficulties in working with plant systems. We developed a new functional assay to label and map very early replicating loci that must, by definition ...
Emily Wheeler +11 more
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Statistical analysis of gene and intergenic DNA sequences [PDF]
Physica A: Statistical Mechanics and its Applications, 2004 Much of the on-going statistical analysis of DNA sequences is focused on the estimation of characteristics of coding and non-coding regions that would possibly allow discrimination of these regions. In the current approach, we concentrate specifically on genes and intergenic regions.
Kugiumtzis, D., Provata, A.
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The regulatory content of intergenic DNA shapes genome architecture [PDF]
Genome Biology, 2004 Factors affecting the organization and spacing of functionally unrelated genes in metazoan genomes are not well understood. Because of the vast size of a typical metazoan genome compared to known regulatory and protein-coding regions, functional DNA is generally considered to have a negligible impact on gene spacing and genome organization.
Craig E, Nelson +2 more
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Involvement of DNA curvature in intergenic regions of prokaryotes [PDF]
Nucleic Acids Research, 2006 It is known that DNA curvature plays a certain role in gene regulation. The distribution of curved DNA in promoter regions is evolutionarily preserved, and it is mainly determined by temperature of habitat. However, very little is known on the distribution of DNA curvature in termination sites.
Kozobay-Avraham, Limor +2 more
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CtBP levels control intergenic transcripts, PHO/YY1 DNA binding, and PcG recruitment to DNA [PDF]
Journal of Cellular Biochemistry, 2010 AbstractCarboxy‐terminal binding protein (CtBP) is a well‐known corepressor of several DNA binding transcription factors in Drosophila as well as in mammals. CtBP is implicated in Polycomb Group (PcG) complex‐mediated transcriptional repression because it can bind to some PcG proteins, and mutation of the ctbp gene in flies results in lost PcG protein ...
Arindam, Basu, Michael L, Atchison
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Patterns of Evolutionary Constraints in Intronic and Intergenic DNA of Drosophila [PDF]
Genome Research, 2004 We develop methods to infer levels of evolutionary constraints in the genome by comparing rates of nucleotide substitution in noncoding DNA with rates predicted from rates of synonymous site evolution in adjacent genes or other putatively neutrally evolving sites, while accounting for differences in base composition.
Halligan, Daniel +3 more
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The long non-coding RNA Dali is an epigenetic regulator of neural differentiation
eLife, 2014 Many intergenic long noncoding RNA (lncRNA) loci regulate the expression of adjacent protein coding genes. Less clear is whether intergenic lncRNAs commonly regulate transcription by modulating chromatin at genomically distant loci.
Vladislava Chalei +6 more
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