Results 81 to 90 of about 171,193 (280)

Non-extensive Trends in the Size Distribution of Coding and Non-coding DNA Sequences in the Human Genome

, 2005
We study the primary DNA structure of four of the most completely sequenced human chromosomes (including chromosome 19 which is the most dense in coding), using Non-extensive Statistics.
Oikonomou, Th., Provata, A.
core   +2 more sources

Genome-wide DNA hypomethylation and RNA:DNA hybrid accumulation in Aicardi-Goutières syndrome. [PDF]

, 2015
Aicardi-Goutières syndrome (AGS) is a severe childhood inflammatory disorder that shows clinical and genetic overlap with systemic lupus erythematosus (SLE).
Chédin, Frédéric, Hartono, Stella R, Lim, Yoong Wearn, Sanz, Lionel A, Xu, Xiaoqin   +4 more
core   +2 more sources

Flipping the Switch: MeCP2‐Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation

Advanced Science, EarlyView.
Stroke‐induced lactate accumulation promotes p300‐mediated lactylation of methyl‐CpG binding protein 2 (MeCP2) at lysine 210, which reprograms microglial metabolism toward glycolysis and activates the hexokinase 2 (HK2)/mTOR axis. This cascade promotes proinflammatory responses and impairs neurofunctional outcomes.
Zengyu Zhang, Shanshan Huang, Yong Wang, Zhiwen Jiang, Zhuohang Liu, Chenran Wang, Rong Ji, Yiwen Yuan, Xueyu Mao, Kaicheng Yang, Huicong Niu, Yanqin Gao, Jing Zhao   +12 more
wiley   +1 more source

Novel Bacteriocinogenic Lactobacillus plantarum Strains and Their Differentiation by Sequence Analysis of 16S rDNA, 16S-23S and 23S-5S Intergenic Spacer Regions and Randomly Amplified Polymorphic DNA Analysis

Food Technology and Biotechnology, 2010
Six strains of bacteriocinogenic Lactobacillus plantarum (TL1, RG11, RS5, UL4, RG14 and RI11) isolated from Malaysian foods were investigated for their structural bacteriocin genes.
Morteza Shojaei Moghadam, Thean Chor Leow, Raha Abdul Rahim, Teck Chwen Loh, Hooi Ling Foo   +4 more
doaj  

Nanopore sequencing and multiomics reveal predictable non-coding RNA activation in DNA methylation deficient Arabidopsis thaliana

Communications Biology
Long intergenic non-coding RNAs (lincRNAs) are regulatory transcripts from intergenic regions with diverse expression patterns, but whether the activation of lincRNA is widespread and predictable remains unclear.
Wanghong Shi, Luyao Wang, Na Zhou, Mengke Zhang, Yupeng Hao, Ke Nie, Xueying Guan, Ting Zhao   +7 more
doaj   +1 more source

Evolutionary relationships in Panicoid grasses based on plastome phylogenomics (Panicoideae; Poaceae) [PDF]

, 2016
Background: Panicoideae are the second largest subfamily in Poaceae (grass family), with 212 genera and approximately 3316 species. Previous studies have begun to reveal relationships within the subfamily, but largely lack resolution and/or robust ...
Burke, Sean V., Clark, Lynn G., Craine, Joseph M., Duvall, Melvin R., Edger, Patrick P., Kelchner, Scot A., Mayfield Jones, Dustin, Pires, J. Chris, Wysocki, William P., Zuloaga, Fernando Omar   +9 more
core   +2 more sources

Sensitivity of intergenic regions of yeast mitochondrial DNA to single‐strand‐specific nucleases [PDF]

FEBS Letters, 1988
The reactivity of mitochondrial DNA (mtDNA) sequences from Torulopsis glabrata and Saccharomyces cerevisiae towards single‐strand‐specific nucleases has been examined. AT‐rich stretches located in intergenic sequences from both yeasts were cleaved by nucleases when the sequences were contained in supercoiled plasmid DNA. In particular ori/rep sequences
openaire   +2 more sources

Nap1L4a Cooperates with Scl/Klf1 to Recruit H2A.Z in Mediating Interactions Among Cis‐Regulatory Elements and Transcription Required for Primitive Erythropoiesis in Zebrafish

Advanced Science, EarlyView.
Nap1l4a is required in erythropoiesis and hypoxia responses via physical interaction with Klf1 and Scl to recruit the histone variant H2A.Z. This facilitates its associated cis‐regulatory element (CRE) remodeling and the consequent chromatin assembly, and activates the transcription of erythroid lineage‐specific genes.
JiaHao Shi, FuMing Lai, Zheng Shen, XiaoYan Zhang, HanFei Wang, WenYe Liu, YunLong Wang, KuanYu Li, GuoLiang Li, YaPing Fang, Jing‐Xia Liu   +10 more
wiley   +1 more source

Independent modulation of individual genomic component transcription and a cis-acting element related to high transcriptional activity in a multipartite DNA virus

BMC Genomics, 2019
Background The genome of Banana bunchy top virus (BBTV) consists of at least six circular, single-stranded DNA components of ~ 1 kb in length. Some BBTV isolates may also carry satellite DNA molecules that are not essential for BBTV infection.
Nai-Tong Yu, Hui-Min Xie, Yu-Liang Zhang, Jian-Hua Wang, Zhongguo Xiong, Zhi-Xin Liu   +5 more
doaj   +1 more source

Tertiary-Treated Municipal Wastewater is a Significant Point Source of Antibiotic Resistance Genes Into Duluth-Superior Harbor [PDF]

, 2011
In this study, the impact of tertiary-treated municipal wastewater on the quantity of several antibiotic resistance determinants in Duluth-Superior Harbor was investigated by collecting surface water and sediment samples from 13 locations in Duluth ...
Allen H. K., Alonso A., Amann R. I., Andersson D. I., Arthurson V., Auerbach E. A., Benson D. A., Berhardt A. E., Berhardt A. E., Canton R., Cardinale M., Chopra I., Cotner J. B., David T. Tan, Davies J., Diehl D. L., D’Costa V. M., Ghosh S., Graham D. W., Jessica J. Eichmiller, Levy S. B., Levy S. B., Ling L. L., Lipsitch M., Martínez J., Merlin C., Mi Yan, Moura A., Munir M., Nelson D. K., Novo A., Patrick J. McNamara, Pruden A., Ramsden S. J., Sambrook J., Seurinck S., Smith D. L., Sommer M. O. A., Staley J. T., Storteboom H., Tchobanoglous G., Thioulouse J., Thompson J. D., Timothy M. LaPara, Tucker R. Burch, Xi C., Yi L., Zhang T., Zhang X., Zhang X.-X.   +49 more
core   +3 more sources