Results 81 to 90 of about 117,531 (301)

Nanopore sequencing and multiomics reveal predictable non-coding RNA activation in DNA methylation deficient Arabidopsis thaliana

Communications Biology
Long intergenic non-coding RNAs (lincRNAs) are regulatory transcripts from intergenic regions with diverse expression patterns, but whether the activation of lincRNA is widespread and predictable remains unclear.
Wanghong Shi, Luyao Wang, Na Zhou, Mengke Zhang, Yupeng Hao, Ke Nie, Xueying Guan, Ting Zhao   +7 more
doaj   +1 more source

The complete mitochondrial genome of sugarcane (Saccharum spp.) variety FN15

Mitochondrial DNA. Part B. Resources, 2020
The complete mitogenome of Saccharum spp. hybrid FN15 was successfully sequenced. It contains two distinct circular chromosomes, Chromosome 1 and Chromosome 2.
Xiaolan Liu, Ze Yin, Ying Liu, Zhu Li, Mingli Yan, Youxiong Que, Liping Xu, Dinggang Zhou   +7 more
doaj   +1 more source

Stage‐Specific H3K14 and H3K23 Succinylation Orchestrates Insect Metamorphosis and Oogenesis

Advanced Science, EarlyView.
Stage‐specific succinylation of histone H3 at lysine 14 and 23 differentially controls insect metamorphosis and oogenesis through distinct GPCR‐PKC signaling cascades, revealing an evolutionarily conserved epigenetic mechanism that coordinates key life‐history traits.
Yu‐Pu Jing, Lunjie Li, Libin Yang, Lin‐Jie Zhang, Qiang Yan, Ci Zhang, Zanrong Wen, Guangze Yu, Qian Li, Shutang Zhou   +9 more
wiley   +1 more source

Novel Bacteriocinogenic Lactobacillus plantarum Strains and Their Differentiation by Sequence Analysis of 16S rDNA, 16S-23S and 23S-5S Intergenic Spacer Regions and Randomly Amplified Polymorphic DNA Analysis

Food Technology and Biotechnology, 2010
Six strains of bacteriocinogenic Lactobacillus plantarum (TL1, RG11, RS5, UL4, RG14 and RI11) isolated from Malaysian foods were investigated for their structural bacteriocin genes.
Morteza Shojaei Moghadam, Thean Chor Leow, Raha Abdul Rahim, Teck Chwen Loh, Hooi Ling Foo   +4 more
doaj  

Independent modulation of individual genomic component transcription and a cis-acting element related to high transcriptional activity in a multipartite DNA virus

BMC Genomics, 2019
Background The genome of Banana bunchy top virus (BBTV) consists of at least six circular, single-stranded DNA components of ~ 1 kb in length. Some BBTV isolates may also carry satellite DNA molecules that are not essential for BBTV infection.
Nai-Tong Yu, Hui-Min Xie, Yu-Liang Zhang, Jian-Hua Wang, Zhongguo Xiong, Zhi-Xin Liu   +5 more
doaj   +1 more source

Decoupling of DNA methylation and activity of intergenic LINE-1 promoters in colorectal cancer [PDF]

Epigenetics, 2017
Hypomethylation of LINE-1 repeats in cancer has been proposed as the main mechanism behind their activation; this assumption, however, was based on findings from early studies that were biased toward young and transpositionally active elements. Here, we investigate the relationship between methylation of 2 intergenic, transpositionally inactive LINE-1 ...
Natasha Vafadar-Isfahani, Christina Parr, Lara E. McMillan, Juliane Sanner, Zhao Yeo, Stephen Saddington, Oliver Peacock, Hazel A. Cruickshanks, Richard R. Meehan, Jonathan N. Lund, Cristina Tufarelli   +10 more
openaire   +5 more sources

The strong enhancer element in the immediate early region of the human cytomegalovirus genome [PDF]

, 1985
The human cytomegalovirus (HCMV), a member of the herpesvirus group, was found to possess a strong transcription enhancer in the immediate early gene region. Co-transfection of enhancerless SV40 DNA with randomly fragmented HCMV DNA yielded two SV40-
Boshart, Michael, Schaffner, Walter, Weber, Frank, Dorsch-Häsler, Karoline, Jahn, Gerhard, Rüger, Rüdiger, Fleckenstein, Bernhard, Stoerker, Jay, Calendar, R., Gold, L.   +9 more
core   +1 more source

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

Advanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li, Qizhe Zhang, Hanchen Chen, Kepeng Lin, Chengfang Luo, Mengying Yang, Wei Xu, Fan Yao, Jianbing Yan, Qing‐Yong Yang, Xuehai Hu   +10 more
wiley   +1 more source

Longitudinal change in blood DNA epigenetic signature after smoking cessation

Epigenetics, 2022
Cigarette smoking is associated with epigenetic changes that may be reversible following smoking cessation. Whole blood DNA methylation was evaluated in Framingham Heart Study Offspring (n = 169) and Third Generation (n = 30) cohort participants at two ...
Amena Keshawarz, Roby Joehanes, Weihua Guan, Tianxiao Huan, Dawn L. DeMeo, Megan L. Grove, Myriam Fornage, Daniel Levy, George O’Connor   +8 more
doaj   +1 more source

Sensitivity of intergenic regions of yeast mitochondrial DNA to single‐strand‐specific nucleases [PDF]

FEBS Letters, 1988
The reactivity of mitochondrial DNA (mtDNA) sequences from Torulopsis glabrata and Saccharomyces cerevisiae towards single‐strand‐specific nucleases has been examined. AT‐rich stretches located in intergenic sequences from both yeasts were cleaved by nucleases when the sequences were contained in supercoiled plasmid DNA. In particular ori/rep sequences
openaire   +2 more sources