Results 251 to 260 of about 614,734 (318)

Epigenetic research methods and animal models for intervertebral disc degeneration (Review). [PDF]

Mol Med Rep
Cui X, Zeng L, Zhang W, Xi L, Wang R, Jia D, Safa, Feng H, Jia H.   +8 more
europepmc   +1 more source

Light‐Activatable Nitric Oxide Release via Intramolecular Electron Transfer for Tumor Pyroptosis Induction

Advanced Science, EarlyView.
This work proposes a novel strategy to fabricate unimolecular pyroptosis photoinitiators activated by deep‐red light at low light doses. It relies on a photosensitization mechanism to trigger nitric oxide (NO) release from benzisothiadiazole‐based N‐nitrosanilines without modification of nitro moieties, thereby boosting pyroptosis‐mediated ...
Chuangxin Zhang, Ruipeng Li, Yunxia Wang, Feng Liu, Liheng Feng   +4 more
wiley   +1 more source

Mitochondrial Metabolic Reprogramming in Colorectal Cancer-Associated Fibroblasts: An Up-to-Date Review. [PDF]

Cancers (Basel)
Li Y, Chanda D, Jeon SW, Jeon JH, Kim MJ.   +4 more
europepmc   +1 more source

Metabolic Imbalance Triggers Adaptive Remodeling to Accelerate Diploidization in Murine Haploid Embryonic Stem Cells

Advanced Science, EarlyView.
In this article, Shuai and colleagues demonstrate that metabolic remodeling drives self‐diploidization in murine haploid ESCs (haESCs). Mitochondrial dysfunction and imbalanced pyruvate metabolism underlie this process. Genome‐wide screening using haESCs identifies key mitochondrial quality‐control related genes, enabling a metabolism‐based medium that
Yi Fu, Wenhao Zhang, Yifan Zhang, Yu He, Yi Du, Yiding Zhao, Chunmeng Yao, Shengyi Sun, Xiaoyan Sheng, Qian Gao, Chao Tong, Ling Shuai   +11 more
wiley   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

Advanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang, Kejia Li, Ning Wang, Zhen Li, Zhiyong Zhang, Rocky S. Tuan, Yangzi Jiang   +6 more
wiley   +1 more source

Regenerative Approaches to Enhance the Skin Microenvironment and Boost Aesthetic Efficacy: A Narrative Review. [PDF]

Int J Mol Sci
Col VD, Ribas FF, Araldi RP.
europepmc   +1 more source

The complete mitochondrial genome sequence of the saprotrophic filamentous fungus <i>Umbelopsis nana</i>. [PDF]

Mitochondrial DNA B Resour
Iizuka R, Suzuki T, Katayama Y, Yoshida M.   +3 more
europepmc   +1 more source

The complete mitochondrial genome of <i>Boulenophrys sanmingensis</i> (Anura: Megophryidae). [PDF]

Mitochondrial DNA B Resour
Zheng ZY, Guo XH, Ding GH, Chen J.
europepmc   +1 more source

Genome of Facultatively Parthenogenetic Harvester (Opiliones) Indicates Frequent Mitonuclear Sequence Transfer and Novel Full-Length Insertions. [PDF]

Genome Biol Evol
Stellwagen SD, Burns M.
europepmc   +1 more source