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ZONAB Regulates DNA Methylation, Mitochondrial Function, and Entry into Cell Senescence of Endothelial Cells. [PDF]

Cells
Jiang W, Lynam E, Delafosse J, Birdsey GM, Randi AM, Matter K, Balda MS.   +6 more
europepmc   +1 more source

Mitochondria and the epigenome: maternal co-inheritance and crosstalk from oocyte to embryo. [PDF]

Cell Commun Signal
Lee SH, Cui XS.
europepmc   +1 more source

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Mitochondrial DNA and aging

Clinical Science, 2004
Among the numerous theories that explain the process of aging, the mitochondrial theory of aging has received the most attention. This theory states that electrons leaking from the ETC (electron transfer chain) reduce molecular oxygen to form O2•− (superoxide anion radicals).
Mikhail F, Alexeyev, Susan P, Ledoux, Glenn L, Wilson   +2 more
openaire   +2 more sources

Transcription of Mitochondrial DNA

Critical Reviews in Biochemistry, 1983
While mitochondrial DNA (mtDNA) is the simplest DNA in nature, coding for rRNAs and tRNAs, results of DNA sequence, and transcript analysis have demonstrated that both the synthesis and processing of mitochondrial RNAs involve remarkably intricate events.
H. F. Tabak, L. A. Grivell, P. Borst, Giuseppe Attardi   +3 more
openaire   +2 more sources

Mitochondrial DNA in Tumors

Toxicology Mechanisms and Methods, 2004
Mitochondria, cellular powerhouses, play a central role in apoptosis. In addition, they are suspected to contribute to aging. There is also increasing evidence that abnormalities in mitochondrial function help cancer development. Changes in mitochondrial transcription and oxidative phosphorylation pathways are observed in many types of cancer.
Anna, Lorenc, Jaroslaw, Bryk, Ewa, Bartnik   +2 more
openaire   +2 more sources