Results 31 to 40 of about 3,314,237 (327)

Extensive Structural Variations Between Mitochondrial Genomes of CMS and Normal Peppers (Capsicum Annuum L.) Revealed by Complete Nucleotide Sequencing [PDF]

open access: yes, 2014
Cytoplasmic male sterility (CMS) is an inability to produce functional pollen that is caused by mutation of the mitochondrial genome. Comparative analyses of mitochondrial genomes of lines with and without CMS in several species have revealed structural ...
Choi, Yoomi   +4 more
core   +2 more sources

A rapid and efficient method for enriching mitochondrial DNA from plants

open access: yesMitochondrial DNA. Part B. Resources, 2018
Current mitochondrial purification techniques are tedious and protracted due to their emphasis on recovering physiologically active mitochondria. However, for studies that are exclusively interested in isolating mitochondrial DNA (mtDNA) for applications
Mackenzie M. Strehle   +2 more
doaj   +1 more source

The Role of Mitochondria in Human Fertility and Early Embryo Development: What Can We Learn for Clinical Application of Assessing and Improving Mitochondrial DNA?

open access: yesCells, 2022
Mitochondria are well known as ‘the powerhouses of the cell’. Indeed, their major role is cellular energy production driven by both mitochondrial and nuclear DNA.
Amira Podolak   +2 more
doaj   +1 more source

Mitochondrial DNA-related Disorders

open access: yesBioscience Reports, 2007
Mitochondrial diseases are a group of disorders due to a mitochondrial respiratory chain deficiency. They may depend on mitochondrial genome (mtDNA-related disorders) as well as on a nuclear genome defect (nDNA-related disorders). mtDNA-related disorders encompass an increasing number of clinical pictures associated with more than 250 different ...
MANCUSO, MICHELANGELO   +6 more
openaire   +4 more sources

Ergosterol reduction impairs mitochondrial DNA maintenance in S. cerevisiae [PDF]

open access: yes, 2019
Sterols are essential lipids, involved in many biological processes. In Saccharomyces cerevisiae, the enzymes of the ergosterol biosynthetic pathway (Erg proteins) are localized in different cellular compartments.
Balliano, Gianni   +6 more
core   +2 more sources

MitoNeoD:a mitochondria-targeted superoxide probe [PDF]

open access: yes, 2017
Mitochondrial superoxide (O2⋅−) underlies much oxidative damage and redox signaling. Fluorescent probes can detect O2⋅−, but are of limited applicability in vivo, while in cells their usefulness is constrained by side reactions and DNA intercalation.
Anderson, Robert F.   +19 more
core   +5 more sources

Mitochondrial heat shock protein 70, a molecular chaperone for proteins encoded by mitochondrial DNA [PDF]

open access: yes, 1994
Mitochondrial heat shock protein 70 (mt-Hsp70) has been shown to play an important role in facilitating import into, as well as folding and assembly of nuclear-encoded proteins in the mitochondrial matrix.
Craig, Elisabeth A.   +3 more
core   +4 more sources

Determination of Mitochondrial DNA Upon Drug Treatment

open access: yesBio-Protocol, 2015
Drug-induced mitochondrial injury can be caused by many different mechanisms including inhibition of mitochondrial DNA replication, transcription, translation, and altered protein function.
Michel Perron, Joy Feng
doaj   +1 more source

Clinical features of the late ⁃ onset mitochondrial encephalomyopathy with lactic acidosis and stroke⁃like episodes

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2020
Objective To summarize the clinical, pathological and genetic features of 10 patients with late ⁃ onset mitochondrial encephalomyopathy with lactic acidosis and stroke ⁃ like episodes (MELAS).
Dan⁃hua ZHAO   +7 more
doaj  

A Monomer-to-Trimer Transition of the Human Mitochondrial Transcription Termination Factor (mTERF) Is Associated with a Loss of in Vitro Activity [PDF]

open access: yes, 2004
The human mitochondrial transcription termination factor (mTERF) is a nuclear-encoded 39-kDa protein that recognizes a mtDNA segment within the mitochondrial tRNALeu(UUR) gene immediately adjacent to and downstream of the 16 S rRNA gene. Binding of mTERF
Asin-Cayuela, Jordi   +2 more
core   +1 more source

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