Results 171 to 180 of about 2,773,935 (245)

Analysis of the physical state of different human papillomavirus DNAs in intraepithelial and invasive cervical neoplasm

Journal of Virology, 1991
A. Cullen, R. Reid, M. Campion, A. Lorincz   +3 more
semanticscholar   +1 more source

Lactoferrin treatment activates acetylcholinesterase, decreasing acetylcholine levels in non‐small cell lung cancer (NSCLC) cell culture supernatants, inhibiting cell survival

FEBS Open Bio, EarlyView.
Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel, Caroline Wozniak, Aya Sabri, Ben Haddad, Brooke Lopo, Alvaro Cobos, Sarah Sarofim, Jeffrey Guthrie, Deborah Heyl, Hedeel Guy Evans   +9 more
wiley   +1 more source

Portraits of clonal hematopoiesis in DNMT3A/TET2/ASXL1-mutant myelodysplastic neoplasms and acute myeloid leukemia. [PDF]

Ann Hematol
Patel SA, Khedr S, Hutchinson L, Xie Y, Khouri MR, Cerny J, Gerber JM.   +6 more
europepmc   +1 more source

Overexpression of CDT1 inhibits cell cycle progression at S phase by interacting with the mini‐chromosome maintenance complex and causes DNA damage

FEBS Open Bio, EarlyView.
CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama, Nonoka Takayama, Rina Tanaka, Yuuki Arai, Yohko Yamaguchi, Yuko Nawata, Yutaro Azuma, Shusuke Tada   +7 more
wiley   +1 more source

Integrating TBSRTC subcategorization and <i>BRAF</i> V600E testing for precision management of Bethesda III thyroid nodules: a WHO 5th edition-based study highlighting subtype-specific diagnostic disparities. [PDF]

Front Oncol
Yu Q, Yang Z.
europepmc   +1 more source

Mitochondrial DNA and carcinogenesis (review).

Molecular Medicine Reports, 2012
L. Grzybowska-Szatkowska, B. Ślaska
semanticscholar   +1 more source

HSP70 governs permeability and mechanotransduction in primary human endothelial cells

FEBS Open Bio, EarlyView.
HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez, Everton G. Melo, Isadora C. B. Pavan, Percíllia V. S. Oliveira, Luiza B. C. T. Coimbra, Thaís L. S. Araujo   +5 more
wiley   +1 more source

Subsequent primary and secondary neoplasms in childhood cancer survivors. [PDF]

Pol J Radiol
Bekiesińska-Figatowska M, Bilska K, Szkudlińska-Pawlak S, Klepacka T, Raciborska A, Koch I, Michalak E.   +6 more
europepmc   +1 more source

Homologous expression and purification of human HAX‐1 for structural studies

FEBS Open Bio, EarlyView.
This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley   +1 more source

Distal noncontiguous recurrence and sarcomatous transformation of glioblastoma with stable molecular profile: illustrative case. [PDF]

J Neurosurg Case Lessons
Howran J, Andrews K, Ogawa K, Cook D, Purzner J, Ynoe Moraes F, Rossiter JP, Purzner T.   +7 more
europepmc   +1 more source