Results 151 to 160 of about 2,091,584 (306)

Cutaneous CD4+/ CD56 hematodermic neoplasm

, 2011
CD4+/CD56+ hematodermic neoplasm, formerly known as blastic NK cell lymphoma, is a rare and aggressive neoplasm with a high incidence of cutaneous involvement, risk of leukemic dissemination and poor prognosis.
Kavala, Mukaddes, Buyukbabani, Nesimi, Kocaturk, Emek, Zindanci, Ilkin, Koc, Melek   +4 more
core  

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

FEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo, Sandy Richter, Christoph Bach, Wieland Kiess, Anna Kirstein, Diana Le Duc, Antje Garten   +6 more
wiley   +1 more source

[Analysis of DNA adducts in molecular epidemiology of human neoplasms].

Postepy higieny i medycyny doswiadczalnej, 1994
The techniques applicable for DNA adducts identification and quantitation are critically reviewed. The review also presents the data concerning an analysis of DNA adducts resulted from occupational exposure, tobacco smoking, diet and chemotherapy of tumors.
K, Szyfter, W, Baer-Dubowska, D, Brauze
openaire   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Mediating Effect of White Blood Cells and Tobacco Exposure on Cervical Neoplasm Risk Among Taiwanese Women

[[abstract]]Background: Both the high-risk human papillomavirus (HR-HPV) infection and tobacco exposure are significantly associated with cervical neoplasm risk. Immune cells play important roles in carcinogenesis.
Wang, Wei-Jun, Chang, Ching Wen, Shih, Ya Wen, Fang, Hui Fen, Tsai, Jia Ruey, Lin, Chia Ling, Chang, Hui-Chen Rita, Rias, Yohanes Andy, Tsai, Hsiu Ting   +8 more
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

A Novel <i>PICALM::AFF3</i> Fusion t(2;11) (q11.2;q21) in a Case of Myelodysplastic Neoplasm, Post Cytotoxic Therapy. [PDF]

EJHaem
Don MD, Chousal JN, Song W, Murray SS, Wong RL, Hamdan A, Wang HY.   +6 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

Identification and characterization of a novel distinct Pineal Neoplasm with Neuroendocrine and Epithelial Differentiation (PINNED). [PDF]

Acta Neuropathol
Bode H, Suwala AK, Gudenas B, Fürst A, Geisemeyer N, Altendorf L, Hack K, Giannini C, Abdullaev Z, Brandner S, Beckervordersandforth J, Snuderl M, Radke J, Rodríguez-Antolín C, Villa C, Godfraind C, Lowder L, Mammoser A, Kenning TJ, Hertel K, Brodhun M, Gerlach R, Mawrin C, Karelis G, Kerbs P, Bludau I, von Deimling A, Pfister SM, Sahm F, Vasiljevic A, Thomas C, Hasselblatt M, Northcott P, Kool M, Schüller U.   +34 more
europepmc   +1 more source