Results 171 to 180 of about 2,091,584 (306)

ATM mutations in myelodysplastic neoplasms, acute myeloid leukemia, and myeloproliferative neoplasms: a systematic review. [PDF]

Med Oncol
Laurindo LO, Parente MLB, Sasahara GL, Goes JVC, Sampaio LR, Pinheiro YV, Pinheiro RF.   +6 more
europepmc   +1 more source

DNA Flow Cytometry in the Assessment of Solid Neoplasms

Annals of Saudi Medicine, 1992
openaire   +2 more sources

Threonine 348 regulates the subcellular localization of PTEN

FEBS Open Bio, EarlyView.
Thr348 in the C2 domain is a key contributor to PTEN subcellular localization. The PTEN350 fragment and PTENA4 accumulated in the nucleus, whereas PTENK13R,A4 predominantly localized to the plasma membrane. In contrast, substitution of Thr348 with Asp (T348D) disrupted these characteristic localization patterns, resulting in predominant cytoplasmic ...
Takashi Kato, Suzu Tanaka, Miyu Ohashi
wiley   +1 more source

Spindle Cell Tumors with a <i>GAB1::ABL1</i> Fusion-Another Member of Protein-Kinase-Related Soft Tissue Neoplasms: An (Epi)Genetic Study of Six Cases with Benign Behavior. [PDF]

Int J Mol Sci
Hiemcke-Jiwa LS, Múdry P, Rullo E, Koopman B, Cleven AHG, van Gorp JM, van Noesel MM, Schoot RA, Polášková K, Ooft ML, Veccia N, Alaggio R, Barresi S, Patrizi S, Miele E, van Helvert S, Kester LA, Flucke U.   +17 more
europepmc   +1 more source

Development of DNA vaccines against B-cell neoplasms [PDF]

, 2001
For the development of DNA vaccines for B-cell malignancies, three aspects were studied. First, tumour Ig genes of B-cell malignancies were analysed to gain insight into the nature of the tumour antigen and the cell of origin in B-cell tumours. Transcripts of VHDJH-constant region (VH-C) sequences of the rare B-cell malignancy hairy cell leukemia (HLC)
openaire  

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

Repair of DNA double-strand breaks after low radiation doses in childhood cancer survivors and matched cancer-free individuals. [PDF]

Proc Natl Acad Sci U S A
Mirsch J, Cordoni RN, Schmitt C, Dehnert MI, Schulze A, Galetzka D, Zahnreich S, Scholz-Kreisel P, Hankeln T, Marron M, Blettner M, Ronckers CM, Schmidberger H, Löbrich M.   +13 more
europepmc   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

Clonal Hematopoiesis Across the Cancer Treatment Continuum: A Scoping Review of Clonal Selection, Evolution, and Clinical Outcomes. [PDF]

Cancers (Basel)
AlShahrani AM.
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source