Results 181 to 190 of about 2,773,935 (245)

NUP98‐HOXA9‐transgenic zebrafish develop a myeloproliferative neoplasm and provide new insight into mechanisms of myeloid leukaemogenesis

British Journal of Haematology, 2011
A. M. Forrester, C. Grabher, Eileen R. McBride, Ellen R. Boyd, Märta H. Vigerstad, Alexander Edgar, F. Kai, Sahar I. Da'as, Elspeth M. Payne, A. Look, J. Berman   +10 more
semanticscholar   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

Impact of MGMT methylation on overall survival in solid tumors: A systematic review and meta-analysis. [PDF]

Exp Ther Med
Alzibdeh A, Khanfar A, Al-Hussaini M, Abuhijlih R, Mohamad I, Abdel-Razeq H, Abuhijla F.   +6 more
europepmc   +1 more source

Dietary nitrate and nitrite protect against doxorubicin‐induced cardiac fibrosis and oxidative protein damage in tumor‐bearing mice

FEBS Open Bio, EarlyView.
Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani, Xiaofei Chen, Nildris Cruz‐Diaz, Xuewei Zhu, Swati Basu, Daniel B. Kim‐Shapiro, David R. Soto‐Pantoja, Leslie B. Poole   +7 more
wiley   +1 more source

Pan-cancer atlas analysis of FANCB and its potential mechanism in cholangiocarcinoma. [PDF]

Discov Oncol
Fan Y, Li J, Wang H, Yao L, Wang X.
europepmc   +1 more source

Xenogeneic murine tyrosinase DNA vaccine for malignant melanoma of the digit of dogs.

Journal of Veterinary Internal Medicine, 2011
C. Manley, N. Leibman, J. Wolchok, I. Rivière, S. Bartido, D. Craft, P. Bergman   +6 more
semanticscholar   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

Integrating genotype-phenotype correlations into the diagnostic workflow of odontogenic tumors and cysts: insights from a 69 lesion cohort. [PDF]

Clin Oral Investig
Gültekin SE, Toközlü B, Heydt C, Büttner R.   +3 more
europepmc   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

ARHGAP11A, a member of Rho GTPase activating protein family, as a prognostic biomarker linked to DNA damage response across pan-cancer. [PDF]

BMC Cancer
Tan K, Wu Y, Zhang J, Ding Y, Cheng C, Yan Z, Wang X, Zhang L.   +7 more
europepmc   +1 more source