Results 91 to 100 of about 31,432 (120)

Regulatory structures of gene expression, DNA replication and DNA rearrangement in macronuclear genes of Stylonychia lemnae, a hypotrichous ciliate [PDF]

open access: yes, 1989
Ammermann   +53 more
core   +1 more source

How to survive and thrive without mitochondrial DNA: A protozoan's guide to ATP synthase modification

open access: yesBiochimica et Biophysica Acta (BBA) - Bioenergetics, 2010
Matthew K. Gould   +2 more
openaire   +2 more sources

DNA topoisomerases in the unicellular protozoan parasites: Unwinding the mystery

Biochemical Pharmacology, 2022
DNA topoisomerases are a group of enzymes present ubiquitously in all organisms from unicellular protozoan parasites to humans. These enzymes control the topological problems caused by DNA double helix in the cell during nucleic acid metabolism.
Swati, Lamba, Amit, Roy
openaire   +2 more sources

DNA Polymerases in Parasitic Protozoans Differ from Host Enzymes [PDF]

open access: possibleScience, 1980
Analysis of extracts of the bloodstream forms of Trypanosoma brucei showed that both DNA polymerase-α and DNA polymerase-β activities were present. The detection of DNA polymerase-β in T. brucei demonstrates the presence of this enzyme in unicellular organisms.
Anthony Cerami   +3 more
openaire   +2 more sources

Demystifying the potential of inhibitors targeting DNA topoisomerases in unicellular protozoan parasites

Drug Discovery Today, 2023
DNA topoisomerases are a group of enzymes omnipresent in all organisms. They maintain the DNA topology during replication, repair, recombination, and transcription. However, the structure of topoisomerase in protozoan parasites differs significantly from that of human topoisomerases; thus, this enzyme acts as a crucial target in drug development ...
Swati, Lamba, Amit, Roy
openaire   +2 more sources

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