Results 71 to 80 of about 76,669 (236)

Kinetoplast DNA‐aggregating proteins from the parasitic protozoan Crithidia fasciculata

FEBS Letters, 1990
Proteins from C. fasciculata, which preferentially aggregate the parasite's AT‐rich mitochondrial (kinetoplast) DNA in vitro, are reported. The aggregation is non‐topological, non‐covalent, independent of Mg2+ and ATP, but much improved by spennidine. We discuss how these proteins might modulate the shape and size of the parasite's mitochondrial genome.
openaire   +1 more source

DNA Topoisomerase as Drug Target in unicellular protozoan parasite Leishmania donovani

INDIAN JOURNAL OF PHYSIOLOGY AND ALLIED SCIENCES, 2022
Visceral leishmaniasis or Kala-Azar is a neglected tropical disease caused by the unicellular kinetoplastid parasite Leishmania donovani.The treatments available have various shortcomings like toxicity and high cost. The development of resistance in the strains makes thetreatment less effective. Hence, there is a need for new and better treatments. DNA
openaire   +1 more source

Response of Fecal Bacteria and Fungi to Tannin‐Rich Diets in Sika Deer (Cervus nippon): Evidence from Both Feeding Experiments and Field Investigations

Integrative Zoology, EarlyView.
Feeding with tannin‐rich diets altered the fecal microbial composition and increased the relative abundance of tannin‐degrading microbes. We hypothesize that fecal bacteria and fungi may play important roles in helping herbivores adapt to tannin‐rich diets but respond to different tannin concentrations varies.
Di Zhu, Feng Wu, Peiying Wen, Haiyang Gao, Xiaoran Hao, Hongfang Wang   +5 more
wiley   +1 more source

A chromosome-scale genome assembly of Giardia duodenalis by long-read sequencing of ten trophozoites

Scientific Data
Giardia duodenalis, a protozoan parasite of important zoonotic concern, is estimated to cause approximately 280 million human infections annually worldwide. Currently, genome sequencing of G.
Jingjing Sun, Yuancai Chen, Yizhuo Wei, Kaihui Zhang, Yin Fu, Zi Yan, Xingyu Zhu, Sumei Zhang, Longxian Zhang, Junqiang Li   +9 more
doaj   +1 more source

Cryptosporidium infection in patients with gastroenteritis in Sari, Iran [PDF]

, 2014
Background: Cryptosporidiosis is a common coccidian parasite infection in patients with diarrhea that has worldwide distribution especially in developed countries.
Ahmadpour, E., Gholami, S., Khanmohammadi, M., Nakhjiri, S.K., Paqhe, E.S., Ramazannipour, H., Shahbazi, A.   +6 more
core  

Domination Versus Sisterhoods in the Blood Microbiota of Migrating Birds: Patterns of Within‐ and Between‐Individual Blood Parasite Diversity Revealed Through Metabarcoding

Integrative Zoology, EarlyView.
Avian haemosporidian blood parasites are typically identified through Sanger sequencing of a partial cytochrome b fragment, the MalAvi barcoding region. Next‐generation sequencing is seldom used for avian blood parasite identification; this study demonstrates a higher detection rate of co‐infections via metabarcoding and its possible implications ...
Peter Pibaque, Gaia Porporato, Simone Cescutti, Alanis Cruz‐Flores, Tobias Busche, Anika Winker, Tim Maximilian Rapp, Patrick Bergkamp, Anna Doneva, Nayden Chakarov   +9 more
wiley   +1 more source

Formation of linear amplicons with inverted duplications in Leishmania requires the MRE11 nuclease. [PDF]

PLoS Genetics, 2014
Extrachromosomal DNA amplification is frequent in the protozoan parasite Leishmania selected for drug resistance. The extrachromosomal amplified DNA is either circular or linear, and is formed at the level of direct or inverted homologous repeated ...
Marie-Claude N Laffitte, Marie-Michelle Genois, Angana Mukherjee, Danielle Légaré, Jean-Yves Masson, Marc Ouellette   +5 more
doaj   +1 more source

Molecular confirmation of Sarcocystis fayeri in a donkey [PDF]

, 2017
Sarcocystis fayeri is a canine protozoan parasite with an equine intermediate host. Historically classified as an incidental pathogen, recent literature has described the toxic effects of Sarcocystis fayeri in human food poisoning, and highlighted ...
Coultous, Robert M., Raftery, Alexandra G., Shiels, Brian R., Sutton, David G.M., Weir, William   +4 more
core   +1 more source

Cytosolic delivery of bacterial metabolites by riboflavin transporters promotes MR1 antigen presentation and MAIT cell recognition

Immunology &Cell Biology, EarlyView.
VitBAg antigen presentation is promoted through a cytosolic pathway that reaches ligand‐receptive MR1 to present to MAIT cells, like the riboflavin transport pathway. Riboflavin solute carrier transporters can promote this MR1 presentation, but they are not essential for this role, suggesting redundant pathways to uptake VitBAg.
Sebastian Cruz‐Gomez, Hui Jing Lim, Brunda Nijagal, Yuting Yang, Nicole Lau, Jeffrey YW Mak, David P Fairlie, Hayley Newton, Mariolina Salio, Jose A Villadangos, Hamish EG McWilliam   +10 more
wiley   +1 more source

Leishmania tarentolae: taxonomic classification and its application as a promising biotechnological expression host

, 2019
In this review, we summarize the current knowledge concerning the eukaryotic protozoan parasite Leishmania tarentolae, with a main focus on its potential for biotechnological applications.
Klatt, S., Konthur, Z., Maslov, D., Simpson, L.   +3 more
core   +1 more source