Results 61 to 70 of about 47,206 (236)

Highly syntenic and yet divergent: a tale of two Theilerias [PDF]

, 2009
The published genomic sequences of the two major host-transforming Theileria species of cattle represent a rich resource of information that has allowed novel bioinformatic and experimental studies into these important apicomplexan parasites. Since their
Skilton, R., Villiers, Etienne P. de, Weir, W., de Villiers, E.P., Sunter, J., Bishop, Richard P., Bishop, R., Skilton, Robert A., Tait, A., Shiels, B., Langsley, G., Chaussepied, M.   +11 more
core   +1 more source

A compendium of extracellular vesicle biogenesis inhibitors: From bench to bedside

Interdisciplinary Medicine, EarlyView.
This review explores a decade of research on extracellular vesicles (EVs), detailing their biogenesis and roles in health and disease. It emphasizes EVs' relevance for potential medical applications covering various conditions such as cancer, neurodegeneration, inflammation, and infectious diseases, bridging experimental findings with clinical ...
Stefano Vecchione, Ana Talamillo, Juan M. Falcón‐Pérez   +2 more
wiley   +1 more source

Calpain Proteases and the Evolving Signaling Network in Insect Embryonic Patterning

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, EarlyView.
Insect embryonic Dorsal‐Ventral (DV) patterning relies on the BMP and Toll pathways to different extents. Calcium‐dependent cystein proteases of the Calpain family also exert an important function to pattern the DV axis. In Drosophila, Calpain A cleaves the Cactus/IkappaB inhibitor and modifies Toll signals in ventral regions of the embryo. In Rhodnius
Alison Julio, Helena Araujo
wiley   +1 more source

The genomes of three stocks comprising the most widely utilized live sporozoite Theileria parva vaccine exhibit very different degrees and patterns of sequence divergence [PDF]

, 2015
There are no commercially available vaccines against human protozoan parasitic diseases, despite the success of vaccination-induced long-term protection against infectious diseases.
Sonal Henson, Kyle Tretina, Thomas Njoroge, Tretina, Kyle, David Odongo, Silva, Joana C., Norling, Martin, Njoroge, Thomas, Roger Pelle, Bongcam-Rudloff, Erik, Henson, Sonal, Drábek, Elliott F, Elliott F. Drábek, Stephen Mwaura, Bishop, Richard P., Daubenberger, Claudia A., Richard P. Bishop, Pelle, Roger, Erik Bongcam-Rudloff, Martin Norling, Joana C. Silva, Odongo, David, Bishop, Richard P, Claudia A. Daubenberger, Drábek, Elliott F., Mwaura, Stephen, Qi, Weihong, Daubenberger, Claudia A, Silva, Joana C, Weihong Qi   +29 more
core   +1 more source

Characterization and functionality of two members of the SPFH protein superfamily, prohibitin 1 and 2 in Leishmania major

Parasites & Vectors, 2018
Background Leishmaniasis, a disease caused by parasites of the genus Leishmania, infects roughly 12 million people worldwide, with about two million new cases per year. Prohibitins (PHBs) are highly conserved proteins belonging to the stomatin-prohibitin
Teresa Cruz-Bustos, Ana Karina Ibarrola-Vannucci, Isabel Díaz-Lozano, José Luis Ramírez, A. Osuna   +4 more
doaj   +1 more source

Microbial communities and functional diversity in seafood

JSFA reports, EarlyView.
Abstract Functional diversity encompasses ecosystem processes that enhance adaptability to environmental change. This study explores the diversity of microorganisms associated with seafood. In this paper, we present our knowledge of microbial diversity in relation to seafood.
Christian Larbi Ayisi, Samuel Ayeh Osei, Grace Afumwaa Boamah, Gertrude Dzifa Mensah   +3 more
wiley   +1 more source

Genes of mitochondrial origin in the genus Entamoeba [PDF]

, 2002
Entamoeba histolytica is the protozoan parasite that causes amoebic dysentery and amoebic liver abscesses in humans. For many years it was believed to be a primitive organism because it lacks many typical eukaryotic features including mitochondria ...
Bakatselou, Christina
core   +1 more source

The Sole DNA Ligase in Entamoeba histolytica Is a High-Fidelity DNA Ligase Involved in DNA Damage Repair

Frontiers in Cellular and Infection Microbiology, 2018
The protozoan parasite Entamoeba histolytica is exposed to reactive oxygen and nitric oxide species that have the potential to damage its genome. E. histolytica harbors enzymes involved in DNA repair pathways like Base and Nucleotide Excision Repair. The
Elisa Azuara-Liceaga, Abigail Betanzos, Abigail Betanzos, Cesar S. Cardona-Felix, Cesar S. Cardona-Felix, Elizabeth J. Castañeda-Ortiz, Helios Cárdenas, Rosa E. Cárdenas-Guerra, Guillermo Pastor-Palacios, Guillermina García-Rivera, David Hernández-Álvarez, Carlos H. Trasviña-Arenas, Corina Diaz-Quezada, Esther Orozco, Luis G. Brieba   +14 more
doaj   +1 more source

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

Medicinal Research Reviews, EarlyView.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

The role of protozoan grazers in harmful algal bloom dynamics : tools for community and grazing analyses [PDF]

, 2013
textHarmful algal blooms (HABs) are becoming more prevalent throughout the world’s aquatic systems. These blooms have been the subjects of numerous studies because they can cause human health issues and economic impact through fish kills, contaminated ...
Campbell, Jena Renee
core