Results 51 to 60 of about 1,636,948 (186)

Characterization and functionality of two members of the SPFH protein superfamily, prohibitin 1 and 2 in Leishmania major

open access: yesParasites & Vectors, 2018
Background Leishmaniasis, a disease caused by parasites of the genus Leishmania, infects roughly 12 million people worldwide, with about two million new cases per year. Prohibitins (PHBs) are highly conserved proteins belonging to the stomatin-prohibitin
Teresa Cruz-Bustos   +4 more
doaj   +1 more source

The role of protozoan grazers in harmful algal bloom dynamics : tools for community and grazing analyses [PDF]

open access: yes, 2013
textHarmful algal blooms (HABs) are becoming more prevalent throughout the world’s aquatic systems. These blooms have been the subjects of numerous studies because they can cause human health issues and economic impact through fish kills, contaminated ...
Campbell, Jena Renee
core  

Discovery of novel active diamidines as clinical candidates against "Trypanosoma evansi" infection [PDF]

open access: yes, 2007
The animal pathogenic protozoan, Trypanosoma evansi, leads to a wasting disease in equines, cattle and camels, commonly known as Surra. It is extensively distributed geographically with a wide range of mammalian hosts and causes great economical loss ...
Gillingwater, Kirsten
core   +1 more source

Transgenic selection and underlying mechanisms in apicomplexan parasites

open access: yesThe FEBS Journal, EarlyView.
Transgenic selection markers have driven genetic engineering in apicomplexans, enabling precise, iterative experiments. This review discusses mechanistic details of drug selection markers, strategies for marker recycling, and practical considerations for several clinically relevant parasites.
Swaroop Peddiraju   +2 more
wiley   +1 more source

A chromosome-scale genome assembly of Giardia duodenalis by long-read sequencing of ten trophozoites

open access: yesScientific Data
Giardia duodenalis, a protozoan parasite of important zoonotic concern, is estimated to cause approximately 280 million human infections annually worldwide. Currently, genome sequencing of G.
Jingjing Sun   +9 more
doaj   +1 more source

Molecular detection of trypanosomatids and apicomplexans in owl tissues from the coast of Santa Catarina, Brazil [PDF]

open access: yesArquivo Brasileiro de Medicina Veterinária e Zootecnia
Owls (Strigiformes) are widely distributed across terrestrial ecosystems and play a key role as top predators, potentially exposing them to diverse infectious agents.
D.D. Assenheimer   +9 more
doaj   +2 more sources

Detection of Leishmania infantum DNA in blood samples of horses (Equus caballus) and donkeys (Equus asinus) by PCR

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2021
Visceral leishmaniasis (VL) is a neglected tropical disease caused by the Leishmania infantum parasite. The protozoan is able to infect several domestic and wild mammals. Since the first report on Leishmania spp.
João Augusto Franco Leonel   +9 more
doaj   +1 more source

Rescue of pATOM36‐depleted T. brucei by human MTCH1/2 reveals common features of protein insertases

open access: yesThe FEBS Journal, EarlyView.
Human MTCH1 and MTCH2 (with an N‐terminal extension) functionally complement the loss of pATOM36 in T. brucei, indicating that these evolutionarily distant proteins recognize a common set of substrates and share fundamental principles of mitochondrial outer membrane protein insertion. Structural analyses reveal a common hydrophilic cavity, supporting a
Stephan Berger   +4 more
wiley   +1 more source

From productive coupling to catalytic commitment: An evolutionarily tuned interdomain connector in Leishmania Aha1 orchestrates Hsp90 activation

open access: yesThe FEBS Journal, EarlyView.
LbAha1 activates LbHsp90 through a multistep mechanism in which productive N‐domain docking precedes ATP‐driven rearrangement and linker ordering. The LbAha1 linker transitions from a flexible to helical state, stabilizing an asymmetric, catalytically competent closed complex.
Paulo Roberto Dores‐Silva   +9 more
wiley   +1 more source

A rapid and simple method of detection of Blepharisma japonicum using PCR and immobilisation on FTA paper

open access: yesBMC Ecology, 2003
Background The rapid expansion in the availability of genome and DNA sequence information has opened up new possibilities for the development of methods for detecting free-living protozoa in environmental samples.
Hughes Jacqueline M   +2 more
doaj   +1 more source

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