Results 51 to 60 of about 47,206 (236)

Research Advances in Purine Phosphoribosyltransferases of Protozoan Parasites

open access: yesGuangdong nongye kexue, 2023
Parasitic protozoa are single-celled organisms that have adapted to live in cells of humans and animals. The protozoan parasites include Leishmania spp., Trypanosoma spp., Plasmodium spp., Toxoplasma gondii, Cryptosporidium spp., and Eimeria spp., which ...
Zhihui YU   +7 more
doaj   +1 more source

First record of gregarines (Apicomplexa) in seminal vesicle of insect

open access: yesScientific Reports, 2017
Gregarines (Apicomplexa) are a diverse group of protozoan parasites, which infects gut and other body cavities of invertebrate hosts. In reproductive system of insects, gregarine has been reported only in the accessory glands and spermathecae of females;
Glenda Dias   +6 more
doaj   +1 more source

Three different mutations in the DNA topoisomerase 1B in Leishmania infantum contribute to resistance to antitumor drug topotecan

open access: yesParasites & Vectors, 2021
Background The evolution of drug resistance is one of the biggest challenges in leishmaniasis and has prompted the need for new antileishmanial drugs.
Chloé Rosa-Teijeiro   +6 more
doaj   +1 more source

A Loop-Mediated Isothermal Amplification (LAMP) Assay Specific to Trichomonas tenax Is Suitable for Use at Point-of-Care

open access: yesMicroorganisms, 2022
Trichomonas tenax is a flagellated protozoan that inhabits the human and canine oral cavity in patients with poor oral hygiene and periodontal disease. The loop-mediated isothermal amplification (LAMP) assay could provide clinicians with a quick, cheap ...
Maurice A. Matthew   +3 more
doaj   +1 more source

Site-specific DNA double-strand breaks greatly increase stable transformation efficiency in Trypanosoma brucei. [PDF]

open access: yes, 2009
Genetic manipulation in African trypanosomes typically relies upon electroporation with chromosomal integration of DNA constructs by homologous recombination.
Glover, Lucy   +2 more
core   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

open access: yesBiotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva   +8 more
wiley   +1 more source

The modified base J is the target for a novelDNA-binding protein in kinetoplastid protozoans [PDF]

open access: yesThe EMBO Journal, 1999
DNA from Kinetoplastida contains the unusual modified base beta-D-glucosyl(hydroxymethyl)uracil, called J. Base J is found predominantly in repetitive DNA and correlates with epigenetic silencing of telomeric variant surface glycoprotein genes in Trypanosoma brucei. We have now identified a protein in nuclear extracts of bloodstream stage T.brucei that
Cross, Mike   +8 more
openaire   +2 more sources

Detection of Leishmania infantum DNA in blood samples of horses (Equus caballus) and donkeys (Equus asinus) by PCR

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2021
Visceral leishmaniasis (VL) is a neglected tropical disease caused by the Leishmania infantum parasite. The protozoan is able to infect several domestic and wild mammals. Since the first report on Leishmania spp.
João Augusto Franco Leonel   +9 more
doaj   +1 more source

Review of the fauna associated with wild and farmed mussels and oysters in the Mediterranean

open access: yesBiological Reviews, EarlyView.
ABSTRACT Mussels and oysters are important ecosystem engineers which modify the physical and chemical characteristics of the environment and create habitats that support highly diverse associated communities. In the Mediterranean Sea, the native Mediterranean mussel Mytilus galloprovincialis and the European flat oyster Ostrea edulis, together the ...
Barbara Mikac   +5 more
wiley   +1 more source

NMR structural analysis of DNA recognition by a novel Myb1 DNA-binding domain in the protozoan parasite Trichomonas vaginalis [PDF]

open access: yesNucleic Acids Research, 2009
The transcription regulator, tvMyb1, is the first Myb family protein identified in Trichomonas vaginalis. Using an electrophoretic mobility shift assay, we defined the amino-acid sequence from Lys(35) to Ser(141) (tvMyb1(35-141)) as the minimal DNA-binding domain, encompassing two Myb-like DNA-binding motifs (designated as R2 and R3 motifs) and an ...
Lou, Yuan-Chao   +6 more
openaire   +2 more sources

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