Results 91 to 100 of about 1,636,948 (186)

Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future

open access: yesMedicinal Research Reviews, Volume 46, Issue 6, Page 1574-1602, November 2026.
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley   +1 more source

Clozapine‐Associated Neutropenia With COVID‐19 Infection and the Role of Filgrastim

open access: yesProgress in Neurology and Psychiatry, Volume 30, Issue 4, November 2026.
ABSTRACT Clozapine is the gold standard, evidence‐based treatment of choice for treatment‐resistant schizophrenia. However, clozapine can induce serious, life‐threatening adverse effects, including neutropenia and agranulocytosis. There is accumulating evidence to suggest that rechallenging with clozapine should be considered in most patients with ...
Devender Singh Yadav
wiley   +1 more source

Modulation of protein synthesis relative to DNA synthesis alters the timing of differentiation in the protozoan parasite Theileria annulata.

open access: yes, 1997
The control of differentiation through time is critical for the correct ordering of sequential developmental events. A timing mechanism based on the number of mitotic divisions has been proposed for both higher eukaryote and protozoan parasite cellular ...
McKellar, Sue   +4 more
core   +3 more sources

Blood-sucking lice may disseminate Trypanosoma cruzi infection in baboons

open access: yesRevista do Instituto de Medicina Tropical de São Paulo, 2001
Trypanosoma cruzi (Schyzotrypanum, Chagas, 1909), and Chagas disease are endemic in captive-reared baboons at the Southwest Foundation for Biomedical Research, San Antonio, Texas.
Enrique R. ARGAÑARAZ   +7 more
doaj  

Disseminated ciliated protozoan infection in a Pacific dolphin (Tursiops gilli)

open access: yes, 2003
antibiotic agent; bacterial DNA; animal tissue; article; ciliate; dermatitis; DNA determination; dolphin; female; hepatitis; histopathology; lung parenchyma; lymphadenitis; Measles virus; nonhuman; pneumonia; polymerase chain reaction; protozoal ...
D Y Kim   +3 more
core  

CPs of protozoan parasites.

open access: yes, 2018
CPs of protozoan parasites.
Sharon L. Reed (606884)   +6 more
core   +1 more source

Marine biofilm bacteria evade eukaryotic predation by targeted chemical defense [PDF]

open access: yes, 2008
Many plants and animals are defended from predation or herbivory by inhibitory secondary metabolites, which in the marine environment are very common among sessile organisms.
Anahit Penesyan   +18 more
core   +1 more source

Decoding legacy phosphorus speciation in acidic, organic, and calcareous soils using solution‐state 31P nuclear magnetic resonance

open access: yesSoil Science Society of America Journal, Volume 90, Issue 6, November/December 2026.
Abstract Crops grown on over 40% of arable land are limited by low levels of bioavailable phosphorus (P). Additionally, about 80% of applied P becomes fixed in soil through sorption, precipitation, and complexation with humic–metal complex surfaces. This accumulated P, excluding geogenic P, is known as “legacy P” and can contribute to crop's needs if ...
MD Anik Mahmud   +10 more
wiley   +1 more source

Pathogen‐binding nanoparticles to inhibit host cell infection by heparan sulfate and sialic acid dependent viruses and protozoan parasites

open access: yesSmart Medicine
Global health faces an immense burden from infectious diseases caused by viruses and intracellular protozoan parasites such as the coronavirus disease (COVID‐19) and malaria, respectively.
Adrian Najer
doaj   +1 more source

DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes. [PDF]

open access: yes, 2013
Antigenic variation in African trypanosomes requires monoallelic transcription and switching of variant surface glycoprotein (VSG) genes. The transcribed VSG, always flanked by '70 bp'-repeats and telomeric-repeats, is either replaced through DNA double ...
Glover, Lucy   +12 more
core   +1 more source

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