Results 91 to 100 of about 1,636,948 (186)
Plasmepsins as Antimalarial Drug Targets—Then, Now, and the Future
ABSTRACT Malaria is a devastating disease caused by Plasmodium parasites. Plasmodium parasites express ten cathepsin D‐like aspartyl proteases, called plasmepsins (PMs). These PMs have diverse roles fulfill diverse functions throughout the parasite's lifecycle, though several exhibit functional redundancies. Among them, PMV, PMIV, and PMX are essential
Brad E. Sleebs
wiley +1 more source
Clozapine‐Associated Neutropenia With COVID‐19 Infection and the Role of Filgrastim
ABSTRACT Clozapine is the gold standard, evidence‐based treatment of choice for treatment‐resistant schizophrenia. However, clozapine can induce serious, life‐threatening adverse effects, including neutropenia and agranulocytosis. There is accumulating evidence to suggest that rechallenging with clozapine should be considered in most patients with ...
Devender Singh Yadav
wiley +1 more source
The control of differentiation through time is critical for the correct ordering of sequential developmental events. A timing mechanism based on the number of mitotic divisions has been proposed for both higher eukaryote and protozoan parasite cellular ...
McKellar, Sue +4 more
core +3 more sources
Blood-sucking lice may disseminate Trypanosoma cruzi infection in baboons
Trypanosoma cruzi (Schyzotrypanum, Chagas, 1909), and Chagas disease are endemic in captive-reared baboons at the Southwest Foundation for Biomedical Research, San Antonio, Texas.
Enrique R. ARGAÑARAZ +7 more
doaj
Disseminated ciliated protozoan infection in a Pacific dolphin (Tursiops gilli)
antibiotic agent; bacterial DNA; animal tissue; article; ciliate; dermatitis; DNA determination; dolphin; female; hepatitis; histopathology; lung parenchyma; lymphadenitis; Measles virus; nonhuman; pneumonia; polymerase chain reaction; protozoal ...
D Y Kim +3 more
core
Marine biofilm bacteria evade eukaryotic predation by targeted chemical defense [PDF]
Many plants and animals are defended from predation or herbivory by inhibitory secondary metabolites, which in the marine environment are very common among sessile organisms.
Anahit Penesyan +18 more
core +1 more source
Abstract Crops grown on over 40% of arable land are limited by low levels of bioavailable phosphorus (P). Additionally, about 80% of applied P becomes fixed in soil through sorption, precipitation, and complexation with humic–metal complex surfaces. This accumulated P, excluding geogenic P, is known as “legacy P” and can contribute to crop's needs if ...
MD Anik Mahmud +10 more
wiley +1 more source
Global health faces an immense burden from infectious diseases caused by viruses and intracellular protozoan parasites such as the coronavirus disease (COVID‐19) and malaria, respectively.
Adrian Najer
doaj +1 more source
DNA break site at fragile subtelomeres determines probability and mechanism of antigenic variation in African trypanosomes. [PDF]
Antigenic variation in African trypanosomes requires monoallelic transcription and switching of variant surface glycoprotein (VSG) genes. The transcribed VSG, always flanked by '70 bp'-repeats and telomeric-repeats, is either replaced through DNA double ...
Glover, Lucy +12 more
core +1 more source

