Results 221 to 230 of about 315,433 (266)
Some of the next articles are maybe not open access.
Structure and organization of ribosomal DNA
Biochimie, 1991Three trends are seen in the organization of ribosomal DNA genes during evolution: 1) gradual separation and separability of the regulation of transcription of 5S and larger subunit rRNAs; 2) retention of a transcription unit containing both large and small rRNAs; and 3) clustering of genes for both 5S and 18S-28S rDNAs, with the possible association ...
A K, Srivastava, D, Schlessinger
openaire +2 more sources
Ribosomal DNA as target for the assessment of DNA degradation of human and canine DNA
Legal Medicine, 2021The assessment of DNA amount and DNA integrity can support forensic DNA analysis, in particular of problematic traces such as single telogen hairs where STR typing success is often hampered by low amounts and strong degradation of nuclear DNA. Common strategies consist of quantitative polymerase chain reaction (qPCR)-based analysis of the abundance of ...
Sarah Aurora, Heß +5 more
openaire +2 more sources
Heterogeneity in cucumber ribosomal DNA
Theoretical and Applied Genetics, 1986Restriction and hybridization analysis of cucumber native ribosomal (r) DNA purified from actinomycin-D/CsCl gradients suggested that the repeat units were heterogeneous in both length and sequence. Several full length rDNA repeat units were cloned and five are described which account for all the EcoR I and Xba I fragments present in native DNA. One of
T A, Kavanagh, J N, Timmis
openaire +2 more sources
The Ribosomal DNA Plasmids of Entamoeba
Parasitology Today, 1998In most organisms, the nuclear ribosomal RNA (rRNA) genes are highly repetitive and arranged as tandem repeats on one or more chromosomes. In Entamoeba, however, these genes are located almost exclusively on extrachromosomal circular DNA molecules with no clear evidence so far of a chromosomal copy.
S, Bhattacharya, I, Som, A, Bhattacharya
openaire +2 more sources
Ribosomal DNA of Caenorhabditis elegans
Journal of Molecular Biology, 1981Abstract We have characterized the organization of the genes coding for 18 S, 5·8 S and 26 S ribosomal RNAs in the nematode Caenorhabditis elegans . These ribosomal genes, present in about 55 copies per haploid genome, alternate in a repeating tandem array.
J G, Files, D, Hirsh
openaire +2 more sources
Journal of Molecular Biology, 1980
Abstract We have analysed the ribosomal DNA of Calliphora erythrocephala, a Dipteran fly of the same sub-order as Drosophila melanogaster, through a series of rDNA † fragments cloned in a plasmid vector. We have mapped the sites for eight restriction enzymes within these plasmids, and positioned the regions coding for the 18 S and 28 S rRNAs within ...
K, Beckingham, R, White
openaire +2 more sources
Abstract We have analysed the ribosomal DNA of Calliphora erythrocephala, a Dipteran fly of the same sub-order as Drosophila melanogaster, through a series of rDNA † fragments cloned in a plasmid vector. We have mapped the sites for eight restriction enzymes within these plasmids, and positioned the regions coding for the 18 S and 28 S rRNAs within ...
K, Beckingham, R, White
openaire +2 more sources
Ribosomal DNA and Neurological Disorders
Current Molecular MedicineRibosomal DNA (rDNA) is important in the nucleolus and nuclear organization of human cells. Defective rDNA repeat maintenance has been reported to be closely associated with neurological disorders, such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, amyotrophic lateral sclerosis, frontotemporal dementia, depression, suicide, etc ...
Hong Zhou +6 more
openaire +2 more sources
Ribosomal DNA and the nucleolus at the heart of aging
Trends in Biochemical Sciences, 2022The rRNA genes [ribosomal DNA (rDNA)] are organized in a prominent nuclear compartment, the nucleolus. It is now well established that the nucleolus functions beyond ribosome biosynthesis, regulating several physiological cellular responses. The nucleoli constitute dynamic genomic/nuclear hubs and demonstrate unique inherent characteristics, rendering ...
Kasselimi, Eirini +3 more
openaire +2 more sources
Synthesis of ribosomal DNA in conjugating Tetrahymena
Experimental Cell Research, 1979Abstract In the ciliate protozoan Tetrahymena thermophila, a single integrated gene coding for ribosomal RNA in the micronucleus is amplified during the sexual cycle to yield many copies of extrachromosomal palindromic rDNA in the macronucleus. Hybridization of newly synthesized DNA with rRNA has shown that extensive rDNA synthesis takes place early ...
R E, Pearlman +3 more
openaire +2 more sources
Natural selection and ribosomal DNA in Drosophila
Genome, 1989Natural populations of Drosophila mercatorum are variable for the number of X-linked 28S ribosomal genes bearing a 5-kilobase insert. A separate polymorphic X-linked gene controls whether 28S repeats bearing the insert are preferentially underreplicated during the formation of polytene tissue.
A R, Templeton +3 more
openaire +2 more sources