Results 211 to 220 of about 315,433 (266)

CGAS (Chloroplast Genome Analysis Suite): An automated python pipeline for comprehensive comparative chloroplast genomics

iMetaOmics, EarlyView.
Chloroplast Genome Analysis Suite (CGAS) is a comprehensive bioinformatics pipeline that streamline chloroplast genome analysis from raw sequencing reads to publication‐ready outputs. The suite integrates 14 specialized modules organized across three sequential phases.
Abdullah, Rushan Yan, Xiaoxuan Tian
wiley   +1 more source

Medicinal Plants: A Promising Therapeutic Approach for Addressing Antimicrobial Resistance. [PDF]

Int J Mol Sci
Zhou H, Du J, Jia M, Li Y, Zheng K.
europepmc   +1 more source

Gene expression signatures from single‐cell transcriptomics predict Sjögren's syndrome

iMetaOmics, EarlyView.
A machine learning‐based 12‐gene signature (SjS.Sig) was developed from scRNA‐seq data of PBMCs from Sjögren's syndrome patients. The model was validated using bulk RNA‐seq datasets and further confirmed through flow cytometry and qPCR analysis in an independent clinical cohort, demonstrating robust diagnostic potential.
Shumin Cheng, Ling Yan, Yilin Wu, Yan Li, Ziheng Ye, Zhen Zhang, Yi Zhang, Jingyun Ma, Yuhong Liang, Zhaofan Luo, Huacheng Wang, Meili Gao, Chao Qin, Ke Zhu, Yun Leng, Kamran Ullah, Jun Liang, Haiyan Yan, Guan Yang, Yingqian Mo, Bihui Huang   +20 more
wiley   +1 more source

The SL-I structural element of the 3' UTR region of West Nile virus participates in the regulation of viral translation. [PDF]

J Gen Virol
Romero-López C, Bueno-Arribas P, Berzal-Herranz A.   +2 more
europepmc   +1 more source

Symbiotic Germination Technique of an Endangered Epiphytic Orchid Dendrobium sinominutiflorum: A Promising Conservation Application 濒危附生兰科植物勐海石斛 (Dendrobium sinominutiflorum) 的共生萌发技术:一种具有应用前景的保护策略

Integrative Conservation, EarlyView.
We developed an effective ex‐situ conservation approach for an endangered orchid species, Dendrobium sinominutiflorum. A compatible fungal strain Tulasnella sp. was obtained by using in‐situ seed baiting technique. The Symbiotic germination with Tulasnella sp. significantly promotes seed germination and seedling growth.
Han‐Xiao Huang, Lu Tang, Xiang‐Wan Yu, Yin‐Ling Luo, Peng Chen, Yun‐Hong Tan, Yan Luo   +6 more
wiley   +1 more source

Targeting eIF5A combats breast cancer progression by ClpP‐dependent mitochondrial oxidative stress

Interdisciplinary Medicine, EarlyView.
This study identified the eIF5A‐ClpP axis as a key driver of breast cancer progression. Targeting eIF5A suppresses tumor growth by inducing ClpP‐dependent mitochondrial oxidative stress, revealing a novel therapeutic vulnerability. Abstract Breast cancer (BC) poses a persistent global health challenge, necessitating new therapeutic targets.
Jinmei Zhu, Baoyuan Tang, Bei Xie, Haohua Deng, Haitang Yang, Lei Ma, Ziqing Zhang, Yicheng Ma, Xingyuan Ma, Shuaiyang Wang, Jing Li, Lei Zhao, Wengui Shi, Linjing Li   +13 more
wiley   +1 more source

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Circular ribosomal DNA and ribosomal DNA: replication in somatic amphibian cells

Chromosoma, 1975
Pulse labelled rDNA from cultured somatic cells of Xenopus laevis was examined by electron microscope autoradiography. The pattern of replication closely resembles that of bulk chromosomal DNA and differs considerably from rDNA synthesis during amplification in the oocyte.
J D, Rochaix, A P, Bird
openaire   +2 more sources

Non-canonical DNA structures in the human ribosomal DNA

Histochemistry and Cell Biology, 2023
Non-canonical structures (NCS) refer to the various forms of DNA that differ from the B-conformation described by Watson and Crick. It has been found that these structures are usual components of the genome, actively participating in its essential functions.
Evgeny, Smirnov, Pavla, Molínová, Nikola, Chmúrčiaková, Tomáš, Vacík, Dušan, Cmarko   +4 more
openaire   +2 more sources