Biokatalysatoren für die Geranylierung von Peptiden mit Linearen und Zyklischen Prenylgruppen
A combination of genome mining, synthetic biology, and biocatalytic assays revealed enzymes that install linear and cyclized prenyl moieties on ribosomally or chemically synthesized peptides. The promiscuity of both enzymes, while being specific for modification of C‐terminal tryptophans, enables enzymatic access to peptide terpenoid hybrids ...
Sarolt Magyari +10 more
wiley +1 more source
Full ribosomal operon sequencing of anaerobic gut fungi (phylum <i>Neocallimastigomycota</i>): insights on its markers and phylogenetic resolution. [PDF]
Young D +22 more
europepmc +1 more source
Mitochondrial Genome Reduction and Accelerated Evolution in Planktonic Foraminiferans. [PDF]
Lai HT, Lai MW, Wang TH, Ren H, Ku C.
europepmc +1 more source
Another host, another mystery: Infection of polychaete Pista palmata (Annelida: Terebellidae) with a new blood fluke (Digenea: Aporocotylidae) in the coastal Northwest Atlantic Ocean. [PDF]
Chowansky AN +3 more
europepmc +1 more source
Biocatalysts for Peptide Geranylation With Linear and Cyclic Prenyl Groups
A combination of genome mining, synthetic biology, and biocatalytic assays revealed enzymes that install linear and cyclized prenyl moieties on ribosomally or chemically synthesized peptides. The promiscuity of both enzymes, while being specific for modification of C‐terminal tryptophans, enables enzymatic access to peptide terpenoid hybrids.
Sarolt Magyari +10 more
wiley +1 more source
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu +8 more
wiley +1 more source
Primer-Less Species Identification Throughout Fungal (<i>Tuber magnatum</i>), Plant (<i>Corylus avellana</i>) and Animal (<i>Eisenia fetida</i>) Kingdoms by Direct RNA Sequencing. [PDF]
Malewski T +8 more
europepmc +1 more source
Antimicrobial resistance (AMR) is an escalating global threat driven by antimicrobial use in aquaculture and livestock. Resistant pathogens and genes can spread across humans, animals, and the environment through interconnected ecosystems. Using a One Health approach, this review emphasizes antimicrobial stewardship, regulatory strengthening, enhanced ...
Mir Mohammad Ali +10 more
wiley +1 more source

