Results 261 to 270 of about 578,618 (302)

Single‐stranded DNA‐containing bacteriophages

BioEssays, 1986
AbstractRoots presents articles on major discoveries that laid the basis for contemporary molecular and cellular biology. In this article, Norton D. Zinder reviews the first findings about the single‐stranded DNA‐containing bacteriophages and what is known today about the genetics and molecular biology of these phages.
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Chain persistency in single-stranded DNA

Physical Review E, 2004
We develop a theoretical approach to hairpin-loop formation of single-stranded (ss) DNA by treating the strand as a two-state system in which bases are either "stacked" or "unstacked." The looping kinetics of ssDNA is shown to be intrinsically different from that of a wormlike chain; it is mainly controlled by stacking-breakage probability, not by the ...
Anirban, Sain, Bae-Yeun, Ha, Heng-Kwong, Tsao, Jeff Z Y, Chen   +3 more
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Single-strand DNA triple-helix formation

Biochemistry, 1990
Chemical modification studies provide evidence that single-stranded oligodeoxyribonucleotides can form stable intrastrand triple helices. Two oligonucleotides of opposite polarity were synthesized, each composed of a homopurine-homopyrimidine hairpin stem linked to a pyrimidine sequence which is capable of folding back on the hairpin stem and forming ...
Häner, Robert, Dervan, Peter B.
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Nitrosourea-induced DNA single-strand breaks

Biochemical Pharmacology, 1979
Abstract Reaction of DNA with nitrosoureas in vitro results in extensive formation of alkali labile sites. Two types of single-strand scission (SSS) processes may be distinguished by their different rates: (1) type I SSS which occurs relatively fast at high pH, and (2) type II SSS which is a much slower process.
J W, Lown, L W, McLaughlin
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Quantitative Amplification of Single-Stranded DNA

2012
Single-stranded DNA (ssDNA) intermediates play an important role in processes such as DNA replication and homologous recombination, DNA damage responses, and DNA repair. Using quantitative amplification of ssDNA (QAOS), ssDNA arising during various cellular processes in complex genomes can be quantified at numerous single-copy and repetitive loci. QAOS
Eva-Maria, Holstein, David, Lydall
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Helical configuration of single-stranded DNA

Journal of Theoretical Biology, 1969
Abstract Luzzati, Mathis, Masson & Witz (1964) have recently discovered an intermediate form of DNA which may be a single-stranded DNA in helical form. Its linear mass density is one nucleotide per 3;-4 A and its radius of gyration, R s , is 68% of that of the double helix form, R d .
R L, Chen, P, Fong
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Electron microscopy of single-stranded DNA

Journal of Molecular Biology, 1970
A method is described for the quantitative study of single-stranded DNA by electron microscopy. It permits the determination of the size of single-stranded DNA with sample standard deviations between 5 and 8%. Since 80 to 100% of the molecules in a given field are usually measurable, size distributions can also be obtained. The linear density of single-
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Conformational changes of single-stranded DNA

Journal of Molecular Biology, 1969
Abstract The conformation of intact, essentially monodisperse, single-stranded T7 DNA was studied in solutions between 0.001 and 1 m -NaCl at neutral and alkaline pH and temperatures between 5 and 35 °C. Over-all shape is assessed by measurement of S 20,w 0 , and base stacking by absorbance at 260 mμ.
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Persistence Length of Single-Stranded DNA

Macromolecules, 1997
The self-diffusion coefficient of a series of DNA fragments ranging from 280 to 5386 bases has been measured by fluorescence recovery after photobleaching after thermal denaturation in 8 M urea. The total persistence length p of single-stranded DNAs and its variation in ionic strength down to 10-3 M has been deduced.
Tinland, Bernard, Pluen, Alain, Sturm, Jean, Weill, Gilbert   +3 more
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DNA single-strand breaks and neurodegeneration

DNA Repair, 2004
The association of human genetic disorders with defects in the DNA damage response is well established. Most of the major DNA repair pathways are represented by diseases in which that pathway is absent or impaired, including those responsible for repairing DNA double-strand breaks.
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