Results 111 to 120 of about 7,352 (214)
Spectrofluorometric measurement of the binding of ethidium to superhelical DNA from cell nuclei.
, 1978 Structures retaining many of the morphological features of nuclei may be released by lysing HeLa cells in solutions containing non-ionic detergents and high concentrations of salt. These nucleoids contain few chromatin proteins.
Cook, Peter, Brazell, IA, Cook, PR
core +1 more source
Specific binding of chartreusin, an antitumor antibiotic, to DNA
, 1983 Chartreusin, an antitumor and antibacterial antibiotic, was found to inhibit negatively superhelical DNA-relaxation catalyzed by prokaryotic topoisomerase I and conversion of the superhelical DNA into unit length linear form catalyzed by single-strand ...
Isono, Kiyoshi +11 more
core +1 more source
Characterization of purified DNA-relaxing enzyme from human tissue culture cells
, 1975 Superhelical simian virus 40 DNA migrates more rapidly during electrophoresis in agarose gels than covalently closed DNA free of superhelical turns (relaxed DNA). The difference in electrophoretic mobility between superhelical and relaxed DNA was used to
Keller, W., Keller, W.
core
Elucidating the DNA–Histone Interaction in Nucleosome from the DNA–Dendrimer Complex
, 2016 The electrostatic complex of DNA with poly(amidoamine) G6 dendrimer (called “dendriplex”) is used as a model system to resolve if pure electrostatic interaction can lead to the key structural features of nucleosome.
Nikolay V. Berezhnoy (2014942) +23 more
core +1 more source
The DNA Binding Protein Lsr2 from Mycobacterium tuberculosis
, 2012 Lsr2 is a small, basic DNA binding protein that is highly conserved in mycobacteria and related actinomycetes. Lsr2 is essential for growth in Mycobacterium tuberculosis and previous studies have shown that Lsr2 is involved in down-regulating a wide ...
Summers, Emma Louise
core
Caracterização das DNA topoisomerases II de Trypanosoma rangeli [PDF]
, 2012 Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia, Florianópolis, 2010DNA topoisomerases são enzimas que participam de diversos processos celulares tais como: replicação ...
Stoco, Patrícia Hermes
core
, 2004 Nucleotide excision repair (NER) in eukaryotes removes DNA base damage as an oligonucleotide in a complex series of reactions. The nature of the dual incision reactions on either side of the damaged base has been extensively investigated.
Owen-Hughes, Tom +4 more
core +1 more source
, 2019 DNA gyrase is unique among type II topoisomerases in that its DNA supercoiling activity is unidirectional. The C-terminal domain of the gyrase A subunit (GyrA-CTD) is required for this supercoiling bias.
Verdine, Gregory L. +3 more
core +1 more source
DNA superhelical density and CRP-mediated lac promoter activation
, 1991 The cyclic AMP receptor protein (CRP) functions in Escherichia coli in the regulation of several catabolite-sensitive operons. Cyclic AMP (cAMP) forms a complex with CRP which binds to specific DNA sites near the promoter of lactose operon {lacP) and ...
Lee, Hae Kyung
core
Conformational changes induced by salt in complexes of histones and superhelical nuclear DNA.
, 1981 When HeLa cells are lysed in solutions containing a non-ionic detergent and 0.75 M-NaCl, structures are released that retain many of the morphological features of nuclei.
Cook, Peter, Cook, PR, Levin, JM
core