Results 91 to 100 of about 7,352 (214)

Cleavage of circular, superhelical simian virus 40 DNA to a linear duplex by S1 nuclease

open access: yes
S(1) nuclease, the single-strand specific nuclease from Aspergillus oryzae can cleave both strands of circular covalently closed, superhelical simian virus 40 (SV40) DNA to generate unit length linear duplex molecules with intact single strands.
Berg, P., Beard, P., Morrow, J. F.
core   +1 more source

HIV chromatin is a preferred target for drugs that bind in the DNA minor groove.

open access: yesPLoS ONE, 2019
The HIV genome is rich in A but not G or U and deficient in C. This nucleotide bias controls HIV phenotype by determining the highly unusual composition of all major HIV proteins.
Clayton K Collings   +3 more
doaj   +1 more source

Functional Reciprocity of Amyloids and Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation, and Inflammation

open access: yesFrontiers in Immunology, 2020
Pathological self-assembly is a concept that is classically associated with amyloids, such as amyloid-β (Aβ) in Alzheimer's disease and α-synuclein in Parkinson's disease.
Ernest Y. Lee   +8 more
doaj   +1 more source

Determination of the number of superhelical turns in simian virus 40 DNA by gel electrophoresis

open access: yes, 1975
Closed-circular, superhelical DNA from simian virus 40 (SV40 DNA I) was treated with an excess of DNA-relaxing enzyme in the presence of increasing amounts of ethidium bromide (EtdBr).
Keller, W.
core  

Interaction of histones H1 and H1° with superhelical and linear DNA

open access: yes, 1990
By using direct competition experiments, the binding of histone H1AB (a mixture of H1A and H1B) and H1° to superhelical and linear DNA forms was studied.
Jordanka Zlatanova   +9 more
core   +1 more source

Transcriptional Silencing by TsrA in the Evolution of Pathogenic Vibrio cholerae Biotypes

open access: yesmBio, 2020
Vibrio cholerae is a globally important pathogen responsible for the severe epidemic diarrheal disease called cholera. The current and ongoing seventh pandemic of cholera is caused by El Tor strains, which have completely replaced the sixth-pandemic ...
Florence Caro   +3 more
doaj   +1 more source

Characterization of nuclear structures containing superhelical DNA

open access: yesJournal of Cell Science, 1976
ABSTRACT Structures resembling nuclei but depleted of protein may be released by gently lysing cells in solutions containing non-ionic detergents and high concentrations of salt. These nucleoids sediment in gradients containing intercalating agents in a manner characteristic of DNA that is intact, supercoiled and circular.
Cook, P, Brazell, I, Jost, E
openaire   +3 more sources

3D Printing of Conducting Polymer Hydrogels for Electrostimulation‐Assisted Tissue Engineering

open access: yesAdvanced Materials, Volume 37, Issue 36, September 11, 2025.
This review highlights nanosized inherently conducting polymers (ICPs) as promising ink constituents for 3D printing of conducting hydrogel (CH)‐based electrostimulation (ES) devices. ICP‐based ink formulation, 3D printing, and solidification strategies are discussed, along with the application of 3D‐printed ICP‐based CHs as ES platforms for regulating
Chien Minh Tran   +6 more
wiley   +1 more source

Determination of Number of Superhelical Turns in Simian Virus 40 DNA by Gel-Electrophoresis

open access: yes, 1975
Closed-circular, superhelical DNA from simian virus 40 (SV40 DNA I) was treated with an excess of DNA-relaxing enzyme in the presence of increasing amounts of ethidium bromide (EtdBr).
Keller, W.
core  

Histones and histone variant families in prokaryotes

open access: yesNature Communications
Histones are important chromatin-organizing proteins in eukaryotes and archaea. They form superhelical structures around which DNA is wrapped. Recent studies have shown that some archaea and bacteria contain alternative histones that exhibit different ...
Samuel Schwab   +8 more
doaj   +1 more source

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