Results 91 to 100 of about 11,225 (206)

Promoter prediction and annotation of microbial genomes based on DNA sequence and structural responses to superhelical stress

open access: yesBMC Bioinformatics, 2006
Background In our previous studies, we found that the sites in prokaryotic genomes which are most susceptible to duplex destabilization under the negative superhelical stresses that occur in vivo are statistically highly significantly associated with ...
Benham Craig J, Wang Huiquan
doaj   +1 more source

3D Printing of Conducting Polymer Hydrogels for Electrostimulation‐Assisted Tissue Engineering

open access: yesAdvanced Materials, Volume 37, Issue 36, September 11, 2025.
This review highlights nanosized inherently conducting polymers (ICPs) as promising ink constituents for 3D printing of conducting hydrogel (CH)‐based electrostimulation (ES) devices. ICP‐based ink formulation, 3D printing, and solidification strategies are discussed, along with the application of 3D‐printed ICP‐based CHs as ES platforms for regulating
Chien Minh Tran   +6 more
wiley   +1 more source

HIV chromatin is a preferred target for drugs that bind in the DNA minor groove.

open access: yesPLoS ONE, 2019
The HIV genome is rich in A but not G or U and deficient in C. This nucleotide bias controls HIV phenotype by determining the highly unusual composition of all major HIV proteins.
Clayton K Collings   +3 more
doaj   +1 more source

Functional Reciprocity of Amyloids and Antimicrobial Peptides: Rethinking the Role of Supramolecular Assembly in Host Defense, Immune Activation, and Inflammation

open access: yesFrontiers in Immunology, 2020
Pathological self-assembly is a concept that is classically associated with amyloids, such as amyloid-β (Aβ) in Alzheimer's disease and α-synuclein in Parkinson's disease.
Ernest Y. Lee   +8 more
doaj   +1 more source

Insights Into the Conformational Dynamics of the Cytoplasmic Domain of Metal‐Sensing Sensor Histidine Kinase ZraS

open access: yesProteins: Structure, Function, and Bioinformatics, Volume 93, Issue 9, Page 1465-1480, September 2025.
ABSTRACT ZraS is a metal sensor integral to ZraPSR, a two‐component signaling system found in enterobacters. It belongs to a family of bifunctional sensor histidine kinases (SHKs) and is speculated to sense zinc‐induced stress on the bacterial envelope.
Nilima Mahapatra   +3 more
wiley   +1 more source

Transcriptional Silencing by TsrA in the Evolution of Pathogenic Vibrio cholerae Biotypes

open access: yesmBio, 2020
Vibrio cholerae is a globally important pathogen responsible for the severe epidemic diarrheal disease called cholera. The current and ongoing seventh pandemic of cholera is caused by El Tor strains, which have completely replaced the sixth-pandemic ...
Florence Caro   +3 more
doaj   +1 more source

Torsion and bending of nucleic acids studied by subnanosecond time-resolved fluorescence depolarization of intercalated dyes [PDF]

open access: yes, 1982
Subnanosecond time‐resolved fluorescence depolarization has been used to monitor the reorientation of ethidium bromide intercalated in native DNA, synthetic polynucleotide complexes, and in supercoiled plasmid DNA.
Millar, D. P.   +2 more
core  

Physics of base-pairing dynamics in DNA

open access: yes, 2016
As a key molecule of Life, Deoxyribonucleic acid (DNA) is the focus of numbers of investigations with the help of biological, chemical and physical techniques.
Destainville, Nicolas, Manghi, Manoel
core   +3 more sources

Circularly polarized luminescence from supramolecular assemblies based on small molecules

open access: yesSmart Molecules, Volume 3, Issue 3, September 2025.
This minireview outlines the recent advances of circularly polarized luminescence (CPL)‐active supramolecular assemblies based on small molecules. It covers fundamental concepts of CPL, typical design strategies of CPL‐active materials—including the assembly of chiral luminophores, the assembly of chiral components and achiral luminophores, and the ...
Xinyu Liu   +5 more
wiley   +1 more source

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