Results 101 to 110 of about 7,436 (214)
Cell-free system for assembly of transcriptionally repressed chromatin from Drosophila Embryos [PDF]
, 1992 We descrtbe a cell·free system, derlved (rom preblastoderm DrosophÜIJ embryos. ror tbe efficient assembly of eloned DNA into chromatin. Tbe cbromatin assembly system ulilizes cndogcDous eure histones aod assembly racton aod yields loog arrays of ...
Earl Wu +3 more
core
Specific binding of chartreusin, an antitumor antibiotic, to DNA [PDF]
, 1983 Chartreusin, an antitumor and antibacterial antibiotic, was found to inhibit negatively superhelical DNA-relaxation catalyzed by prokaryotic topoisomerase I and conversion of the superhelical DNA into unit length linear form catalyzed by single-strand ...
Isono, Kiyoshi +11 more
core +1 more source
PLoS Genetics, 2012 To investigate the role of DNA topoisomerases in transcription, we have studied global gene expression in Saccharomyces cerevisiae cells deficient for topoisomerases I and II and performed single-gene analyses to support our findings.
Jakob Madsen Pedersen +9 more
doaj +1 more source
Premelting of superhelical DNA: an expression for superhelical energy [PDF]
FEBS Letters, 1981 Vologodskii, A.V. +1 more
openaire +2 more sources
Characterization of purified DNA-relaxing enzyme from human tissue culture cells [PDF]
, 1975 Superhelical simian virus 40 DNA migrates more rapidly during electrophoresis in agarose gels than covalently closed DNA free of superhelical turns (relaxed DNA). The difference in electrophoretic mobility between superhelical and relaxed DNA was used to
Keller, W., Keller, W.
core
Elucidating the DNA–Histone Interaction in Nucleosome from the DNA–Dendrimer Complex [PDF]
, 2016 The electrostatic complex of DNA with poly(amidoamine) G6 dendrimer (called “dendriplex”) is used as a model system to resolve if pure electrostatic interaction can lead to the key structural features of nucleosome.
Nikolay V. Berezhnoy (2014942) +23 more
core +1 more source
The DNA Binding Protein Lsr2 from Mycobacterium tuberculosis [PDF]
, 2012 Lsr2 is a small, basic DNA binding protein that is highly conserved in mycobacteria and related actinomycetes. Lsr2 is essential for growth in Mycobacterium tuberculosis and previous studies have shown that Lsr2 is involved in down-regulating a wide ...
Summers, Emma Louise
core
BiomoleculesEukaryotic genomic DNA is packaged into chromatin as nucleosomes, where it remains susceptible to reactive oxygen species (ROS) that generate the mutagenic lesion 8-oxo-7,8-dihydroguanine (8oxoG).
Abigayle F. Vito +12 more
doaj +1 more source
Dye titrations of covalently closed supercoiled DNA analyzed by agarose gel electrophoresis [PDF]
, 1976 We have developed a rapid electrophoretic technique for performing ethidium bromide dye titrations in cylindrical 0.7% agarose gels. The technique was used to analyze the extent of supercoiling in circular covalently closed SV40, Co1E1, and pSC101 DNA ...
DeLeys, Robert J., Jackson, David A.
core +1 more source