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Structural characterisation of chromatin remodelling intermediates supports linker DNA-dependent product inhibition as a mechanism for nucleosome spacing. [PDF]
Hughes AL +2 more
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Flipons enable genomes to learn by intermediating the exchange of energy for information. [PDF]
Herbert A.
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Cryo-EM reveals open and closed Asgard chromatin assemblies
Ranawat HM +5 more
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Circular dichroism of superhelical DNA
Biopolymers, 1971AbstractThe circular dichroism (CD) spectra of a number of superhelical DNA's have been measured. The introduction of negative superhelical turns causes an increase in magnitude of the positive band around 280 mμ, while the trough around 250mμ is little affected.
Marcos F Maestre, J C Wang
exaly +3 more sources
Probing DNA−DNA Electrostatic Friction in Tight Superhelical DNA Plies
We estimate theoretically the strength of DNA-DNA electrostatic friction forces emerging upon a slow drag of one DNA over another one in a close juxtaposition. For ideally helical DNA duplexes, this friction occurs due to correlations in electrostatic potential near the DNA surface. The latter originate from the intrinsic helicity of DNA phosphates and
Cherstvy, A.
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Generation of Superhelical Torsion by ATP-Dependent Chromatin Remodeling Activities
ATP-dependent chromatin remodeling activities participate in the alteration of chromatin structure during gene regulation. All have DNA- or chromatin-stimulated ATPase activity and many can alter the structure of chromatin; however, the means by which ...
Andrew Flaus +2 more
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Internal Dynamics of Superhelical DNA
Physical Review Letters, 2008We present the first data on the temporal kinetics of monomer mean square displacements in DNA circles with defined degrees of superhelicity. The segmental dynamics of specifically labeled DNA plasmids with superhelical densities between 0 and -0.016 was assessed by fluorescence correlation spectroscopy.
Roman, Shusterman +2 more
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Surface-Induced DNA Superhelicity
Biomacromolecules, 2000Certain biopolymers, such as DNA, have a double-stranded twisted structure and frequently exhibit a supercoiled conformation. Over the past decade, extensive conformational analyses of different biopolymers have been performed using atomic force microscopy.
Y S, Velichko +2 more
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Thermodynamic properties of superhelical DNAs
Biochemistry, 1975Binding isotherms of ethidium to the superhelical DNA from phage PM2, and to PM2 DNA containing -1 single-chain scission per molecule, have been determined at six temperatures from 2.5 to 50 degrees, in 3M CsCl-0.01 M Na3EDTA. Spectrophotometric measurements in both the visible and ultraviolet (uv) regions were used to obtain the binding isotherms. The
T S, Hsieh, J C, Wang
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