Results 171 to 180 of about 11,225 (206)
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Probing DNA−DNA Electrostatic Friction in Tight Superhelical DNA Plies
The Journal of Physical Chemistry B, 2009We estimate theoretically the strength of DNA-DNA electrostatic friction forces emerging upon a slow drag of one DNA over another one in a close juxtaposition. For ideally helical DNA duplexes, this friction occurs due to correlations in electrostatic potential near the DNA surface. The latter originate from the intrinsic helicity of DNA phosphates and
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Structures of Homopurine-homopyrimidine Tract in Superhelical DNA
Journal of Biomolecular Structure and Dynamics, 1986For homopurine-homopyrimidine tracts in superhelical DNA, we propose a structure involving Watson-Crick and Hoogsteen paired triple helixes, hairpin loops and unstructured domains. Topologically, the whole structure is equivalent to an open region. The proposed structure is consistent with available S1 cleavage, pH and alkylation data and energetics ...
V I, Lyamichev +2 more
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Superhelical DNA studied by solution scattering and computer models
Genetica, 1999We present here recent results on the structure of superhelical DNA and its changes with salt concentration between 0.01 and 1.5 M NaCl. Scattering curves of two different superhelical DNAs were determined by static light scattering. The measured radii of gyration do not change significantly with salt concentration.
J, Langowski +4 more
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1985
When a duplex DNA molecule is covalently closed into a circle, conservation of the antiparallel chemical (5′–3′) orientations of the two strands dictates that the resulting ring molecule must have the topological structure of two closed, interlinked circles. This fixes the value of the molecular linking number Lk.
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When a duplex DNA molecule is covalently closed into a circle, conservation of the antiparallel chemical (5′–3′) orientations of the two strands dictates that the resulting ring molecule must have the topological structure of two closed, interlinked circles. This fixes the value of the molecular linking number Lk.
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Alteration of superhelical state of DNA by aluminium (Al)
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression, 1993The effect of aluminium (Al) on the supercoiled state of pUC18 DNA was studied by ethidium bromide fluorescence and agarose gel electrophoresis. Al at physiologically relevant concentrations relaxed the intact supercoiled DNA as well as the topoisomers induced by chloroquine. EDTA prevented the unwinding effect of Al on supercoiled DNA.
K S, Rao +3 more
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Attachment of nascent RNA molecules to superhelical DNA
Journal of Molecular Biology, 1975Comparisons are made of the attachment of nascent RNA molecules synthesized in vitro with Escherichia coli RNA polymerase on native bacteriophage PM2 DNA, a double-helical circular DNA with −110 superhelical twists, and on a derivative of this DNA with no superhelical twists.
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Modeling superhelical DNA: recent analytical and dynamic approaches
Current Opinion in Structural Biology, 1995During the past year, a variety of diverse and complementary approaches have been presented for modeling superhelical DNA, offering new physical and biological insights into fundamental functional processes of DNA. Analytical approaches have probed deeper into the effects of entropy and thermal fluctuations on DNA structure and on various topological ...
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Superhelical DNA in yeast chromosomes
Experimental Cell Research, 1977S J, McCready, B S, Cox, C S, McLaughlin
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