Results 1 to 10 of about 947,078 (263)

Force steps during viral DNA packaging ? [PDF]

open access: yesJournal of the Mechanics and Physics of Solids, 2003
Biophysicists and structural biologists increasingly acknowledge the role played by the mechanical properties of macromolecules as a critical element in many biological processes.
Alberts   +29 more
core   +6 more sources

DNA vaccines for viral diseases [PDF]

open access: yesBrazilian Journal of Medical and Biological Research, 1999
DNA plasmids encoding foreign proteins may be used as immunogens by direct intramuscular injection alone, or with various adjuvants and excipients, or by delivery of DNA-coated gold particles to the epidermis through biolistic immunization. Antibody, helper T lymphocyte, and cytotoxic T lymphocyte (CTL) responses have been induced in laboratory and ...
Donnelly, J.J., Ulmer, J.B.
openaire   +7 more sources

Viral MicroRNA Effects on Pathogenesis of Polyomavirus SV40 Infections in Syrian Golden Hamsters [PDF]

open access: yes, 2014
Shaojie Zhang, Vojtech Sroller, Preeti Zanwar, Steven J. Halvorson, Nadim J. Ajami, Corey W. Hecksel, Jody L. Swain, Connie Wong, Janet S. Butel, Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, United States
Ajami, Nadim J.   +10 more
core   +6 more sources

Epigenetic control of Epstein–Barr virus transcription – relevance to viral life cycle? [PDF]

open access: yes, 2013
DNA methylation normally leads to silencing of gene expression but Epstein–Barr virus (EBV) provides an exception to the epigenetic paradigm. DNA methylation is absolutely required for the expression of many viral genes.
Sinclair, Alison J
core   +2 more sources

Membrane-assisted viral DNA ejection [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - General Subjects, 2017
Genome packaging and delivery are fundamental steps in the replication cycle of all viruses. Icosahedral viruses with linear double-stranded DNA (dsDNA) usually package their genome into a preformed, rigid procapsid using the power generated by a virus-encoded packaging ATPase.
Santos Pérez, Isaac   +5 more
openaire   +5 more sources

Sequence organization of feline leukemis virus DNA in infected cells [PDF]

open access: yes, 1980
A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W.   +3 more
core   +1 more source

Early and Highly Suppressive ART are Main Factors Associated with Low Viral Reservoir in European Perinatally HIV Infected Children [PDF]

open access: yes, 2018
BACKGROUND: Future strategies aiming to achieve HIV-1 remission are likely to target individuals with small reservoir size. SETTING: We retrospectively investigated factors associated with HIV-1 DNA levels in European, perinatally HIV-infected ...
Babiker, Abdel   +22 more
core   +2 more sources

Cellular Sensing of Viral DNA and Viral Evasion Mechanisms [PDF]

open access: yesAnnual Review of Microbiology, 2014
Mammalian cells detect foreign DNA introduced as free DNA or as a result of microbial infection, leading to the induction of innate immune responses that block microbial replication and the activation of mechanisms that epigenetically silence the genes encoded by the foreign DNA.
David M. Knipe, Megan H. Orzalli
openaire   +3 more sources

Replication of Epstein-Barr Viral DNA [PDF]

open access: yesCold Spring Harbor Perspectives in Biology, 2013
Epstein-Barr virus (EBV) is a paradigm for human tumor viruses: it is the first virus recognized to cause cancer in people; it causes both lymphomas and carcinomas; yet these tumors arise infrequently given that most people in the world are infected with the virus. EBV is maintained extrachromosomally in infected normal and tumor cells.
Hammerschmidt, W., Sugden, B.
openaire   +4 more sources

Nuclear Import of Viral DNA Genomes [PDF]

open access: yesTraffic, 2003
The genomes of many viruses traffic into the nucleus, where they are either integrated into host chromosomes or maintained as episomal DNA and then transcriptionally activated or silenced. Here, we discuss the existing evidence on how the lentiviruses, adenoviruses, herpesviruses, hepadnaviruses and autonomous parvoviruses enter the nucleus.
Greber, U F, Fassati, A
openaire   +4 more sources

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