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Global diversity and biogeography of DNA viral communities in activated sludge systems. [PDF]

open access: yesMicrobiome, 2023
Background Activated sludge (AS) systems in wastewater treatment plants (WWTPs) harbor enormous viruses that regulate microbial metabolism and nutrient cycling, significantly influencing the stability of AS systems.
Fan X   +10 more
europepmc   +2 more sources

CXCL10 Chemokine: A Critical Player in RNA and DNA Viral Infections. [PDF]

open access: yesViruses, 2022
Chemokines constitute a group of small, secreted proteins that regulate leukocyte migration and contribute to their activation. Chemokines are crucial inflammatory mediators that play a key role in managing viral infections, during which the profile of ...
Elemam NM, Talaat IM, Maghazachi AA.
europepmc   +2 more sources

Efficient Transient Expression of Recombinant Proteins Using DNA Viral Vectors in Freshwater Microalgal Species. [PDF]

open access: yesFront Plant Sci, 2021
The increase in the world population, the advent of new infections and health issues, and the scarcity of natural biological products have spotlighted the importance of recombinant protein technology and its large-scale production in a cost-effective ...
Malla A   +3 more
europepmc   +2 more sources

Viral evasion of intracellular DNA and RNA sensing

open access: yesNature Reviews Microbiology, 2016
The co-evolution of viruses with their hosts has led to the emergence of viral pathogens that are adept at evading or actively suppressing host immunity.
Ying Kai Chan, Michaela U Gack
exaly   +2 more sources

Marine DNA Viral Macro- and Microdiversity from Pole to Pole. [PDF]

open access: yesCell, 2019
Gregory AC   +33 more
europepmc   +2 more sources

Modulation of the functional interfaces between retroviral intasomes and the human nucleosome

open access: yesmBio, 2023
Infection by retroviruses as HIV-1 requires the stable integration of their genome into the host cells. This process needs the formation of integrase (IN)-viral DNA complexes, called intasomes, and their interaction with the target DNA wrapped around ...
E. Mauro   +18 more
doaj   +1 more source

Replication Compartments—The Great Survival Strategy for Epstein–Barr Virus Lytic Replication

open access: yesMicroorganisms, 2022
During Epstein–Barr virus (EBV) lytic replication, viral DNA synthesis is carried out in viral replication factories called replication compartments (RCs), which are located at discrete sites in the nucleus.
Atsuko Sugimoto
doaj   +1 more source

HSV-1 DNA Replication—Coordinated Regulation by Viral and Cellular Factors

open access: yesViruses, 2021
DNA replication is an integral step in the herpes simplex virus type 1 (HSV-1) life cycle that is coordinated with the cellular DNA damage response, repair and recombination of the viral genome, and viral gene transcription.
Jessica E. Packard, Jill A. Dembowski
doaj   +1 more source

Highly pathogenic avian influenza A/Guangdong/17SF003/2016 is immunogenic and induces cross-protection against antigenically divergent H7N9 viruses

open access: yesnpj Vaccines, 2021
Avian influenza A(H7N9) epidemics have a fatality rate of approximately 40%. Previous studies reported that low pathogenic avian influenza (LPAI)-derived candidate vaccine viruses (CVVs) are poorly immunogenic.
Peter Radvak   +10 more
doaj   +1 more source

Inhibition of histone methyltransferase SETD8 represses DNA virus replication

open access: yesCell Insight, 2022
Multiple diseases, such as cancer and neural degeneration diseases, are related with the latent infection of DNA viruses. However, it is still difficult to clean up the latent DNA viruses and new anti-viral strategies are critical for disease treatment ...
Lin Chen   +6 more
doaj   +1 more source

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