Results 11 to 20 of about 548,105 (272)
Parvovirus b19 DNA CpG dinucleotide methylation and epigenetic regulation of viral expression. [PDF]
PLoS ONE, 2012 CpG DNA methylation is one of the main epigenetic modifications playing a role in the control of gene expression. For DNA viruses whose genome has the ability to integrate in the host genome or to maintain as a latent episome, a correlation has been ...
Francesca Bonvicini +4 more
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Dangerous Liaisons: Long-Term Replication with an Extrachromosomal HPV Genome
Viruses, 2021 Papillomaviruses cause persistent, and usually self-limiting, infections in the mucosal and cutaneous surfaces of the host epithelium. However, in some cases, infection with an oncogenic HPV can lead to cancer.
Alix Warburton +2 more
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Membrane-assisted viral DNA ejection [PDF]
Biochimica et Biophysica Acta (BBA) - General Subjects, 2017 Genome packaging and delivery are fundamental steps in the replication cycle of all viruses. Icosahedral viruses with linear double-stranded DNA (dsDNA) usually package their genome into a preformed, rigid procapsid using the power generated by a virus-encoded packaging ATPase.
Santos Pérez, Isaac +5 more
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Cellular Sensing of Viral DNA and Viral Evasion Mechanisms [PDF]
Annual Review of Microbiology, 2014 Mammalian cells detect foreign DNA introduced as free DNA or as a result of microbial infection, leading to the induction of innate immune responses that block microbial replication and the activation of mechanisms that epigenetically silence the genes encoded by the foreign DNA.
David M. Knipe, Megan H. Orzalli
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Viral DNA Polymerase Inhibitors [PDF]
, 2009 ispartof: pages:481 ...
Andrei, Graciela +2 more
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Viral oncoproteins target the DNA methyltransferases [PDF]
Oncogene, 2006 Small DNA tumour viruses have evolved a number of mechanisms to drive nondividing cells into S phase. Virally encoded oncoproteins such as adenovirus E1A and human papillomavirus (HPV) E7 can bind an array of cellular proteins to override proliferation arrest. The DNA methyltransferase Dnmt1 is the major mammalian enzyme responsible for maintaining CpG
Burgers, T +7 more
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ESC Heart Failure, 2021 Aims Parvovirus B19 (B19V) is often assumed to be a cause of dilated cardiomyopathy (DCM), based on the quantification of B19V DNA in endomyocardial biopsies (EMB).
Anne Russcher +5 more
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Replication of Epstein-Barr Viral DNA [PDF]
Cold Spring Harbor Perspectives in Biology, 2013 Epstein-Barr virus (EBV) is a paradigm for human tumor viruses: it is the first virus recognized to cause cancer in people; it causes both lymphomas and carcinomas; yet these tumors arise infrequently given that most people in the world are infected with the virus. EBV is maintained extrachromosomally in infected normal and tumor cells.
Hammerschmidt, W., Sugden, B.
openaire +4 more sources
Nuclear Import of Viral DNA Genomes [PDF]
Traffic, 2003 The genomes of many viruses traffic into the nucleus, where they are either integrated into host chromosomes or maintained as episomal DNA and then transcriptionally activated or silenced. Here, we discuss the existing evidence on how the lentiviruses, adenoviruses, herpesviruses, hepadnaviruses and autonomous parvoviruses enter the nucleus.
Greber, U F, Fassati, A
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Virology Journal, 2021 Background Quality of the nucleic acids extracted from Formalin Fixed Paraffin Embedded (FFPE) samples largely depends on pre-analytic, fixation and storage conditions.
Sara Nicolás-Párraga +8 more
doaj +1 more source