Results 21 to 30 of about 874,984 (309)
Membrane-assisted viral DNA ejection [PDF]
Biochimica et Biophysica Acta (BBA) - General Subjects, 2017 Genome packaging and delivery are fundamental steps in the replication cycle of all viruses. Icosahedral viruses with linear double-stranded DNA (dsDNA) usually package their genome into a preformed, rigid procapsid using the power generated by a virus-encoded packaging ATPase.
Santos Pérez, Isaac +5 more
openaire +5 more sources
Sequence organization of feline leukemis virus DNA in infected cells [PDF]
, 1980 A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W. +3 more
core +1 more source
Cellular Sensing of Viral DNA and Viral Evasion Mechanisms [PDF]
Annual Review of Microbiology, 2014 Mammalian cells detect foreign DNA introduced as free DNA or as a result of microbial infection, leading to the induction of innate immune responses that block microbial replication and the activation of mechanisms that epigenetically silence the genes encoded by the foreign DNA.
David M. Knipe, Megan H. Orzalli
openaire +3 more sources
Visualization of DNA G-quadruplexes in herpes simplex virus 1-infected cells [PDF]
, 2016 We have previously shown that clusters of guanine quadruplex (G4) structures can form in the human herpes simplex-1 (HSV-1) genome. Here we used immunofluorescence and immune-electron microscopy with a G4-specific monoclonal antibody to visualize G4 ...
Artusi, Sara +6 more
core +1 more source
Viral DNA Polymerase Inhibitors [PDF]
, 2009 ispartof: pages:481 ...
Andrei, Graciela +2 more
openaire +3 more sources
Viral oncoproteins target the DNA methyltransferases [PDF]
Oncogene, 2006 Small DNA tumour viruses have evolved a number of mechanisms to drive nondividing cells into S phase. Virally encoded oncoproteins such as adenovirus E1A and human papillomavirus (HPV) E7 can bind an array of cellular proteins to override proliferation arrest. The DNA methyltransferase Dnmt1 is the major mammalian enzyme responsible for maintaining CpG
Burgers, T +7 more
openaire +5 more sources
The human papillomavirus 16 E2 protein is stabilised in S phase [PDF]
, 2009 The human papillomavirus 16 E2 protein regulates transcription from, and replication of, the viral genome and is also required for segregation of the viral genome via interaction with mitotic bodies.
Dornan, E.S. +3 more
core +1 more source
Replication of Epstein-Barr Viral DNA [PDF]
Cold Spring Harbor Perspectives in Biology, 2013 Epstein-Barr virus (EBV) is a paradigm for human tumor viruses: it is the first virus recognized to cause cancer in people; it causes both lymphomas and carcinomas; yet these tumors arise infrequently given that most people in the world are infected with the virus. EBV is maintained extrachromosomally in infected normal and tumor cells.
Hammerschmidt, W., Sugden, B.
openaire +4 more sources
Nuclear Import of Viral DNA Genomes [PDF]
Traffic, 2003 The genomes of many viruses traffic into the nucleus, where they are either integrated into host chromosomes or maintained as episomal DNA and then transcriptionally activated or silenced. Here, we discuss the existing evidence on how the lentiviruses, adenoviruses, herpesviruses, hepadnaviruses and autonomous parvoviruses enter the nucleus.
Greber, U F, Fassati, A
openaire +4 more sources
mBio, 2012 Drastic reorganization of the nucleus is a hallmark of herpesvirus replication. This reorganization includes the formation of viral replication compartments, the subnuclear structures in which the viral DNA genome is replicated.
Blair L. Strang +3 more
doaj +1 more source