Results 21 to 30 of about 751,138 (168)
mBio, 2012 Drastic reorganization of the nucleus is a hallmark of herpesvirus replication. This reorganization includes the formation of viral replication compartments, the subnuclear structures in which the viral DNA genome is replicated.
Blair L. Strang +3 more
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PLoS ONE, 2012 Although HCMV encodes many genes required for the replication of its DNA genome, no HCMV-encoded orthologue of the origin binding protein, which has been identified in other herpesviruses, has been identified.
Tamara Evans Braun +2 more
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Replication of Epstein-Barr Viral DNA [PDF]
Cold Spring Harbor Perspectives in Biology, 2013 Epstein-Barr virus (EBV) is a paradigm for human tumor viruses: it is the first virus recognized to cause cancer in people; it causes both lymphomas and carcinomas; yet these tumors arise infrequently given that most people in the world are infected with the virus. EBV is maintained extrachromosomally in infected normal and tumor cells.
Wolfgang, Hammerschmidt, Bill, Sugden
openaire +2 more sources
Involvement of Host ATR-CHK1 Pathway in Hepatitis B Virus Covalently Closed Circular DNA Formation
mBio, 2020 The covalently closed circular (CCC) DNA of hepatitis B virus (HBV) functions as the only viral transcriptional template capable of producing all viral RNA species and is essential to initiate and sustain viral replication.
Jun Luo +5 more
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Virology Journal, 2021 Background Quality of the nucleic acids extracted from Formalin Fixed Paraffin Embedded (FFPE) samples largely depends on pre-analytic, fixation and storage conditions.
Sara Nicolás-Párraga +8 more
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Chinese Giant Salamander Iridovirus 025L Is a Viral Essential Gene
Viruses, 2023 Ranavirus is a large nucleocytoplasmic DNA virus. Chinese giant salamander iridovirus (CGSIV) belongs to the ranavirus genus, and its replication involves a series of essential viral genes.
Zijing Liu +7 more
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, 2010 Chromosome organization plays a key role in many biological processes. In viruses genome organization is essential for the packaging and releasing of the genome as well as for maintaining the stability of the viral capsid. This organization varies across different families and is highly dependent on the virus morphogenetic pathway (Casjens, 1997).
Arsuaga, Javier +2 more
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Force steps during viral DNA packaging? [PDF]
Journal of the Mechanics and Physics of Solids, 2003 Biophysicists and structural biologists increasingly acknowledge the role played by the mechanical properties of macromolecules as a critical element in many biological processes. This change has been brought about, in part, by the advent of single molecule biophysics techniques that have made it possible to exert piconewton forces on key ...
Purohit, Prashant K. +2 more
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Advances in Cancer Biology - MetastasisWe have investigated the expression of selected genes and miRNAs that have been found to be associated with human cancer-stem cells for their involvement in the neoplastic evolution of our AGMK1-9T7 cell line from a non-tumorigenic status at passage (p ...
Andrew M. Lewis, Jr. +7 more
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ATRX promotes maintenance of herpes simplex virus heterochromatin during chromatin stress
eLife, 2018 The mechanisms by which mammalian cells recognize and epigenetically restrict viral DNA are not well defined. We used herpes simplex virus with bioorthogonally labeled genomes to detect host factors recruited to viral DNA shortly after its nuclear entry ...
Joseph M Cabral +2 more
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