Results 31 to 40 of about 3,810,700 (346)

HSV-1 not only in human vestibular ganglia but also in the vestibular labyrinth [PDF]

, 2001
Reactivation of herpes simplex virus type 1 (HSV-1) in the vestibular ganglion (VG) is the suspected cause of vestibular neuritis (VN). Recent studies reported the presence of HSV-1 DNA not only in human VGs but also in vestibular nuclei, a finding that ...
Arbusow, Viktor, Brandt, Thomas, Mascolo, Andrea, Strupp, Michael, Theil, Diethilde   +4 more
core   +1 more source

Parvovirus B19 DNA detectable in hearts of patients with dilated cardiomyopathy, but absent or inactive in blood

ESC Heart Failure, 2021
Aims Parvovirus B19 (B19V) is often assumed to be a cause of dilated cardiomyopathy (DCM), based on the quantification of B19V DNA in endomyocardial biopsies (EMB).
Anne Russcher, Job Verdonschot, Marijke W.A. Molenaar‐de Backer, Stephane R.B. Heymans, Aloys C.M. Kroes, Hans L. Zaaijer   +5 more
doaj   +1 more source

Designer DNA architecture offers precise and multivalent spatial pattern-recognition for viral sensing and inhibition

bioRxiv, 2019
DNA, when folded into nanostructures with a specific shape, is capable of spacing and arranging binding sites into a complex geometric pattern with nanometre precision.
Paul S. Kwon, Shaokang Ren, S. Kwon, Megan E. Kizer, L. Kuo, Mo Xie, Dan Zhu, Feng Zhou, Fuming Zhang, Domyoung Kim, Keith Fraser, L. Kramer, N. Seeman, J. Dordick, R. Linhardt, J. Chao, Xing Wang   +16 more
semanticscholar   +1 more source

DNA vaccination against persistent viral infection [PDF]

Journal of Virology, 1995
This study shows that DNA vaccination can confer protection against a persistent viral infection by priming CD8+ cytotoxic T lymphocytes (CTL). Adult BALB/c (H-2d) mice were injected intramuscularly with a plasmid expressing the nucleoprotein (NP) gene of lymphocytic choriomeningitis virus (LCMV) under the control of the cytomegalovirus promoter.
L P, Martins, L L, Lau, M S, Asano, R, Ahmed   +3 more
openaire   +2 more sources

Depletion of cellular pre-replication complex factors results in increased human cytomegalovirus DNA replication.

PLoS ONE, 2012
Although HCMV encodes many genes required for the replication of its DNA genome, no HCMV-encoded orthologue of the origin binding protein, which has been identified in other herpesviruses, has been identified.
Tamara Evans Braun, Emma Poole, John Sinclair   +2 more
doaj   +1 more source

Broad Surveys of DNA Viral Diversity Obtained through Viral Metagenomics of Mosquitoes

PLoS ONE, 2011
Viruses are the most abundant and diverse genetic entities on Earth; however, broad surveys of viral diversity are hindered by the lack of a universal assay for viruses and the inability to sample a sufficient number of individual hosts.
T. Ng, D. Willner, Y. Lim, Robert Schmieder, B. Chau, Christina Nilsson, S. Anthony, Y. Ruan, F. Rohwer, M. Breitbart   +9 more
semanticscholar   +1 more source

Host Cell Nucleolin Is Required To Maintain the Architecture of Human Cytomegalovirus Replication Compartments

mBio, 2012
Drastic reorganization of the nucleus is a hallmark of herpesvirus replication. This reorganization includes the formation of viral replication compartments, the subnuclear structures in which the viral DNA genome is replicated.
Blair L. Strang, Steeve Boulant, Tomas Kirchhausen, Donald M. Coen   +3 more
doaj   +1 more source

Involvement of Host ATR-CHK1 Pathway in Hepatitis B Virus Covalently Closed Circular DNA Formation

mBio, 2020
The covalently closed circular (CCC) DNA of hepatitis B virus (HBV) functions as the only viral transcriptional template capable of producing all viral RNA species and is essential to initiate and sustain viral replication.
Jun Luo, Laurie Luckenbaugh, Hui Hu, Zhipeng Yan, Lu Gao, Jianming Hu   +5 more
doaj   +1 more source

Human DNA decays faster with time than viral dsDNA: an analysis on HPV16 using pathology archive samples spanning 85 years

Virology Journal, 2021
Background Quality of the nucleic acids extracted from Formalin Fixed Paraffin Embedded (FFPE) samples largely depends on pre-analytic, fixation and storage conditions.
Sara Nicolás-Párraga, Montserrat Torres, Laia Alemany, Ana Félix, Eugenia Cruz, Silvia de Sanjosé, Francesc Xavier Bosch, Ignacio G. Bravo, the RIS HPV TT study groups   +8 more
doaj   +1 more source

Upstream-binding factor is sequestered into herpes simplex virus type 1 replication compartments [PDF]

, 2009
Previous reports have shown that adenovirus recruits nucleolar protein upstream-binding factor (UBF) into adenovirus DNA replication centres. Here, we report that despite having a different mode of viral DNA replication, herpes simplex virus type 1 (HSV ...
Ahmed, Bertrand, Besse, Boehmer, Boisvert, Cheng, Copenhaver, D. A. Matthews, de Jong, Everett, Grummt, Hiscox, Kuhn, Lawrence, Liu, Lymberopoulos, Mears, Meraner, N. D. Stow, Pederson, Puvion-Dutilleul, Roller, Stow, Strang, Taylor, V. C. Evans   +25 more
core   +2 more sources