Results 51 to 60 of about 751,138 (168)
Scientific Reports, 2023 In this study, non-electrically controlled SalivaDirect loop-mediated isothermal amplification (NEC-SD-LAMP), which can detect infections by amplifying viral DNA expression in saliva without using electrical control systems, was developed. By this method,
Yusuke Kimura, Masashi Ikeuchi
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Improving DNA Vaccines Targeting Viral Infection
Intervirology, 2000 DNA vaccination techniques have been recently under intensive investigation both preclinically and in human studies aimed at impacting viral infection. Collectively, DNA vaccines expressing viral antigens induce both antigen-specific humoral and cellular immune responses which in model systems are capable of impacting viral infection.
J I, Sin, D B, Weiner
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Repulsive DNA-DNA Interactions Accelerate Viral DNA Packaging in Phage Phi29 [PDF]
Physical Review Letters, 2014 We use optical tweezers to study the effect of attractive versus repulsive DNA-DNA interactions on motor-driven viral packaging. Screening of repulsive interactions accelerates packaging, but induction of attractive interactions by spermidine(3+) causes heterogeneous dynamics.
Nicholas, Keller +4 more
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Different patterns of HIV-1 DNA after therapy discontinuation
BMC Infectious Diseases, 2005 Background By persisting in infected cells for a long period of time, proviral HIV-1 DNA can represent an alternative viral marker to RNA viral load during the follow-up of HIV-1 infected individuals.
Ghinelli Florio +5 more
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Brd4 is displaced from HPV replication factories as they expand and amplify viral DNA.
PLoS Pathogens, 2013 Replication foci are generated by many viruses to concentrate and localize viral DNA synthesis to specific regions of the cell. Expression of the HPV16 E1 and E2 replication proteins in keratinocytes results in nuclear foci that recruit proteins ...
Nozomi Sakakibara +7 more
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Retrovirology, 2005 Background In addition to mediating the integration process, HIV-1 integrase (IN) has also been implicated in different steps during viral life cycle including reverse transcription and viral DNA nuclear import. Although the karyophilic property of HIV-1
Fowke Keith R +3 more
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Characterization of the hepatitis B virus DNA detected in urine of chronic hepatitis B patients
BMC Gastroenterology, 2018 Background Detection of human hepatitis B virus (HBV) DNA in the urine of patients with chronic hepatitis B infection (CHB) has been reported previously, suggesting urine could provide a potential route of horizontal HBV transmission.
Surbhi Jain +10 more
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PLoS ONE, 2014 Resting CD4+ T cells are a reservoir of latent HIV-1. Understanding the turnover of HIV DNA in these cells has implications for the development of eradication strategies.
Jeanette C Reece +9 more
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PLoS Pathogens, 2020 In plants, cytosine DNA methylation is an efficient defense mechanism against geminiviruses, since methylation of the viral genome results in transcriptional gene silencing (TGS).
Yuzhen Mei +4 more
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Packaging DNA Origami into Viral Protein Cages [PDF]
, 2018 The DNA origami technique is a widely used method to create customized, complex, spatially well-defined two-dimensional (2D) and three-dimensional (3D) DNA nanostructures. These structures have huge potential to serve as smart drug-delivery vehicles and molecular devices in various nanomedical and biotechnological applications.
Veikko, Linko +2 more
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