Purification of Viral DNA for the Identification of Associated Viral and Cellular Proteins [PDF]
The goal of this protocol is to isolate herpes simplex virus type 1 (HSV-1) DNA from infected cells for the identification of associated viral and cellular proteins by mass spectrometry. Although proteins that interact with viral genomes play major roles in determining the outcome of infection, a comprehensive analysis of viral genome associated ...
Jill A. Dembowski, Neal A. DeLuca
openaire +3 more sources
A review of DNA viral infections in psittacine birds.
To date, several DNA viral infections have been reported in psittacine birds. Psittacine beak and feather disease (PBFD) is characterized by symmetric feather dystrophy and loss and development of beak deformities.
H. Katoh, H. Ogawa, K. Ohya, H. Fukushi
semanticscholar +1 more source
VirSorter2: a multi-classifier, expert-guided approach to detect diverse DNA and RNA viruses
Viruses are a significant player in many biosphere and human ecosystems, but most signals remain “hidden” in metagenomic/metatranscriptomic sequence datasets due to the lack of universal gene markers, database representatives, and insufficiently advanced
Jiarong Guo +10 more
semanticscholar +1 more source
Involvement of Host ATR-CHK1 Pathway in Hepatitis B Virus Covalently Closed Circular DNA Formation
The covalently closed circular (CCC) DNA of hepatitis B virus (HBV) functions as the only viral transcriptional template capable of producing all viral RNA species and is essential to initiate and sustain viral replication.
Jun Luo +5 more
doaj +1 more source
Chinese Giant Salamander Iridovirus 025L Is a Viral Essential Gene
Ranavirus is a large nucleocytoplasmic DNA virus. Chinese giant salamander iridovirus (CGSIV) belongs to the ranavirus genus, and its replication involves a series of essential viral genes.
Zijing Liu +7 more
doaj +1 more source
Upstream-binding factor is sequestered into herpes simplex virus type 1 replication compartments [PDF]
Previous reports have shown that adenovirus recruits nucleolar protein upstream-binding factor (UBF) into adenovirus DNA replication centres. Here, we report that despite having a different mode of viral DNA replication, herpes simplex virus type 1 (HSV ...
Ahmed +25 more
core +2 more sources
Designer DNA nanostructures for viral inhibition [PDF]
Emerging viral diseases can substantially threaten national and global public health. Central to our ability to successfully tackle these diseases is the need to quickly detect the causative virus and neutralize it efficiently. Here we present the rational design of DNA nanostructures to inhibit dengue virus infection.
Shaokang Ren +8 more
openaire +2 more sources
The human respiratory tract is constantly exposed to a wide variety of viruses, microbes and inorganic particulates from environmental air, water and food.
D. Willner +9 more
semanticscholar +1 more source
Metagenomic compendium of 189,680 DNA viruses from the human gut microbiome
Bacteriophages have important roles in the ecology of the human gut microbiome but are under-represented in reference databases. To address this problem, we assembled the Metagenomic Gut Virus catalogue that comprises 189,680 viral genomes from 11,810 ...
Stephen Nayfach +10 more
semanticscholar +1 more source
Nucleotide-dependent DNA gripping and an end-clamp mechanism regulate the bacteriophage T4 viral packaging motor. [PDF]
ATP-powered viral packaging motors are among the most powerful biomotors known. Motor subunits arranged in a ring repeatedly grip and translocate the DNA to package viral genomes into capsids.
Alam, Istiaq +4 more
core +3 more sources

