Results 61 to 70 of about 3,377 (106)

[Neutrophil-derived Microvesicles Regulate DNA Methylation of the <i>LINE1</i> Gene in Human Fibroblast-like Synoviocytes]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Zhao Z, Tang M, Liang Y, Zhang T, Ren Q, Cheng Q, Xiong Y, Ma K, Zhan D.   +8 more
europepmc   +1 more source

[Identification of SORD as A Key Gene Mediating Osimertinib Primary Resistance 
in EGFR-Mutant Lung Adenocarcinoma via Machine Learning and Methylomics]. [PDF]

Zhongguo Fei Ai Za Zhi
Liang G, Wu H, Jia C, Gao P, Zhang Z, Chen C, Li Y, Liu H, Chen J.   +8 more
europepmc   +1 more source

糖尿病性骨质疏松与脂肪干细胞成骨分化能力损害机制研究进展

Zhongshan Daxue xuebao. Yixue kexue ban
糖尿病（DM）患者长期高血糖所致骨质疏松及骨愈合延迟等骨骼并发症已成为显著降低其生活质量的临床难题，其核心机制与脂肪干细胞（ADSCs）成骨分化能力受损密切相关。在骨组织工程中，ADSCs因取材微创、增殖迅速及多向分化能力被视为骨缺损修复的种子细胞，但DM病理环境显著抑制了ADSCs的成骨潜能，进而影响了糖尿病骨病的治疗效率。因此，探索高糖环境下ADSCs成骨能力障碍的深层机制对优化糖尿病骨病的治疗策略具有重要意义。本文系统回顾并总结了高糖环境中ADSCs迁移能力下降、增殖活性降低 ...
韩芳, 田峻
doaj  

[Analysis of urine biomarkers in urothelial carcinoma based on untargeted metabolomics]. [PDF]

Se Pu
Liu S, Wang M, Wang W.
europepmc   +1 more source

[Role of m6A methylation modification in photoaging and ultraviolet-induced skin cancers]. [PDF]

Zhong Nan Da Xue Xue Bao Yi Xue Ban
Hou Y, Zhang X, Liu J, Wu J.
europepmc   +1 more source

[Tripeptide polymer-based cell-imprinted hydrogels for high-efficiency circulating tumor cell capture]. [PDF]

Se Pu
Sun W, Zhang Z, Zhao X, Chen J, Qing G.
europepmc   +1 more source

水凝胶微珠在早期无创诊断结直肠癌的研究进展

Zhongguo shiyan zhenduanxue
结直肠癌（Colorectal cancer，CRC）是全球高发病率和高死亡率的恶性肿瘤之一，早期诊断对改善患者预后至关重要。然而，传统诊断方法如结肠镜检查和粪便潜血试验（Fecal occult blood test，FOBT）存在侵入性、灵敏度不足等局限性。水凝胶微珠技术因其优异的生物相容性、高负载能力和可调控的物理化学性质，在 CRC早期无创诊断中展现出巨大潜力。本文综述了水凝胶微珠的技术原理、制备方法（如微流体技术、乳化法、电喷雾、光刻法和 3D打印）及其在 CRC核酸标志物（如基因突变、甲基化
王少妍, 秦宇, 付渤钧, 张海山
doaj  

[Performance of Plasma Multigene Methylation Testing in Early Diagnosis of Colorectal Cancer]. [PDF]

Sichuan Da Xue Xue Bao Yi Xue Ban
Sheng N, Guo Y, Hou X, Wang Y, Xu Y.
europepmc   +1 more source

[Advances in basic and experimental diagnostic research on liver diseases in 2025​]. [PDF]

Zhonghua Gan Zang Bing Za Zhi
Chen DB, Yang RF, Chen HS.
europepmc   +1 more source

[Association between <i>MLPH</i> gene hypermethylation in peripheral blood and coronary heart disease]. [PDF]

Nan Fang Yi Ke Da Xue Xue Bao
Jin J, Wang F, Zhu L, Zhao X, Wang J, Zhu C, Yang R.   +6 more
europepmc   +1 more source