Results 201 to 210 of about 1,985,752 (333)

Author response: ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins

Mathew J. Thayer, Michael B. Heskett, Leslie G. Smith, Paul T. Spellman, Phillip A. Yates   +4 more
openalex   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

The concentration of single-stranded DNA-binding proteins is a critical factor in recombinase polymerase amplification (RPA), as revealed by insights from an open-source system. [PDF]

PeerJ
Cordoba-Andrade F, Peralta-Castro A, García-Medel PL, Castro-Torres E, Gonzalez-Gonzalez R, Castro-Lara AY, Mora Garduño JD, Raygoza CD, Baruch-Torres N, Peñafiel-Ayala A, Diaz-Quezada C, Cardona-Felix CS, Guzman Chavez F, Trasviña-Arenas CH, Sotelo-Mundo RR, Xoconostle-Cazares B, Martínez-Antonio A, Brieba de Castro LG.   +17 more
europepmc   +1 more source

Single-Stranded DNA Binding Proteins and Their Identification Using Machine Learning-Based Approaches. [PDF]

Biomolecules, 2022
Guo JT, Malik F.
europepmc   +1 more source

DNA Binding Proteins for Control of Cell Growth [PDF]

, 1971

openalex   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Single-molecule fluorescence reveals the DNA unwinding mechanism of mitochondrial helicase TWINKLE and its interplay with single-stranded DNA-binding proteins. [PDF]

Nucleic Acids Res
Wang HY, Lee YY, Chien PJ, Tsai WA, Sun PJ, Wang LT, Wu CC, Fan HF.   +7 more
europepmc   +1 more source

Effects of Global and Specific DNA-Binding Proteins on Transcriptional Regulation of the E. coli bgl Operon. [PDF]

Int J Mol Sci, 2022
Tran D, Zhang Z, Lam KJK, Saier MH.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

DRBP-EDP: classification of DNA-binding proteins and RNA-binding proteins using ESM-2 and dual-path neural network. [PDF]

NAR Genom Bioinform
Mu Q, Yu G, Zhou G, He Y, Zhang J.
europepmc   +1 more source