Results 181 to 190 of about 26,138 (240)

Coupling of transcription and replication machineries in λ DNA replication initiation: evidence for direct interaction of Escherichia coli RNA polymerase and the λO protein [PDF]

, 2010
Anna Szambowska, Marcin Pierechod, Grzegorz Węgrzyn, Monika Glinkowska   +3 more
openalex   +1 more source

Mitigating Cellular Dysfunction Through Contaminant Reduction in Synthetic circRNA for High‐Efficiency mRNA‐Based Cell Reprogramming

Advanced Science, EarlyView.
This study addresses the challenges of synthetic circular RNAimpurities that trigger immune responses and hinder efficacy. Key immunogenic byproducts are identified and develop a multi‐step purification process that produces ultra‐pure circRNA and enhances yields by over 10‐fold.
Ziwei Zhang, Weiyu Li, Xiangyu Ren, Dengwang Luo, Xiushuang Yuan, Li Yu, Daming Wang, Yuhong Cao   +7 more
wiley   +1 more source

Zα and Zβ Localize ADAR1 to Flipons That Modulate Innate Immunity, Alternative Splicing, and Nonsynonymous RNA Editing. [PDF]

Int J Mol Sci
Herbert A, Cherednichenko O, Lybrand TP, Egli M, Poptsova M.   +4 more
europepmc   +1 more source

DNA-directed termination of mammalian RNA polymerase II

Lee Davidson, Jérôme O. Rouvière, Rui Sousa‐Luís, Takayuki Nojima, Nicholas Proudfoot, Torben Heick Jensen, Steven West   +6 more
openalex   +1 more source

Neophytadiene, a Plant Specialized Metabolite, Mediates the Virus‐Vector‐Plant Tripartite Interactions

Advanced Science, EarlyView.
Tomato chlorosis virus (ToCV) infection induces production of neophytadiene, a volatile resulting from chlorophyll degradation that is highly attractive to whiteflies. OBP2, an odorant‐binding protein from insect vector B. tabaci, exhibits a strong binding affinity for neophytadiene.
Xiao‐bin Shi, Hao Yue, Yan Wei, Evan L. Preisser, Pei Wang, Jiao Du, Ji‐xing Xia, Kai‐long Li, Xin Yang, Jian‐bin Chen, Song‐bai Zhang, Zhan‐hong Zhang, Xu‐guo Zhou, De‐yong Zhang, Yong Liu   +14 more
wiley   +1 more source

Faculty Opinions recommendation of Directed evolution of novel polymerase activities: mutation of a DNA polymerase into an efficient RNA polymerase.

, 2002
Makoto Komiyama
openalex   +3 more sources

Precise and Accurate DNA-3'/5-Ends Polishing with Thermus thermophilus Phage vb_Tt72 DNA Polymerase. [PDF]

Int J Mol Sci
Dorawa S, Kaczorowski T.
europepmc   +1 more source

An Intracellular Peptide Library Screening Platform Identifies Irreversible Covalent Transcription Factor Inhibitors

Advanced Science, EarlyView.
A peptide library screening platform has been developed to discover covalent transcription factor inhibitors. It identifies an antagonist cysteine residue, which forms an inhibitory disulphide with cJun C269. Conversion of this cysteine to an electrophile generates an irreversible and selective cJun inhibitor, validating this approach for covalent ...
Andrew Brennan, Scott Lovell, Keith W Vance, Jody M Mason   +3 more
wiley   +1 more source

A general and biomedical perspective of viral quasispecies. [PDF]

RNA
Domingo E, Martínez-González B, Somovilla P, García-Crespo C, Soria ME, de Ávila AI, Gadea I, Perales C.   +7 more
europepmc   +1 more source

Particles with RNA of High Molecular Weight and RNA-Directed DNA Polymerase in Human Brain Tumors

, 1973
W. Cuatico, J.-R. Cho, S. Spiegelman
openalex   +1 more source