Results 181 to 190 of about 98,603 (254)
Template nicking suppresses promoter-independent antisense transcription in IVT via R-loop-mediated strand displacement. [PDF]
Lee G, Ryu J, Jang J, Noh W, Kim DE.
europepmc +1 more source
Notch2 Directs aTreg Cell Fate toward Immunoregulation or Inflammatory Pyroptosis
Schematic illustration showing that the Notch2 intracellular domain (NICD2) facilitates pyroptosis resistance in activated Tregs through the RREB1/Foxo1 signaling pathway. In addition, Notch2‐mediated pyroptosis resistance in activated Tregs promotes immunoregulatory capacity, thereby attenuating Th2‐driven inflammatory responses in allergic rhinitis ...
Yue‐Long Qiao +10 more
wiley +1 more source
Real-time imaging of rotation during synthesis by the replisome. [PDF]
Retzer TM +4 more
europepmc +1 more source
Elemene increases SPP expression by competitively binding with miR‐130a‐5p to suppress SPP mRNA degradation. This led to more antigen/MHC‐I complexes being expressed on the cell surface, which consequently facilitated the recognition and killing of HCC cells by CTLs and enhancing the antitumor immune efficacy of anti‐PD‐1.
Menglan Wang +18 more
wiley +1 more source
Single-subunit RNA polymerases, KpnP, Ro45Iw, and CD23823, with precise terminal synthesis. [PDF]
Takatsuki H +4 more
europepmc +1 more source
Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits
Xu et al. discovers that switching off auxin transporters in soybean, PIN3a and PIN3b, disrupts auxin flow; this triggers ARF‐STF3/4 signal cascade to activate the nitrate importer NPF2.13 and soil nitrogen acquisition. Multi‐year field trials show edited soybeans maintain yield with higher oil content, offering a potential genetic route to improve ...
Huifang Xu +16 more
wiley +1 more source

