Results 121 to 130 of about 4,247,719 (263)

A Synergistic Consortium Involved in rac-Dichlorprop Degradation as Revealed by DNA Stable Isotope Probing and Metagenomic Analysis. [PDF]

Appl Environ Microbiol, 2021
Hu S, Liu G, Zhang L, Gan Y, Wang B, Freilich S, Jiang J.   +6 more
europepmc   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Physiological versatility of ANME-1 and Bathyarchaeotoa-8 archaea evidenced by inverse stable isotope labeling

Microbiome
Background The trophic strategy is one key principle to categorize microbial lifestyles, by broadly classifying microorganisms based on the combination of their preferred carbon sources, electron sources, and electron sinks.
Xiuran Yin, Guowei Zhou, Mingwei Cai, Tim Richter-Heitmann, Qing-Zeng Zhu, Mara Maeke, Ajinkya C. Kulkarni, Rolf Nimzyk, Marcus Elvert, Michael W. Friedrich   +9 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Versatile nitrate-respiring heterotrophs are previously concealed contributors to sulfur cycle

Nature Communications
Heterotrophic denitrifiers play crucial roles in global carbon and nitrogen cycling. However, their inability to oxidize sulfide renders them vulnerable to this toxic molecule, which inhibits the key enzymatic reaction responsible for reducing nitrous ...
Bo Shao, Yuan-Guo Xie, Long Zhang, Yang Ruan, Bin Liang, Ruochen Zhang, Xijun Xu, Wei Wang, Zhengda Lin, Xuanyuan Pei, Xueting Wang, Lei Zhao, Xu Zhou, Xiaohui Wu, Defeng Xing, Aijie Wang, Duu-Jong Lee, Nanqi Ren, Donald E. Canfield, Brian P. Hedlund, Zheng-Shuang Hua, Chuan Chen   +21 more
doaj   +1 more source

Recent Advances in Top‐Down Proteomics for Single‐Cell Research

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Individual cells have distinctive molecular characteristics, including biologically relevant proteoforms. Although single‐cell (SC) molecular omics offer unprecedented insights into cellular heterogeneity and function, the characterization of proteoforms in SCs remains an uncharted territory.
Jake A. Melby, Pei Su, Fabio P. Gomes
wiley   +1 more source

Mass Spectrometry‐Based Extracellular Vesicle Proteomics for Biomarker Discovery

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicle (EV) proteomics has emerged as a powerful platform for decoding intercellular communication and advancing biomarker discovery across human diseases. EVs carry proteins that reflect their cells of origin, offering a minimally invasive window into physiological and pathological processes.
Ya‐Juan Liu, Juan Peng, Chao Kang
wiley   +1 more source

Keeping It Native: Non‐Denaturing Approaches to Top‐Down Protein Mass Spectrometry

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Top‐down proteomics and top‐down mass spectrometry approaches provide direct characterization of proteoforms; the specific molecular forms of proteins, including post‐translational modifications, truncations, alternative splicing, and sequence variants.
Michael Xiao, Edvaldo Vasconcelos Soares Maciel, Frederik Lermyte, Owen S. Skinner   +3 more
wiley   +1 more source

Body Size, Dental Pathology, and Maternal Genetic Diversity of Ancient Horses in the Eastern Baltic Sea Region and Western Russia

International Journal of Osteoarchaeology, EarlyView.
ABSTRACT The early evolutionary history of modern domestic horses (Equus caballus/Equus ferus caballus), known as the DOM2 lineage, is well documented due to numerous archaeological and ancient DNA (aDNA) studies. Although many uncertainties remain in the domestication timeline, current evidence suggests that the domestication of modern horses began in
Johanna Honka, Daniela Salazar, Arthur O. Askeyev, Igor V. Askeyev, Oleg V. Askeyev, Jouni Aspi, Gulshat Sh. Asylgaraeva, Markku Niskanen, Kristiina Mannermaa, Suvi Olli, Noora Piipponen, Giedrė Piličiauskienė, Dilyara N. Shaymuratova, Renat R. Valiev, Laura Kvist   +14 more
wiley   +1 more source

Validation of Heavy-Water Stable Isotope Probing for the Characterization of Rapidly Responding Soil Bacteria†

, 2010
Rapid responses of bacteria to sudden changes in their environment can have important implications for the structure and function of microbial communities.
Zachary T. A, Zachary T. Aanderud, Jay T. Lennon   +2 more
core   +1 more source