Results 11 to 20 of about 6,079,340 (257)

Identification of QTLs for root color and carotenoid contents in Japanese orange carrot F2 populations

Scientific Reports, 2022
Carrot is a major source of provitamin A in a human diet. Two of the most important traits for carrot breeding are carotenoid contents and root color.
Taeko Shibaya, Chika Kuroda, Hisano Tsuruoka, Chiharu Minami, Akiko Obara, Shinobu Nakayama, Yoshie Kishida, Takayoshi Fujii, Sachiko Isobe   +8 more
doaj   +1 more source

Vortex fluidics-mediated DNA rescue from formalin-fixed museum specimens. [PDF]

, 2020
DNA from formalin-preserved tissue could unlock a vast repository of genetic information stored in museums worldwide. However, formaldehyde crosslinks proteins and DNA, and prevents ready amplification and DNA sequencing.
Girguis, Peter R, Majumdar, Sudipta, Phillips, Jessica M, Raston, Colin L, Reese, Aspen T, Totoiu, Christian A, Weiss, Gregory A   +6 more
core   +1 more source

Transcriptome analysis of Clavibacter michiganensis subsp. michiganensis-infected tomatoes: a role of salicylic acid in the host response

BMC Plant Biology, 2021
Bacterial canker of tomato (Solanum lycopersicon) caused by the Gram-positive bacterium Clavibacter michiganensis subsp. michiganensis (Cmm) is an economically important disease.
Naoki Yokotani, Yoshinori Hasegawa, Masaru Sato, Hideki Hirakawa, Yusuke Kouzai, Yoko Nishizawa, Eiji Yamamoto, Yoshiki Naito, Sachiko Isobe   +8 more
doaj   +1 more source

DNA methylation and DNA methyltransferases [PDF]

, 2017
The prevailing views as to the form, function, and regulation of genomic methylation patterns have their origin many years in the past, at a time when the structure of the mammalian genome was only dimly perceived, when the number of protein-encoding ...
Bestor, Timothy H, Boulard, Mathieu, Edwards, John R, Yarychkivska, Olya   +3 more
core   +3 more sources

Ceramic materials lead to underestimated DNA quantifications : a method for reliable measurements [PDF]

, 2010
In the context of investigating cell-material interactions or of material-guided generation of tissues, DNA quantification represents an elective method to precisely assess the number of cells attached or embedded within different substrates. Nonetheless,
Martin, I., Piccinini, E., Sadr, N.
core   +1 more source

Using eggshell membranes as a DNA source for population genetic research [PDF]

, 2009
In the context of population genetic research, a faster and less invasive method of DNA sampling would allow large-scale assessments of genetic diversity and genetic differentiation with the help of volunteer observers.
Broekman, J., Kentie, R., Musters, C.J.M., Snoo, G.R., de, Trimbos, K.B.   +4 more
core   +3 more sources

CRISPAltRations: A validated cloud-based approach for interrogation of double-strand break repair mediated by CRISPR genome editing

Molecular Therapy: Methods & Clinical Development, 2021
CRISPR systems enable targeted genome editing in a wide variety of organisms by introducing single- or double-strand DNA breaks, which are repaired using endogenous molecular pathways.
Gavin Kurgan, Rolf Turk, Heng Li, Nathan Roberts, Garrett R. Rettig, Ashley M. Jacobi, Lauren Tso, Morgan Sturgeon, Massimo Mertens, Roel Noten, Kurt Florus, Mark A. Behlke, Yu Wang, Matthew S. McNeill   +13 more
doaj   +1 more source

Methylation of the imprinted GNAS1 gene in cell-free plasma DNA : equal steady-state quantities of methylated and unmethylated DNA in plasma [PDF]

, 2008
Background Genomic DNA sequences in cell-free plasma are biomarkers of cancer prognosis, where characteristic changes in methylation of tumour suppressor or oncogene DNA regions are indicative of changes in gene activity.
Alberry, Anker, Bauer, Bianchi, Birch, Chim, Deligezer, Eggermann, Francesco Crea, Grunau, Honda, Jahr, Januchowski, Kamaljit Chatha, Kawakami, Li, Lo, Lui, Robert W. Old, Selina Elsenheimer, Sorenson, Stroun, Stroun, Tsang, Van der Schoot, Vasioukhin, William M. Puszyk   +26 more
core   +1 more source

Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands

Nature Communications, 2020
The RNase activity of Inositol-Requiring Enzyme 1 (IRE1) can be allosterically regulated by ATP-competitive inhibitors of the IRE1 kinase domain. Here, the authors identify ATP-competitive IRE1 RNase activators with improved selectivity and cellular ...
Elena Ferri, Adrien Le Thomas, Heidi Ackerly Wallweber, Eric S. Day, Benjamin T. Walters, Susan E. Kaufman, Marie-Gabrielle Braun, Kevin R. Clark, Maureen H. Beresini, Kyle Mortara, Yung-Chia A. Chen, Breanna Canter, Wilson Phung, Peter S. Liu, Alfred Lammens, Avi Ashkenazi, Joachim Rudolph, Weiru Wang   +17 more
doaj   +1 more source

Biological Consequences of Tightly Bent DNA: The Other Life of a Macromolecular Celebrity [PDF]

, 2006
The mechanical properties of DNA play a critical role in many biological functions. For example, DNA packing in viruses involves confining the viral genome in a volume (the viral capsid) with dimensions that are comparable to the DNA persistence length ...
Garcia, Hernan G., Grayson, Paul, Han, Lin, Inamdar, Mandar, Kondev, Jane, Nelson, Philip C., Phillips, Rob, Widom, Jonathan, Wiggins, Paul A.   +8 more
core   +3 more sources