Results 31 to 40 of about 4,554,738 (310)
Managing DNA polymerases: Coordinating DNA replication, DNA repair, and DNA recombination [PDF]
Proceedings of the National Academy of Sciences, 2001 Two important and timely questions with respect to DNA replication, DNA recombination, and DNA repair are: ( i ) what controls which DNA polymerase gains access to a particular primer-terminus, and ( ii ) what determines whether a DNA polymerase hands ...
M D, Sutton, G C, Walker
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Electronic transport in DNA [PDF]
, 2005 We study the electronic properties of DNA by way of a tight-binding model applied to four particular DNA sequences. The charge transfer properties are presented in terms of localization lengths (crudely speaking, the length over which electrons travel).
Klotsa, Daphne +3 more
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FlavonoidSearch: A system for comprehensive flavonoid annotation by mass spectrometry
Scientific Reports, 2017 Currently, in mass spectrometry-based metabolomics, limited reference mass spectra are available for flavonoid identification. In the present study, a database of probable mass fragments for 6,867 known flavonoids (FsDatabase) was manually constructed ...
Nayumi Akimoto +10 more
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Scientific Reports, 2021 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Zhonghui Thong +5 more
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Linguistic profile in individuals with 22q11.2 syndrome: A systematic review
Language and Health22q11.2 syndrome is the second most common genetic condition worldwide, where communication, language, and speech are significantly affected to varying degrees.
Esther Moraleda Sepúlveda +2 more
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Molecular mechanisms and kinetics between DNA and DNA binding ligands [PDF]
, 2005 Sischka A, Tönsing K, Eckel R, et al. Molecular mechanisms and kinetics between DNA and DNA binding ligands. Biophysical Journal. 2005;88(1):404-411.Mechanical properties of single double-stranded DNA (dsDNA) in the presence of different binding ligands ...
Anselmetti, Dario +9 more
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Cellular Processing Pathways Contribute to the Activation of Etoposide- Induced DNA Damage Responses
, 2009 Cytotoxic action (tumor cell killing) and carcinogenic side effect ( therapy-related secondary leukemia) of etoposide are closely related to its ability in stabilizing topoisomerase II cleavable complex (TOP2cc), a unique form of protein- linked DNA ...
FAN, JIA-RONG;PENG, AN-LIN;LO, SHU-CHI;HUANG, TING-HSIANG;LI, TSAI-KUN +1 more
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The RecQ DNA Helicases in DNA Repair [PDF]
Annual Review of Genetics, 2010 The RecQ helicases are conserved from bacteria to humans and play a critical role in genome stability. In humans, loss of RecQ gene function is associated with cancer predisposition and/or premature aging. Recent experiments have shown that the RecQ helicases function during distinct steps during DNA repair; DNA end resection, displacement-loop (D-loop)
Bernstein, Kara +2 more
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High cell-surface density of HER2 deforms cell membranes
Nature Communications, 2016 HER2 is frequently overexpressed in breast cancer in association with increased metastatic potential. Here, the authors show that HER2 overexpression causes deformation of cell membranes in a signalling-independent manner that contributes to the disease ...
Inhee Chung +8 more
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DNA glycosylases: in DNA repair and beyond [PDF]
Chromosoma, 2011 The base excision repair machinery protects DNA in cells from the damaging effects of oxidation, alkylation, and deamination; it is specialized to fix single-base damage in the form of small chemical modifications. Base modifications can be mutagenic and/or cytotoxic, depending on how they interfere with the template function of the DNA during ...
Jacobs, A. L., Schar, P.
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