Results 201 to 210 of about 8,837,195 (335)

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Rapamycin Exerts Its Geroprotective Effects in the Ageing Human Immune System by Enhancing Resilience Against DNA Damage. [PDF]

Aging Cell
Kell L, Jones EJ, Gharahdaghi N, Wilkinson DJ, Smith K, Atherton PJ, Simon AK, Cox LS, Alsaleh G.   +8 more
europepmc   +1 more source

Biological identifications through DNA barcodes

Proceedings of the Royal Society of London. Series B: Biological Sciences, 2003
P. Hebert, A. Cywinska, S. Ball, Jeremy R. deWaard   +3 more
semanticscholar   +1 more source

The Role of Loop Stacking in the Dynamics of DNA Hairpin Formation [PDF]

, 2014
Majid Mosayebi, Flavio Romano, Thomas E. Ouldridge, Ard A. Louis, Jonathan P. K. Doye   +4 more
openalex   +1 more source

Pregenomic RNA Launch Hepatitis B Virus Replication System Facilitates the Mechanistic Study of Antiviral Agents and Drug-Resistant Variants on Covalently Closed Circular DNA Synthesis

, 2022
Qiong Zhao, Jinhong Chang, René Rijnbrand, Angela M. Lam, Michael J. Sofia, Andrea Cuconati, Ju‐Tao Guo   +6 more
openalex   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Obesity and cancer: Relevance of DNA damage response. [PDF]

Transl Oncol
Deshmukh B, Ajay AK, Bhat MK.
europepmc   +1 more source

DNA/DNA hybridization to microarrays reveals gene-specific differences between closely related microbial genomes

, 2001
Alison E. Murray, Douglas P. Lies, G. Li, Kenneth H. Nealson, Jizhong Zhou, James M. Tiedje   +5 more
openalex   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Properties and Limitations of eDNA Substrates for Terrestrial Animal Monitoring. [PDF]

Mol Ecol Resour
Zhao B, Andermann T.
europepmc   +1 more source